SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		5 / 12 GLY A  31
ASP A  39
LEU A 126
VAL A 127
LEU A 141
 None
 1.19A 1r30A-5xjvA:
undetectable		 1r30A-5xjvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		5 / 10 LEU A 178
PHE A 107
THR A 138
ALA A 111
ALA A 110
 None
 1.24A 1wygA-5xjvA:
undetectable		 1wygA-5xjvA:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		4 / 4 MET A 145
PRO A 167
ASP A 179
ARG A 160
 None
 1.13A 2qm9B-5xjvA:
undetectable		 2qm9B-5xjvA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		3 / 3 ARG A  37
ASP A  39
ASP A  49
 None
 0.89A 3jayA-5xjvA:
undetectable		 3jayA-5xjvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		5 / 9 VAL A  93
HIS A  72
LEU A 141
ARG A 135
ALA A 137
 None
None
None
PO4  A 201 (-3.9A)
None
 1.30A 6c2mB-5xjvA:
undetectable		 6c2mB-5xjvA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5xjv DUAL SPECIFICITY
PROTEIN PHOSPHATASE
13 ISOFORM A
(Homo
sapiens) 		5 / 12 VAL A  88
SER A  87
THR A  65
ALA A 123
PHE A 113
 None
 1.41A 6drxA-5xjvA:
undetectable		 6drxA-5xjvA:
undetectable