SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xk8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_J_CHDJ3060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.97A	1v54A-5xk8A: undetectable 1v54J-5xk8A: undetectable	1v54A-5xk8A: undetectable 1v54J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1V54_W_CHDW4060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE I CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 7	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.00A	1v54N-5xk8A: undetectable 1v54W-5xk8A: undetectable	1v54N-5xk8A: undetectable 1v54W-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYR_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.98A	2dyrA-5xk8A: undetectable 2dyrJ-5xk8A: undetectable	2dyrA-5xk8A: undetectable 2dyrJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_J_CHDJ101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	2dysA-5xk8A: undetectable 2dysJ-5xk8A: undetectable	2dysA-5xk8A: undetectable 2dysJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DYS_W_CHDW101_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.97A	2dysN-5xk8A: undetectable 2dysW-5xk8A: undetectable	2dysN-5xk8A: undetectable 2dysW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIJ_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.03A	2eijA-5xk8A: undetectable 2eijJ-5xk8A: undetectable	2eijA-5xk8A: undetectable 2eijJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIK_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 7	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.01A	2eikA-5xk8A: undetectable 2eikJ-5xk8A: undetectable	2eikA-5xk8A: undetectable 2eikJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIL_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	2eilA-5xk8A: undetectable 2eilJ-5xk8A: undetectable	2eilA-5xk8A: undetectable 2eilJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	2eimJ-5xk8A: undetectable	2eimJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	2eimW-5xk8A: undetectable	2eimW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIN_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.97A	2einN-5xk8A: undetectable 2einW-5xk8A: undetectable	2einN-5xk8A: undetectable 2einW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZXW_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.01A	2zxwA-5xk8A: undetectable 2zxwJ-5xk8A: undetectable	2zxwA-5xk8A: undetectable 2zxwJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.00A	3abmA-5xk8A: undetectable 3abmJ-5xk8A: undetectable	3abmA-5xk8A: undetectable 3abmJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.93A	3ag1J-5xk8A: undetectable	3ag1J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_W_CHDW1059_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.90A	3ag1N-5xk8A: undetectable 3ag1W-5xk8A: undetectable	3ag1N-5xk8A: undetectable 3ag1W-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.04A	3ag2J-5xk8A: undetectable	3ag2J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.04A	3ag4J-5xk8A: undetectable	3ag4J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_A_CHDA2_0 (FERROCHELATASE)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	MET A 69 ARG A 106 GLY A 89 MET A 123	GPP A 501 ( 3.7A) None None None	1.43A	3aqiA-5xk8A: 2.9	3aqiA-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASN_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.04A	3asnA-5xk8A: undetectable 3asnJ-5xk8A: undetectable	3asnA-5xk8A: undetectable 3asnJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ASO_J_CHDJ60_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.02A	3asoA-5xk8A: undetectable 3asoJ-5xk8A: undetectable	3asoA-5xk8A: undetectable 3asoJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SPK_A_TPVA100_1 (HIV-1 PROTEASE)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	5 / 11	ARG A 13 LEU A 189 ASN A 191 ASP A 31 ILE A 20	None	1.14A	3spkA-5xk8A: undetectable	3spkA-5xk8A: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WG7_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.05A	3wg7N-5xk8A: undetectable 3wg7W-5xk8A: undetectable	3wg7N-5xk8A: undetectable 3wg7W-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_B_ACTB701_0 (RNA (33-MER) RNA POLYMERASE 3D-POL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	3 / 3	HIS A 118 GLY A 89 ILE A 120	None	0.62A	4k50A-5xk8A: undetectable	4k50A-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K50_J_ACTJ701_0 (RNA (33-MER) RNA POLYMERASE 3D-POL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	3 / 3	HIS A 118 GLY A 89 ILE A 120	None	0.60A	4k50I-5xk8A: undetectable	4k50I-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WQ4_B_ACTB403_0 (TRNA N6-ADENOSINE THREONYLCARBAMOYLTRA NSFERASE)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	3 / 3	ARG A 210 ASP A 209 ARG A 211	None	0.68A	4wq4B-5xk8A: undetectable	4wq4B-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CXV_A_0HKA501_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARI NIC ACETYLCHOLINE RECEPTOR M1)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	3 / 3	THR A 2 THR A 46 PHE A 48	None	0.85A	5cxvA-5xk8A: undetectable	5cxvA-5xk8A: 9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.90A	5w97J-5xk8A: undetectable	5w97J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.00A	5wauJ-5xk8A: undetectable	5wauJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.96A	5x19J-5xk8A: undetectable	5x19J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	5x1bJ-5xk8A: undetectable	5x1bJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.96A	5x1bW-5xk8A: undetectable	5x1bW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.00A	5x1fA-5xk8A: undetectable 5x1fJ-5xk8A: undetectable	5x1fA-5xk8A: undetectable 5x1fJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1F_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.99A	5x1fW-5xk8A: undetectable	5x1fW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.04A	5z86J-5xk8A: undetectable	5z86J-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z86_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.02A	5z86N-5xk8A: undetectable 5z86W-5xk8A: undetectable	5z86N-5xk8A: undetectable 5z86W-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZCO_W_CHDW101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 6	TYR A 26 MET A 29 THR A 30 LEU A 33	None	1.01A	5zcoN-5xk8A: undetectable 5zcoW-5xk8A: undetectable	5zcoN-5xk8A: undetectable 5zcoW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.92A	6nknJ-5xk8A: undetectable	6nknJ-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_W_CHDW102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 5	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.96A	6nknW-5xk8A: undetectable	6nknW-5xk8A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMF_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5xk8	UNDECAPRENYL DIPHOSPHATE SYNTHASE (Streptomyces sp. CNH189)	4 / 7	TYR A 26 MET A 29 THR A 30 LEU A 33	None	0.90A	6nmfA-5xk8A: undetectable 6nmfJ-5xk8A: undetectable	6nmfA-5xk8A: undetectable 6nmfJ-5xk8A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1V54_J_CHDJ3060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.97A","1v54A-5xk8A:undetectable;1v54J-5xk8A:undetectable","1v54A-5xk8A:undetectable;1v54J-5xk8A:undetectable"],["1V54_W_CHDW4060_0","CYTOCHROME C OXIDASE POLYPEPTIDE I;CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.00A","1v54N-5xk8A:undetectable;1v54W-5xk8A:undetectable","1v54N-5xk8A:undetectable;1v54W-5xk8A:undetectable"],["2DYR_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.98A","2dyrA-5xk8A:undetectable;2dyrJ-5xk8A:undetectable","2dyrA-5xk8A:undetectable;2dyrJ-5xk8A:undetectable"],["2DYS_J_CHDJ101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","2dysA-5xk8A:undetectable;2dysJ-5xk8A:undetectable","2dysA-5xk8A:undetectable;2dysJ-5xk8A:undetectable"],["2DYS_W_CHDW101_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.97A","2dysN-5xk8A:undetectable;2dysW-5xk8A:undetectable","2dysN-5xk8A:undetectable;2dysW-5xk8A:undetectable"],["2EIJ_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.03A","2eijA-5xk8A:undetectable;2eijJ-5xk8A:undetectable","2eijA-5xk8A:undetectable;2eijJ-5xk8A:undetectable"],["2EIK_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.01A","2eikA-5xk8A:undetectable;2eikJ-5xk8A:undetectable","2eikA-5xk8A:undetectable;2eikJ-5xk8A:undetectable"],["2EIL_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","2eilA-5xk8A:undetectable;2eilJ-5xk8A:undetectable","2eilA-5xk8A:undetectable;2eilJ-5xk8A:undetectable"],["2EIM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","2eimJ-5xk8A:undetectable","2eimJ-5xk8A:undetectable"],["2EIM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","2eimW-5xk8A:undetectable","2eimW-5xk8A:undetectable"],["2EIN_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.97A","2einN-5xk8A:undetectable;2einW-5xk8A:undetectable","2einN-5xk8A:undetectable;2einW-5xk8A:undetectable"],["2ZXW_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.01A","2zxwA-5xk8A:undetectable;2zxwJ-5xk8A:undetectable","2zxwA-5xk8A:undetectable;2zxwJ-5xk8A:undetectable"],["3ABM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.00A","3abmA-5xk8A:undetectable;3abmJ-5xk8A:undetectable","3abmA-5xk8A:undetectable;3abmJ-5xk8A:undetectable"],["3AG1_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.93A","3ag1J-5xk8A:undetectable","3ag1J-5xk8A:undetectable"],["3AG1_W_CHDW1059_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.90A","3ag1N-5xk8A:undetectable;3ag1W-5xk8A:undetectable","3ag1N-5xk8A:undetectable;3ag1W-5xk8A:undetectable"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.04A","3ag2J-5xk8A:undetectable","3ag2J-5xk8A:undetectable"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.04A","3ag4J-5xk8A:undetectable","3ag4J-5xk8A:undetectable"],["3AQI_A_CHDA2_0","FERROCHELATASE","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"MET A  69;ARG A 106;GLY A  89;MET A 123","GPP A 501 ( 3.7A);None;None;None","1.43A","3aqiA-5xk8A:2.9","3aqiA-5xk8A:undetectable"],["3ASN_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.04A","3asnA-5xk8A:undetectable;3asnJ-5xk8A:undetectable","3asnA-5xk8A:undetectable;3asnJ-5xk8A:undetectable"],["3ASO_J_CHDJ60_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.02A","3asoA-5xk8A:undetectable;3asoJ-5xk8A:undetectable","3asoA-5xk8A:undetectable;3asoJ-5xk8A:undetectable"],["3SPK_A_TPVA100_1","HIV-1 PROTEASE","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",5,"ARG A  13;LEU A 189;ASN A 191;ASP A  31;ILE A  20","None","1.14A","3spkA-5xk8A:undetectable","3spkA-5xk8A:15.15"],["3WG7_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.05A","3wg7N-5xk8A:undetectable;3wg7W-5xk8A:undetectable","3wg7N-5xk8A:undetectable;3wg7W-5xk8A:undetectable"],["4K50_B_ACTB701_0","RNA (33-MER);RNA POLYMERASE 3D-POL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",3,"HIS A 118;GLY A  89;ILE A 120","None","0.62A","4k50A-5xk8A:undetectable","4k50A-5xk8A:undetectable"],["4K50_J_ACTJ701_0","RNA (33-MER);RNA POLYMERASE 3D-POL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",3,"HIS A 118;GLY A  89;ILE A 120","None","0.60A","4k50I-5xk8A:undetectable","4k50I-5xk8A:undetectable"],["4WQ4_B_ACTB403_0","TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",3,"ARG A 210;ASP A 209;ARG A 211","None","0.68A","4wq4B-5xk8A:undetectable","4wq4B-5xk8A:undetectable"],["5CXV_A_0HKA501_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M1,ENDOLYSIN,MUSCARINIC ACETYLCHOLINE RECEPTOR M1","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",3,"THR A   2;THR A  46;PHE A  48","None","0.85A","5cxvA-5xk8A:undetectable","5cxvA-5xk8A:9.38"],["5W97_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.90A","5w97J-5xk8A:undetectable","5w97J-5xk8A:undetectable"],["5WAU_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.00A","5wauJ-5xk8A:undetectable","5wauJ-5xk8A:undetectable"],["5X19_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.96A","5x19J-5xk8A:undetectable","5x19J-5xk8A:undetectable"],["5X1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","5x1bJ-5xk8A:undetectable","5x1bJ-5xk8A:undetectable"],["5X1B_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.96A","5x1bW-5xk8A:undetectable","5x1bW-5xk8A:undetectable"],["5X1F_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.00A","5x1fA-5xk8A:undetectable;5x1fJ-5xk8A:undetectable","5x1fA-5xk8A:undetectable;5x1fJ-5xk8A:undetectable"],["5X1F_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.99A","5x1fW-5xk8A:undetectable","5x1fW-5xk8A:undetectable"],["5Z86_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.04A","5z86J-5xk8A:undetectable","5z86J-5xk8A:undetectable"],["5Z86_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.02A","5z86N-5xk8A:undetectable;5z86W-5xk8A:undetectable","5z86N-5xk8A:undetectable;5z86W-5xk8A:undetectable"],["5ZCO_W_CHDW101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","1.01A","5zcoN-5xk8A:undetectable;5zcoW-5xk8A:undetectable","5zcoN-5xk8A:undetectable;5zcoW-5xk8A:undetectable"],["6NKN_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.92A","6nknJ-5xk8A:undetectable","6nknJ-5xk8A:undetectable"],["6NKN_W_CHDW102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.96A","6nknW-5xk8A:undetectable","6nknW-5xk8A:undetectable"],["6NMF_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 1;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5xk8","UNDECAPRENYL DIPHOSPHATE SYNTHASE","Streptomyces sp. CNH189",4,"TYR A  26;MET A  29;THR A  30;LEU A  33","None","0.90A","6nmfA-5xk8A:undetectable;6nmfJ-5xk8A:undetectable","6nmfA-5xk8A:undetectable;6nmfJ-5xk8A:undetectable"]]