SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5xlk FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Serratia
marcescens) 		4 / 7 GLY A 135
ILE A 132
VAL A 166
GLN A 105
 None
 0.60A 3fi0E-5xlkA:
undetectable		 3fi0E-5xlkA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_G_TRPG1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5xlk FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Serratia
marcescens) 		4 / 8 GLY A 135
ILE A 132
VAL A 166
GLN A 105
 None
 0.73A 3fi0G-5xlkA:
undetectable		 3fi0G-5xlkA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5xlk FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Serratia
marcescens) 		3 / 3 GLN A 110
THR A 109
THR A 108
 None
 0.77A 4fu9A-5xlkA:
undetectable		 4fu9A-5xlkA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5xlk FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Serratia
marcescens) 		3 / 3 GLN A 110
THR A 109
THR A 108
 None
 0.77A 4fufA-5xlkA:
undetectable		 4fufA-5xlkA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5xlk FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 2
(Serratia
marcescens) 		4 / 8 ALA A 111
MET A 219
LEU A 120
LEU A 203
 None
 1.21A 5dzkF-5xlkA:
undetectable
5dzkT-5xlkA:
undetectable		 5dzkF-5xlkA:
24.59
5dzkT-5xlkA:
2.27