SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V41_F_BEZF1222_0 (PEROXIREDOXIN 6.)	5xna	SAHS1 (Ramazzottius varieornatus)	4 / 7	PRO A 88 VAL A 87 SER A 86 GLU A 42	None	1.05A	2v41E-5xnaA: undetectable 2v41F-5xnaA: undetectable	2v41E-5xnaA: 21.15 2v41F-5xnaA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_A_ACTA501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	5xna	SAHS1 (Ramazzottius varieornatus)	4 / 7	ASP A 139 VAL A 96 ILE A 85 TYR A 117	EDO A 208 (-3.2A) None None EDO A 207 (-4.6A)	1.09A	2yfbA-5xnaA: undetectable	2yfbA-5xnaA: 18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	5xna	SAHS1 (Ramazzottius varieornatus)	4 / 6	ASP A 139 VAL A 96 ILE A 85 TYR A 117	EDO A 208 (-3.2A) None None EDO A 207 (-4.6A)	1.10A	2yfbB-5xnaA: undetectable	2yfbB-5xnaA: 18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8I_A_RO7A1_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR ALPHA)	5xna	SAHS1 (Ramazzottius varieornatus)	5 / 12	TYR A 117 ILE A 54 ILE A 85 HIS A 83 VAL A 96	EDO A 207 (-4.6A) None None None None	1.46A	3g8iA-5xnaA: undetectable	3g8iA-5xnaA: 17.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2V41_F_BEZF1222_0","PEROXIREDOXIN 6.","5xna","SAHS1","Ramazzottius varieornatus",4,"PRO A  88;VAL A  87;SER A  86;GLU A  42","None","1.05A","2v41E-5xnaA:undetectable;2v41F-5xnaA:undetectable","2v41E-5xnaA:21.15;2v41F-5xnaA:21.15"],["2YFB_A_ACTA501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","5xna","SAHS1","Ramazzottius varieornatus",4,"ASP A 139;VAL A  96;ILE A  85;TYR A 117","EDO A 208 (-3.2A);None;None;EDO A 207 (-4.6A)","1.09A","2yfbA-5xnaA:undetectable","2yfbA-5xnaA:18.77"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","5xna","SAHS1","Ramazzottius varieornatus",4,"ASP A 139;VAL A  96;ILE A  85;TYR A 117","EDO A 208 (-3.2A);None;None;EDO A 207 (-4.6A)","1.10A","2yfbB-5xnaA:undetectable","2yfbB-5xnaA:18.77"],["3G8I_A_RO7A1_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR ALPHA","5xna","SAHS1","Ramazzottius varieornatus",5,"TYR A 117;ILE A  54;ILE A  85;HIS A  83;VAL A  96","EDO A 207 (-4.6A);None;None;None;None","1.46A","3g8iA-5xnaA:undetectable","3g8iA-5xnaA:17.56"]]