SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J5M_A_ACTA1321_0 (CHLOROPEROXIDASE)	5xnd	PARVALBUMIN BETA (Scomber japonicus)	4 / 6	LEU A 36 PHE A 67 ILE A 51 ALA A 47	None	1.06A	2j5mA-5xndA: undetectable	2j5mA-5xndA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OD9_A_NCAA3721_0 (NAD-DEPENDENT DEACETYLASE HST2)	5xnd	PARVALBUMIN BETA (Scomber japonicus)	3 / 3	PHE A 25 PHE A 30 PHE A 31	None	0.87A	2od9A-5xndA: undetectable	2od9A-5xndA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QQG_A_NCAA3721_0 (NAD-DEPENDENT DEACETYLASE HST2)	5xnd	PARVALBUMIN BETA (Scomber japonicus)	3 / 3	PHE A 25 PHE A 30 PHE A 31	None	0.87A	2qqgA-5xndA: undetectable	2qqgA-5xndA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U9F_L_CLML221_0 (CHLORAMPHENICOL ACETYLTRANSFERASE)	5xnd	PARVALBUMIN BETA (Scomber japonicus)	5 / 12	PHE A 31 CYH A 34 PHE A 103 LEU A 7 VAL A 12	None	1.46A	3u9fJ-5xndA: undetectable 3u9fL-5xndA: undetectable	3u9fJ-5xndA: undetectable 3u9fL-5xndA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2J5M_A_ACTA1321_0","CHLOROPEROXIDASE","5xnd","PARVALBUMIN BETA","Scomber japonicus",4,"LEU A  36;PHE A  67;ILE A  51;ALA A  47","None","1.06A","2j5mA-5xndA:undetectable","2j5mA-5xndA:undetectable"],["2OD9_A_NCAA3721_0","NAD-DEPENDENT DEACETYLASE HST2","5xnd","PARVALBUMIN BETA","Scomber japonicus",3,"PHE A  25;PHE A  30;PHE A  31","None","0.87A","2od9A-5xndA:undetectable","2od9A-5xndA:undetectable"],["2QQG_A_NCAA3721_0","NAD-DEPENDENT DEACETYLASE HST2","5xnd","PARVALBUMIN BETA","Scomber japonicus",3,"PHE A  25;PHE A  30;PHE A  31","None","0.87A","2qqgA-5xndA:undetectable","2qqgA-5xndA:undetectable"],["3U9F_L_CLML221_0","CHLORAMPHENICOL ACETYLTRANSFERASE","5xnd","PARVALBUMIN BETA","Scomber japonicus",5,"PHE A  31;CYH A  34;PHE A 103;LEU A   7;VAL A  12","None","1.46A","3u9fJ-5xndA:undetectable;3u9fL-5xndA:undetectable","3u9fJ-5xndA:undetectable;3u9fL-5xndA:undetectable"]]