SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xne'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 5xne -
(-) 		5 / 11 HIS B 191
HIS B 204
VAL B 144
LEU B  59
LEU B  31
 ZN  B 301 (-3.5A)
ZN  B 301 (-3.3A)
None
None
None
 1.40A 1dmyA-5xneB:
undetectable		 1dmyA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 5xne -
(-) 		3 / 3 ASP B  33
ASP B 239
ASP B 232
 None
 0.70A 1eizA-5xneB:
undetectable		 1eizA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 5xne -
(-) 		3 / 3 ASP B  33
ASP B 239
ASP B 232
 None
 0.71A 1ej0A-5xneB:
undetectable		 1ej0A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.82A 1os2A-5xneB:
undetectable		 1os2A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.80A 1os2D-5xneB:
undetectable		 1os2D-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.14A 1os2D-5xneB:
undetectable		 1os2D-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.80A 1uttA-5xneB:
undetectable		 1uttA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.16A 1uttA-5xneB:
undetectable		 1uttA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.82A 1utzA-5xneB:
undetectable		 1utzA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.16A 1utzA-5xneB:
undetectable		 1utzA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.77A 1utzB-5xneB:
undetectable		 1utzB-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.17A 1utzB-5xneB:
undetectable		 1utzB-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 6 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.81A 1y93A-5xneB:
undetectable		 1y93A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 5xne -
(-) 		5 / 10 HIS B 204
HIS B 193
HIS B 191
THR B 250
GLU B 251
 ZN  B 301 (-3.3A)
ZN  B 301 (-3.4A)
ZN  B 301 (-3.5A)
None
ZN  B 301 ( 4.5A)
 1.26A 2dttD-5xneB:
undetectable
2dttF-5xneB:
undetectable		 2dttD-5xneB:
undetectable
2dttF-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EFJ_A_37TA502_1
(3,7-DIMETHYLXANTHINE
METHYLTRANSFERASE)		 5xne -
(-) 		5 / 12 LEU B 210
PHE B 136
ILE B  53
ILE B 130
TYR B 208
 None
 1.28A 2efjA-5xneB:
undetectable		 2efjA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.79A 2hu6A-5xneB:
undetectable		 2hu6A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.14A 2hu6A-5xneB:
undetectable		 2hu6A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 6 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.85A 2ow9A-5xneB:
undetectable		 2ow9A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 5xne -
(-) 		5 / 6 LEU B  31
HIS B 204
GLU B 251
HIS B 191
HIS B 193
 None
ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.48A 2ow9A-5xneB:
undetectable		 2ow9A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.86A 2ow9B-5xneB:
undetectable		 2ow9B-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.82A 2ozrC-5xneB:
undetectable		 2ozrC-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.86A 2ozrD-5xneB:
undetectable		 2ozrD-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.83A 2ozrE-5xneB:
undetectable		 2ozrE-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5xne -
(-) 		5 / 11 LEU B  32
LEU B  31
LEU B  59
ILE B 247
HIS B 193
 None
None
None
None
ZN  B 301 (-3.4A)
 1.22A 2qd3A-5xneB:
undetectable		 2qd3A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 5xne -
(-) 		3 / 3 PRO B  89
ASN B  57
ARG B  87
 None
 1.09A 2qeuB-5xneB:
undetectable		 2qeuB-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.83A 3kecA-5xneB:
undetectable		 3kecA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 5xne -
(-) 		5 / 5 LEU B  31
HIS B 204
GLU B 251
HIS B 191
HIS B 193
 None
ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.46A 3kecA-5xneB:
undetectable		 3kecA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.78A 3likA-5xneB:
undetectable		 3likA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.78A 3lilA-5xneB:
undetectable		 3lilA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.17A 3lilA-5xneB:
undetectable		 3lilA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.76A 3ljgA-5xneB:
undetectable		 3ljgA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.80A 3lkaA-5xneB:
undetectable		 3lkaA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5xne -
(-) 		5 / 12 VAL B 139
ILE B 130
VAL B 174
LEU B 192
VAL B 205
 None
 1.06A 3w68D-5xneB:
undetectable		 3w68D-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5xne -
(-) 		5 / 12 VAL B 139
PHE B 113
ILE B 130
LEU B 192
VAL B 205
 None
 1.05A 3w68D-5xneB:
undetectable		 3w68D-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 6 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.90A 4a7bA-5xneB:
undetectable		 4a7bA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 5xne -
(-) 		5 / 6 LEU B  31
HIS B 204
GLU B 251
HIS B 191
HIS B 193
 None
ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.45A 4a7bA-5xneB:
undetectable		 4a7bA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 5xne -
(-) 		4 / 5 LEU B  59
HIS B 193
GLU B  62
HIS B 204
 None
ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
 1.14A 4a7bB-5xneB:
undetectable		 4a7bB-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB6_C_VLBC503_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 5xne -
(-) 		5 / 12 VAL B  35
TYR B  36
PRO B  89
ILE B 247
ILE B 185
 None
 1.38A 4eb6B-5xneB:
undetectable
4eb6C-5xneB:
undetectable		 4eb6B-5xneB:
undetectable
4eb6C-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5xne -
(-) 		5 / 12 LEU B  32
LEU B  31
LEU B  59
ILE B 247
HIS B 193
 None
None
None
None
ZN  B 301 (-3.4A)
 1.17A 4f4dA-5xneB:
undetectable		 4f4dA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IV0_A_SAMA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5xne -
(-) 		5 / 12 VAL B 205
GLY B 171
GLY B 134
ILE B 173
ILE B 195
 None
 0.95A 4iv0A-5xneB:
undetectable		 4iv0A-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5xne -
(-) 		4 / 5 TYR B  71
GLY B  68
ASP B  50
VAL B  25
 None
 1.05A 4nkvD-5xneB:
undetectable		 4nkvD-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.79A 5n5jA-5xneB:
undetectable		 5n5jA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 4 HIS B 204
GLU B 251
HIS B 191
HIS B 193
 ZN  B 301 (-3.3A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.5A)
ZN  B 301 (-3.4A)
 1.17A 5n5jA-5xneB:
undetectable		 5n5jA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 5xne -
(-) 		4 / 5 HIS B 193
GLU B  62
HIS B 204
HIS B 191
 ZN  B 301 (-3.4A)
ZN  B 301 ( 4.5A)
ZN  B 301 (-3.3A)
ZN  B 301 (-3.5A)
 0.80A 5n5kA-5xneB:
undetectable		 5n5kA-5xneB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5xne -
(-) 		4 / 5 LEU B 225
ILE B  64
MET B  28
GLY B 184
 None
 0.91A 6hd6A-5xneB:
undetectable		 6hd6A-5xneB:
undetectable