SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xp0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5xp0 PROBABLE CSGAB
OPERON
TRANSCRIPTIONAL
REGULATORY PROTEIN
(Salmonella
enterica) 		4 / 8 ILE A 124
LEU A  57
LEU A  87
PHE A 108
 None
 0.90A 2vctC-5xp0A:
undetectable		 2vctC-5xp0A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5xp0 PROBABLE CSGAB
OPERON
TRANSCRIPTIONAL
REGULATORY PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 121
GLN A 122
PHE A 108
LEU A  85
 None
 1.00A 3ag2C-5xp0A:
undetectable		 3ag2C-5xp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5xp0 PROBABLE CSGAB
OPERON
TRANSCRIPTIONAL
REGULATORY PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 121
GLN A 122
PHE A 108
LEU A  85
 None
 0.97A 3ag2P-5xp0A:
undetectable
3ag2W-5xp0A:
undetectable		 3ag2P-5xp0A:
undetectable
3ag2W-5xp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5xp0 PROBABLE CSGAB
OPERON
TRANSCRIPTIONAL
REGULATORY PROTEIN
(Salmonella
enterica) 		4 / 7 LEU A 121
GLN A 122
PHE A 108
LEU A  85
 None
 0.93A 3asnC-5xp0A:
undetectable
3asnJ-5xp0A:
undetectable		 3asnC-5xp0A:
undetectable
3asnJ-5xp0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5xp0 PROBABLE CSGAB
OPERON
TRANSCRIPTIONAL
REGULATORY PROTEIN
(Salmonella
enterica) 		4 / 6 ILE A  55
ILE A  68
TRP A  71
MET A  58
 None
 1.19A 3weoA-5xp0A:
2.0		 3weoA-5xp0A:
6.35