SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xpd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		4 / 7 ASN A 236
THR A 250
GLY A 240
ASP A 241
 None
 0.92A 1bu5A-5xpdA:
undetectable		 1bu5A-5xpdA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_B_ACRB820_1
(ALPHA-AMYLASE, SUSG)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		4 / 7 TYR A 235
GLU A 238
TRP A 259
LYS A 268
 None
 1.38A 3k8mB-5xpdA:
undetectable		 3k8mB-5xpdA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.19A 4e47A-5xpdA:
undetectable		 4e47A-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
ALA A  77
GLY A  79
GLU A  83
GLY A  16
 None
 1.30A 4e47B-5xpdA:
undetectable		 4e47B-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.17A 4e47B-5xpdA:
undetectable		 4e47B-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.20A 4e47C-5xpdA:
undetectable		 4e47C-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
ALA A  77
GLY A  79
GLU A  83
GLY A  16
 None
 1.28A 4jdsA-5xpdA:
undetectable		 4jdsA-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.17A 4jdsA-5xpdA:
undetectable		 4jdsA-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
ALA A  77
GLY A  79
GLU A  83
GLY A  16
 None
 1.28A 4jdsB-5xpdA:
undetectable		 4jdsB-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.17A 4jdsB-5xpdA:
undetectable		 4jdsB-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
ALA A  77
GLY A  79
GLU A  83
GLY A  16
 None
 1.32A 4jdsC-5xpdA:
undetectable		 4jdsC-5xpdA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5xpd SUGAR TRANSPORTER
(Arabidopsis
thaliana) 		5 / 11 ILE A  59
GLY A  79
GLU A  83
GLY A  16
ASN A 176
 None
None
None
None
DCM  A 301 (-4.1A)
 1.16A 4jdsC-5xpdA:
undetectable		 4jdsC-5xpdA:
23.53