SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xpg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 10 LEU A 460
ALA A 333
ASP A 332
VAL A 463
GLY A 646
 None
 1.20A 1d4sA-5xpgA:
undetectable		 1d4sA-5xpgA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 HIS A 637
LEU A 641
LEU A 638
PRO A 653
 None
 1.07A 1hz4A-5xpgA:
undetectable		 1hz4A-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K4T_D_TTCD990_1
(DNA TOPOISOMERASE I)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 GLU A 441
ARG A 335
LYS A 329
ASP A 332
 None
 1.37A 1k4tA-5xpgA:
undetectable		 1k4tA-5xpgA:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 11 LEU A 556
LEU A 523
ALA A 471
VAL A 519
TYR A 568
 None
 1.41A 1kt6A-5xpgA:
undetectable		 1kt6A-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_1
(NEURAMINIDASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 651
ARG A 661
ARG A 615
 None
 1.05A 1l7fA-5xpgA:
undetectable		 1l7fA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7H_A_BCZA801_1
(NEURAMINIDASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 651
ARG A 661
ARG A 615
 None
 1.08A 1l7hA-5xpgA:
undetectable		 1l7hA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RR8_A_TTCA100_1
(DNA TOPOISOMERASE I)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 GLU A 441
ARG A 335
LYS A 329
ASP A 332
 None
 1.32A 1rr8C-5xpgA:
undetectable		 1rr8C-5xpgA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RRJ_B_TTCB990_1
(DNA TOPOISOMERASE I)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 GLU A 441
ARG A 335
LYS A 329
ASP A 332
 None
 1.36A 1rrjA-5xpgA:
undetectable		 1rrjA-5xpgA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 8 LEU A 455
GLY A 453
LEU A 346
PRO A 431
 None
 0.96A 1ya4A-5xpgA:
undetectable		 1ya4A-5xpgA:
10.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 473
ALA A 474
LEU A 523
LEU A 570
THR A 626
 None
 1.25A 2aa6B-5xpgA:
undetectable		 2aa6B-5xpgA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 174
LEU A 270
TRP A 128
GLY A 149
LEU A 279
 None
 1.07A 2aylB-5xpgA:
undetectable		 2aylB-5xpgA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 7 SER A 110
ARG A  17
LEU A  19
GLU A  23
 None
 0.97A 2cdqB-5xpgA:
undetectable		 2cdqB-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 10 LEU A 617
LEU A 619
LEU A 544
ASN A 546
ARG A 651
 None
 1.33A 2ceoB-5xpgA:
undetectable		 2ceoB-5xpgA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 7 LEU A 638
THR A 639
PRO A 653
GLY A 591
 None
 0.82A 2ddwB-5xpgA:
undetectable		 2ddwB-5xpgA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 9 LEU A 179
THR A 258
HIS A 256
HIS A 227
LEU A 204
 None
 1.47A 2jihA-5xpgA:
3.8		 2jihA-5xpgA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 473
ALA A 474
LEU A 523
LEU A 570
THR A 626
 None
 1.27A 2oaxB-5xpgA:
undetectable		 2oaxB-5xpgA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 473
ALA A 474
LEU A 523
LEU A 570
THR A 626
 None
 1.23A 2oaxF-5xpgA:
undetectable		 2oaxF-5xpgA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 HIS A 607
PRO A 614
TYR A 582
PRO A 583
 SO4  A 701 (-4.1A)
None
None
None
 1.32A 2ombA-5xpgA:
undetectable
2ombB-5xpgA:
undetectable		 2ombA-5xpgA:
undetectable
2ombB-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 7 HIS A 607
PRO A 614
TYR A 582
PRO A 583
 SO4  A 701 (-4.1A)
None
None
None
 1.27A 2ombC-5xpgA:
undetectable
2ombD-5xpgA:
undetectable		 2ombC-5xpgA:
undetectable
2ombD-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 7 TYR A 582
PRO A 583
HIS A 607
PRO A 614
 None
None
SO4  A 701 (-4.1A)
None
 1.27A 2ombC-5xpgA:
undetectable
2ombD-5xpgA:
undetectable		 2ombC-5xpgA:
undetectable
2ombD-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 9 PHE A 163
LEU A  24
PRO A  26
LEU A 112
ALA A 113
 None
 1.21A 2vcvD-5xpgA:
undetectable		 2vcvD-5xpgA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 9 PHE A 163
LEU A  24
PRO A  26
LEU A 112
ALA A 113
 None
 1.13A 2vcvE-5xpgA:
undetectable		 2vcvE-5xpgA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 9 PHE A 163
LEU A  24
PRO A  26
LEU A 112
ALA A 113
 None
 1.15A 2vcvH-5xpgA:
undetectable		 2vcvH-5xpgA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 VAL A 193
VAL A 262
THR A 201
ARG A 194
 None
 1.17A 3bjwA-5xpgA:
undetectable		 3bjwA-5xpgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 5 VAL A 193
VAL A 262
THR A 201
ARG A 194
 None
 1.20A 3bjwC-5xpgA:
undetectable		 3bjwC-5xpgA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 HIS A 227
LEU A 257
ALA A 242
PRO A 255
 None
 1.32A 3gv1A-5xpgA:
undetectable
3gv1C-5xpgA:
undetectable		 3gv1A-5xpgA:
undetectable
3gv1C-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 257
ALA A 242
PRO A 255
HIS A 227
 None
 1.33A 3gv1A-5xpgA:
undetectable
3gv1B-5xpgA:
undetectable		 3gv1A-5xpgA:
undetectable
3gv1B-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 GLN A 433
GLY A 453
LEU A 460
LEU A 451
ALA A 405
 None
 0.96A 3kkzA-5xpgA:
undetectable		 3kkzA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 TYR A 568
GLY A 624
ASP A 625
 None
 0.69A 3ou6C-5xpgA:
undetectable		 3ou6C-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 501
ALA A 490
THR A 504
LEU A 473
 None
 1.00A 3t3zB-5xpgA:
undetectable		 3t3zB-5xpgA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 501
ALA A 490
THR A 504
LEU A 473
 None
 1.00A 3t3zD-5xpgA:
undetectable		 3t3zD-5xpgA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 SER A 178
LEU A 260
HIS A 227
THR A 258
 None
 1.47A 3thrB-5xpgA:
undetectable		 3thrB-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 527
GLY A 476
THR A 526
LEU A 473
GLY A 488
 None
 1.02A 3uq6A-5xpgA:
undetectable		 3uq6A-5xpgA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 527
GLY A 476
THR A 526
LEU A 473
GLY A 488
 None
 1.06A 3uq6B-5xpgA:
undetectable		 3uq6B-5xpgA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 527
GLY A 476
THR A 526
LEU A 473
GLY A 488
 None
 1.01A 3vaqA-5xpgA:
undetectable		 3vaqA-5xpgA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 527
GLY A 476
THR A 526
LEU A 473
GLY A 488
 None
 1.06A 3vaqB-5xpgA:
undetectable		 3vaqB-5xpgA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 527
GLY A 476
THR A 526
LEU A 473
GLY A 488
 None
 1.03A 3vasA-5xpgA:
undetectable		 3vasA-5xpgA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 4 LEU A 619
LEU A 604
GLN A 634
GLU A 629
 None
 1.26A 4i41A-5xpgA:
2.5		 4i41A-5xpgA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 418
ASP A 417
ARG A 420
 None
 0.62A 4wq4B-5xpgA:
3.2		 4wq4B-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 TYR A 171
ARG A 286
GLY A 612
LEU A 281
 None
 1.00A 5bphA-5xpgA:
6.0		 5bphA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 PRO A 330
LEU A 455
SER A 645
 None
 0.83A 5fsaB-5xpgA:
undetectable		 5fsaB-5xpgA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 174
LEU A 270
TRP A 128
GLY A 149
LEU A 279
 None
 1.11A 5ikrB-5xpgA:
undetectable		 5ikrB-5xpgA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 473
ASP A 497
GLY A 499
LEU A 502
ALA A 529
 None
 1.26A 5kbwA-5xpgA:
undetectable		 5kbwA-5xpgA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 473
ASP A 497
GLY A 499
LEU A 502
ALA A 529
 None
 1.27A 5kc4E-5xpgA:
undetectable		 5kc4E-5xpgA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 8 LEU A 523
ALA A 471
VAL A 519
TYR A 568
 None
 0.97A 5nu7A-5xpgA:
undetectable		 5nu7A-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 117
ARG A 299
THR A 305
LEU A  16
 None
 1.05A 5x1fA-5xpgA:
undetectable
5x1fJ-5xpgA:
undetectable		 5x1fA-5xpgA:
undetectable
5x1fJ-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 ARG A 335
PHE A 647
ARG A 444
 None
C  G  19 ( 4.7A)
G  G  20 ( 4.4A)
 1.08A 5y9yA-5xpgA:
undetectable		 5y9yA-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 ASP A 332
PHE A 647
ARG A 444
 None
C  G  19 ( 4.7A)
G  G  20 ( 4.4A)
 1.11A 5yw0A-5xpgA:
undetectable		 5yw0A-5xpgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		5 / 12 VAL A 685
PRO A 319
PHE A 636
PRO A 655
ILE A 635
 None
 1.22A 6becA-5xpgA:
undetectable
6becB-5xpgA:
undetectable
6becC-5xpgA:
undetectable		 6becA-5xpgA:
10.02
6becB-5xpgA:
10.02
6becC-5xpgA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5xpg UNCHARACTERIZED
PROTEIN
(Thermus
thermophilus) 		3 / 3 LEU A 638
ASN A 546
LEU A 617
 None
 0.71A 6exiD-5xpgA:
undetectable		 6exiD-5xpgA:
29.07