SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xpw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK1_A_T44A3004_1 (SERUM ALBUMIN)	5xpw	AMPHIOXUS IGVJ-C2 (Branchiostoma floridae)	4 / 6	GLU A 63 LEU A 62 VAL A 33 MET A 34	None	1.08A	1hk1A-5xpwA: undetectable	1hk1A-5xpwA: 9.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_D_RIMD499_1 (MATRIX PROTEIN 2)	5xpw	AMPHIOXUS IGVJ-C2 (Branchiostoma floridae)	4 / 6	ILE A 64 ARG A 68 LEU A 67 LEU A 48	None	0.85A	2rlfA-5xpwA: undetectable 2rlfD-5xpwA: undetectable	2rlfA-5xpwA: 16.00 2rlfD-5xpwA: 16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G19_D_ACTD302_0 (GLUTATHIONE TRANSFERASE GTE1)	5xpw	AMPHIOXUS IGVJ-C2 (Branchiostoma floridae)	3 / 3	TYR A 22 PHE A 56 ARG A 60	None	1.15A	4g19D-5xpwA: undetectable	4g19D-5xpwA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	5xpw	AMPHIOXUS IGVJ-C2 (Branchiostoma floridae)	4 / 6	PHE A 56 MET A 34 ARG A 60 VAL A 79	None	1.37A	4mk4B-5xpwA: undetectable	4mk4B-5xpwA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK1_A_T44A3004_1","SERUM ALBUMIN","5xpw","AMPHIOXUS IGVJ-C2","Branchiostoma floridae",4,"GLU A  63;LEU A  62;VAL A  33;MET A  34","None","1.08A","1hk1A-5xpwA:undetectable","1hk1A-5xpwA:9.86"],["2RLF_D_RIMD499_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","5xpw","AMPHIOXUS IGVJ-C2","Branchiostoma floridae",4,"ILE A  64;ARG A  68;LEU A  67;LEU A  48","None","0.85A","2rlfA-5xpwA:undetectable;2rlfD-5xpwA:undetectable","2rlfA-5xpwA:16.00;2rlfD-5xpwA:16.00"],["4G19_D_ACTD302_0","GLUTATHIONE TRANSFERASE GTE1","5xpw","AMPHIOXUS IGVJ-C2","Branchiostoma floridae",3,"TYR A  22;PHE A  56;ARG A  60","None","1.15A","4g19D-5xpwA:undetectable","4g19D-5xpwA:undetectable"],["4MK4_B_CHDB502_0","FERROCHELATASE, MITOCHONDRIAL","5xpw","AMPHIOXUS IGVJ-C2","Branchiostoma floridae",4,"PHE A  56;MET A  34;ARG A  60;VAL A  79","None","1.37A","4mk4B-5xpwA:undetectable","4mk4B-5xpwA:undetectable"]]