SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xpz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		5 / 10 ALA A  86
ALA A  88
LEU A  90
LEU A  20
VAL A  35
 None
 0.95A 2bxeA-5xpzA:
3.1		 2bxeA-5xpzA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		5 / 10 ALA A  86
ALA A  88
LEU A  90
LEU A  20
VAL A  35
 None
 1.02A 2bxgB-5xpzA:
3.6		 2bxgB-5xpzA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		5 / 12 CYH A 127
HIS A 134
LEU A 140
PHE A 120
LEU A 667
 None
 1.33A 3adsA-5xpzA:
undetectable		 3adsA-5xpzA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		4 / 7 PHE A 609
ILE A 588
SER A 278
TYR A 590
 None
 0.97A 3pglA-5xpzA:
undetectable		 3pglA-5xpzA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		4 / 8 ARG A 576
GLU A 583
GLU A 584
ARG A 595
 None
 1.25A 4bqfB-5xpzA:
undetectable		 4bqfB-5xpzA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		5 / 11 VAL A  24
VAL A  31
VAL A  22
TRP A  58
LEU A  52
 None
 1.08A 5e4dB-5xpzA:
undetectable		 5e4dB-5xpzA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xpz FERMITIN FAMILY
HOMOLOG 2
(Mus
musculus) 		4 / 4 LEU A 593
ARG A 595
ILE A 586
PHE A 636
 None
 1.34A 5kirB-5xpzA:
undetectable		 5kirB-5xpzA:
21.78