SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xqo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 PHE A 557
HIS A 255
LEU A 236
HIS A 224
 None
 1.06A 1azmA-5xqoA:
undetectable		 1azmA-5xqoA:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB6_0
(GRAMICIDIN A)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 TRP A 402
ALA A 291
VAL A 293
 None
 0.91A 1bdwA-5xqoA:
undetectable
1bdwB-5xqoA:
undetectable		 1bdwA-5xqoA:
undetectable
1bdwB-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETA_1_T441128_1
(TRANSTHYRETIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 5 LEU A 672
GLU A 724
ALA A 717
LEU A 675
 None
 1.16A 1eta1-5xqoA:
undetectable		 1eta1-5xqoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 6 LEU A 672
GLU A 724
ALA A 717
LEU A 675
 None
 1.12A 1etb1-5xqoA:
undetectable		 1etb1-5xqoA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 TRP A  89
LEU A 504
GLY A  47
LEU A 661
 None
 0.82A 1gtiB-5xqoA:
1.4		 1gtiB-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 TRP A  89
LEU A 504
GLY A  47
LEU A 661
 None
 0.78A 1gtiD-5xqoA:
1.4		 1gtiD-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 TRP A  89
LEU A 504
GLY A  47
LEU A 661
 None
 0.80A 1gtiE-5xqoA:
1.4		 1gtiE-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 LEU A 661
ALA A  29
ALA A 506
LEU A  34
HIS A  92
 None
 1.41A 1iiuA-5xqoA:
undetectable		 1iiuA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 421
ALA A 291
ALA A 384
VAL A 276
MET A 498
 None
 1.34A 1kt4A-5xqoA:
undetectable		 1kt4A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 661
ALA A  29
ALA A 506
LEU A  34
HIS A  92
 None
 1.38A 1kt5A-5xqoA:
undetectable		 1kt5A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 9 LEU A 592
TYR A 654
VAL A 786
GLY A 788
SER A 713
 None
 1.25A 1pxxB-5xqoA:
undetectable		 1pxxB-5xqoA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 10 LEU A 592
TYR A 654
VAL A 786
GLY A 788
SER A 713
 None
 1.27A 1pxxD-5xqoA:
undetectable		 1pxxD-5xqoA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 GLN A  99
ILE A 100
TYR A 101
 None
 0.59A 1vifA-5xqoA:
undetectable		 1vifA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 ASP A 711
GLU A 587
ARG A 845
 None
ADA  A1004 ( 3.7A)
None
 0.81A 1wopA-5xqoA:
undetectable		 1wopA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 THR A 858
GLU A 825
HIS A 820
 None
 0.88A 1xwfA-5xqoA:
undetectable		 1xwfA-5xqoA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 THR A 858
GLU A 825
HIS A 820
 None
 0.90A 1xwfB-5xqoA:
undetectable		 1xwfB-5xqoA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 THR A 858
GLU A 825
HIS A 820
 None
 0.88A 1xwfC-5xqoA:
undetectable		 1xwfC-5xqoA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 THR A 858
GLU A 825
HIS A 820
 None
 0.88A 1xwfD-5xqoA:
undetectable		 1xwfD-5xqoA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ILE A 204
HIS A 224
GLY A 202
PHE A 238
GLY A 271
 None
 1.10A 1zz1C-5xqoA:
undetectable		 1zz1C-5xqoA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA996_1
(GLUCOAMYLASE GLU1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 HIS A 635
ASP A 903
GLY A 580
TYR A 581
 ADA  A1004 ( 4.1A)
None
None
None
 0.99A 2f6dA-5xqoA:
5.5		 2f6dA-5xqoA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 ASN A 172
ARG A 273
GLU A 420
VAL A 156
 None
 0.90A 2fl5E-5xqoA:
undetectable
2fl5F-5xqoA:
0.9		 2fl5E-5xqoA:
20.35
2fl5F-5xqoA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 6 LEU A 278
ILE A 288
VAL A 302
ALA A 414
 None
 0.97A 2j5mA-5xqoA:
undetectable		 2j5mA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 9 VAL A 218
THR A 216
VAL A 132
ASP A 134
VAL A 141
 None
 1.03A 2l8mA-5xqoA:
undetectable		 2l8mA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 THR A 738
ALA A 745
ALA A 811
PHE A 751
ILE A 797
 None
 1.13A 2nyrA-5xqoA:
undetectable		 2nyrA-5xqoA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 244
VAL A 141
ILE A 161
PHE A 274
PHE A 150
 None
 1.24A 2weyA-5xqoA:
undetectable		 2weyA-5xqoA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 GLU A 666
TYR A 243
ARG A 215
SER A 662
 None
 0.90A 2zt7A-5xqoA:
undetectable		 2zt7A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 5 LEU A  64
GLN A 103
HIS A  92
LEU A  48
 None
 1.10A 3ce6D-5xqoA:
undetectable		 3ce6D-5xqoA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 TYR A 660
TYR A 799
GLY A  80
 None
 0.49A 3eteB-5xqoA:
undetectable
3eteD-5xqoA:
undetectable
3eteF-5xqoA:
undetectable		 3eteB-5xqoA:
10.31
3eteD-5xqoA:
10.31
3eteF-5xqoA:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 1.00A 3g88A-5xqoA:
undetectable		 3g88A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 1.00A 3g88B-5xqoA:
undetectable		 3g88B-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 1.00A 3g89A-5xqoA:
undetectable		 3g89A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 1.01A 3g89B-5xqoA:
undetectable		 3g89B-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 0.99A 3g8bA-5xqoA:
undetectable		 3g8bA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLY A 718
GLY A 714
ALA A 733
GLU A 732
ARG A 655
 None
 1.05A 3g8bB-5xqoA:
undetectable		 3g8bB-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L4D_D_TPFD490_1
(STEROL 14-ALPHA
DEMETHYLASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 TYR A 510
ALA A 108
THR A  60
LEU A  87
 None
 1.04A 3l4dD-5xqoA:
undetectable		 3l4dD-5xqoA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 1.06A 3tbgA-5xqoA:
undetectable		 3tbgA-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_B_RTZB1_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 1.03A 3tbgB-5xqoA:
undetectable		 3tbgB-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 1.04A 3tbgC-5xqoA:
undetectable		 3tbgC-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_D_RTZD1_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 1.07A 3tbgD-5xqoA:
undetectable		 3tbgD-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLY A 718
GLY A 714
TYR A 654
ALA A 733
LEU A 676
 None
 1.19A 3vywD-5xqoA:
undetectable		 3vywD-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 6 SER A 586
ASP A 584
THR A 633
ILE A 649
 None
 0.86A 4acbC-5xqoA:
undetectable		 4acbC-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 LYS A 604
TYR A 607
ARG A 608
 None
 0.96A 4gc9A-5xqoA:
undetectable		 4gc9A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 5 PRO A 768
ASP A 771
ASN A 777
VAL A 832
 None
 1.39A 4hytA-5xqoA:
undetectable		 4hytA-5xqoA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 HIS A 565
ASN A 902
ASP A 642
ILE A 649
 None
RAM  A1003 ( 4.1A)
None
None
 0.89A 4k0bA-5xqoA:
undetectable		 4k0bA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 9 GLY A 766
PHE A 706
LEU A 708
SER A 705
GLY A 754
 None
 1.34A 4kqiA-5xqoA:
undetectable		 4kqiA-5xqoA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ALA A 716
TRP A 719
PHE A 706
SER A 755
LEU A 747
 None
 1.42A 4kyaB-5xqoA:
undetectable		 4kyaB-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_D_FOLD703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ALA A 716
TRP A 719
PHE A 706
SER A 755
LEU A 747
 None
 1.40A 4kyaD-5xqoA:
undetectable		 4kyaD-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_F_FOLF703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ALA A 716
TRP A 719
PHE A 706
SER A 755
LEU A 747
 None
 1.40A 4kyaF-5xqoA:
undetectable		 4kyaF-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_H_FOLH703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ALA A 716
TRP A 719
PHE A 706
SER A 755
LEU A 747
 None
 1.42A 4kyaH-5xqoA:
undetectable		 4kyaH-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 HIS A 565
ASN A 902
ASP A 642
ILE A 649
 None
RAM  A1003 ( 4.1A)
None
None
 0.83A 4l7iA-5xqoA:
undetectable		 4l7iA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 ARG A 404
GLU A 611
ARG A 473
 None
 1.00A 4mwvA-5xqoA:
undetectable		 4mwvA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 8 THR A 681
LEU A 715
VAL A 704
SER A 705
 None
 1.14A 4qknA-5xqoA:
1.8		 4qknA-5xqoA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvmV-5xqoA:
undetectable
4qvmb-5xqoA:
undetectable		 4qvmV-5xqoA:
16.52
4qvmb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvmH-5xqoA:
undetectable
4qvmN-5xqoA:
undetectable		 4qvmH-5xqoA:
16.52
4qvmN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvnV-5xqoA:
undetectable
4qvnb-5xqoA:
undetectable		 4qvnV-5xqoA:
16.52
4qvnb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvnH-5xqoA:
undetectable
4qvnN-5xqoA:
undetectable		 4qvnH-5xqoA:
16.52
4qvnN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvqV-5xqoA:
undetectable
4qvqb-5xqoA:
undetectable		 4qvqV-5xqoA:
16.52
4qvqb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 4qvqH-5xqoA:
undetectable
4qvqN-5xqoA:
undetectable		 4qvqH-5xqoA:
16.52
4qvqN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 10 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.18A 4qvvV-5xqoA:
undetectable
4qvvb-5xqoA:
undetectable		 4qvvV-5xqoA:
16.52
4qvvb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 10 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvvH-5xqoA:
undetectable
4qvvN-5xqoA:
undetectable		 4qvvH-5xqoA:
16.52
4qvvN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qvwV-5xqoA:
undetectable
4qvwb-5xqoA:
undetectable		 4qvwV-5xqoA:
16.52
4qvwb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 4qvwH-5xqoA:
undetectable
4qvwN-5xqoA:
undetectable		 4qvwH-5xqoA:
16.52
4qvwN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.17A 4qw0V-5xqoA:
undetectable
4qw0b-5xqoA:
undetectable		 4qw0V-5xqoA:
16.52
4qw0b-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 4qw0H-5xqoA:
undetectable
4qw0N-5xqoA:
undetectable		 4qw0H-5xqoA:
16.52
4qw0N-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 4qw1H-5xqoA:
undetectable
4qw1N-5xqoA:
undetectable		 4qw1H-5xqoA:
16.52
4qw1N-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.17A 4qw3V-5xqoA:
undetectable
4qw3b-5xqoA:
undetectable		 4qw3V-5xqoA:
16.52
4qw3b-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.18A 4qw3H-5xqoA:
undetectable
4qw3N-5xqoA:
undetectable		 4qw3H-5xqoA:
16.52
4qw3N-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 LYS A 690
TRP A 461
GLN A 450
 None
 1.33A 4qzuC-5xqoA:
0.5		 4qzuC-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLU A 587
ASN A 902
ASP A 903
ILE A 904
PHE A 544
 ADA  A1004 ( 3.7A)
RAM  A1003 ( 4.1A)
None
None
None
 1.09A 4u8yB-5xqoA:
undetectable		 4u8yB-5xqoA:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_A_QDNA602_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 0.98A 4wnuA-5xqoA:
undetectable		 4wnuA-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_C_QDNC602_1
(CYTOCHROME P450 2D6)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 LEU A 789
PHE A 706
GLY A 750
LEU A 747
SER A 755
 None
 0.94A 4wnuC-5xqoA:
undetectable		 4wnuC-5xqoA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 6 ILE A 157
VAL A 477
PHE A 274
THR A 422
 None
 1.13A 4xe5A-5xqoA:
undetectable		 4xe5A-5xqoA:
5.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 TYR A 385
VAL A 276
ILE A 161
LEU A 383
 None
 1.20A 4xo7B-5xqoA:
undetectable		 4xo7B-5xqoA:
10.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 ILE A 411
GLY A 387
THR A 485
LEU A 491
 None
 0.88A 4zdzA-5xqoA:
undetectable		 4zdzA-5xqoA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 7 ILE A 411
GLY A 387
THR A 485
LEU A 491
 None
 0.77A 4ze3A-5xqoA:
undetectable		 4ze3A-5xqoA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_B_DESB600_1
(ESTROGEN RECEPTOR)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 LEU A 386
ALA A 395
LEU A 491
LEU A 383
HIS A 287
 None
 1.31A 4zn7B-5xqoA:
undetectable		 4zn7B-5xqoA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_B_SAMB301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 GLY A 908
ILE A 541
LEU A 596
LEU A 538
ALA A 916
 None
 1.07A 5bw4B-5xqoA:
undetectable		 5bw4B-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 9 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 5cz7V-5xqoA:
undetectable
5cz7b-5xqoA:
undetectable		 5cz7V-5xqoA:
16.52
5cz7b-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 5cz7H-5xqoA:
undetectable
5cz7N-5xqoA:
undetectable		 5cz7H-5xqoA:
16.52
5cz7N-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.18A 5d0xV-5xqoA:
undetectable
5d0xb-5xqoA:
undetectable		 5d0xV-5xqoA:
16.52
5d0xb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 5d0xH-5xqoA:
undetectable
5d0xN-5xqoA:
undetectable		 5d0xH-5xqoA:
16.52
5d0xN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 6 ILE A 257
PHE A 238
THR A 422
TRP A 424
 None
 1.30A 5g08A-5xqoA:
undetectable		 5g08A-5xqoA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_1
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		6 / 12 GLY A 377
GLY A 360
ALA A 291
LEU A 409
PHE A 401
GLY A 408
 None
 1.29A 5hieC-5xqoA:
undetectable		 5hieC-5xqoA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 ILE A 316
GLY A 313
ASP A 285
GLU A 282
ILE A 343
 None
 1.32A 5igwA-5xqoA:
undetectable		 5igwA-5xqoA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.21A 5l5fV-5xqoA:
undetectable
5l5fb-5xqoA:
undetectable		 5l5fV-5xqoA:
16.52
5l5fb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.21A 5l5fH-5xqoA:
0.0
5l5fN-5xqoA:
undetectable		 5l5fH-5xqoA:
16.52
5l5fN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 5l5zV-5xqoA:
undetectable
5l5zb-5xqoA:
undetectable		 5l5zV-5xqoA:
16.52
5l5zb-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.20A 5l5zH-5xqoA:
undetectable
5l5zN-5xqoA:
undetectable		 5l5zH-5xqoA:
16.52
5l5zN-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 11 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.19A 5l66V-5xqoA:
undetectable
5l66b-5xqoA:
undetectable		 5l66V-5xqoA:
16.52
5l66b-5xqoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 GLY A  47
LEU A  48
HIS A  92
 None
 0.59A 5u63A-5xqoA:
undetectable		 5u63A-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 GLY A  47
LEU A  48
HIS A  92
 None
 0.60A 5u63B-5xqoA:
undetectable		 5u63B-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_1
(OXAC)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		4 / 5 HIS A 624
ASP A 621
ASP A 584
ARG A 667
 None
CA  A1001 (-2.1A)
None
None
 1.46A 5w7pA-5xqoA:
undetectable		 5w7pA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		3 / 3 MET A 254
ASP A 665
ARG A 608
 None
 1.06A 5z6kA-5xqoA:
undetectable		 5z6kA-5xqoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.13A 6hwdV-5xqoA:
undetectable
6hwdb-5xqoA:
undetectable		 6hwdV-5xqoA:
16.67
6hwdb-5xqoA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5xqo PCRGLX PROTEIN
(Penicillium
chrysogenum) 		5 / 12 SER A  26
THR A  90
THR A 105
ALA A 108
THR A  60
 None
 1.13A 6hwdH-5xqoA:
undetectable
6hwdN-5xqoA:
undetectable		 6hwdH-5xqoA:
16.67
6hwdN-5xqoA:
25.00