SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xqw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN
(Mus
musculus) 		4 / 5 LEU L 179
GLY L 128
PRO L 120
VAL L 132
 None
 0.90A 2aojA-5xqwL:
undetectable		 2aojA-5xqwL:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN
(Mus
musculus) 		5 / 12 TYR L  86
LEU L 104
GLU L  79
LEU L  78
ARG L  61
 None
 1.27A 2bxfB-5xqwL:
undetectable		 2bxfB-5xqwL:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, HEAVY CHAIN
FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN
(Mus
musculus;
Mus
musculus) 		4 / 8 MET L 175
LEU L 136
SER H 178
VAL L 159
 None
 1.00A 2qd2A-5xqwL:
undetectable		 2qd2A-5xqwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, HEAVY CHAIN
FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN
(Mus
musculus) 		3 / 3 VAL L  89
VAL H  93
SER H  95
 8EU  H 301 ( 4.8A)
8EU  H 301 ( 4.7A)
8EU  H 301 (-2.7A)
 0.52A 3n8xB-5xqwL:
undetectable		 3n8xB-5xqwL:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, LIGHT CHAIN
(Mus
musculus) 		4 / 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 0.93A 3tgvB-5xqwL:
undetectable		 3tgvB-5xqwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 5xqw FAB FRAGMENT OF
CATALYTIC ANTIBODY
7B9, HEAVY CHAIN
(Mus
musculus) 		5 / 12 GLY H 157
SER H 156
HIS H 164
VAL H 136
LEU H 138
 None
 1.18A 5ergB-5xqwH:
undetectable		 5ergB-5xqwH:
undetectable