SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 PHE A  38
LEU A  29
SER A 156
 GNP  A 301 (-4.8A)
None
GNP  A 301 (-3.3A)
 0.68A 1e7aA-5xr6A:
undetectable		 1e7aA-5xr6A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		5 / 12 LEU A 123
ALA A 104
PHE A 101
GLY A 125
ILE A  92
 None
 1.15A 1kglA-5xr6A:
undetectable		 1kglA-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 GLY A  85
TRP A  67
VAL A  17
 None
 0.73A 3n62B-5xr6A:
undetectable		 3n62B-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 GLY A  85
TRP A  67
VAL A  17
 None
 0.74A 3n65B-5xr6A:
undetectable		 3n65B-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 GLY A  85
TRP A  67
VAL A  17
 None
 0.74A 3n66B-5xr6A:
undetectable		 3n66B-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		4 / 6 ASP A  21
GLY A  23
VAL A  24
ASP A  94
 None
GNP  A 301 (-3.4A)
GNP  A 301 (-4.1A)
None
 1.16A 3vqrA-5xr6A:
undetectable		 3vqrA-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		4 / 5 ASP A  21
GLY A  23
VAL A  24
ASP A  94
 None
GNP  A 301 (-3.4A)
GNP  A 301 (-4.1A)
None
 1.17A 3vqrB-5xr6A:
undetectable		 3vqrB-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 LYS A  76
THR A  79
ILE A  19
 None
 0.88A 4e0fB-5xr6A:
undetectable		 4e0fB-5xr6A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		5 / 12 PHE A  14
GLY A  88
ALA A  89
ILE A 177
TYR A  12
 None
 1.22A 4rtpA-5xr6A:
undetectable		 4rtpA-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		3 / 3 GLY A  85
TRP A  67
VAL A  17
 None
 0.75A 5vuoB-5xr6A:
undetectable		 5vuoB-5xr6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA413_0
(AROMATIC
PEROXYGENASE)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		4 / 7 ASP A 159
GLY A 125
SER A 156
VAL A  95
 None
None
GNP  A 301 (-3.3A)
None
 0.97A 6ekzA-5xr6A:
undetectable		 6ekzA-5xr6A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_A_STIA604_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5xr6 RAS-RELATED PROTEIN
RABA1A
(Arabidopsis
thaliana) 		4 / 5 VAL A  87
PHE A 152
MET A 153
GLY A 125
 None
 1.43A 6hd4A-5xr6A:
undetectable		 6hd4A-5xr6A:
22.73