SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xrw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 5xrw FLIN
FLIY
(Helicobacter
pylori;
Helicobacter
pylori) 		5 / 11 GLU A  51
PHE C 268
GLY A  53
GLU C 260
LEU C 247
 None
 1.39A 1mjqA-5xrwA:
undetectable
1mjqB-5xrwA:
undetectable		 1mjqA-5xrwA:
undetectable
1mjqB-5xrwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5xrw FLIN
FLIY
(Helicobacter
pylori;
Helicobacter
pylori) 		5 / 11 ASN C 213
VAL C 251
ILE C 270
ALA C 257
ASP A  82
 None
 1.50A 2iyfA-5xrwC:
undetectable		 2iyfA-5xrwC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 5xrw FLIN
FLIY
(Helicobacter
pylori) 		5 / 10 ILE A  90
GLY C 234
GLU A  94
ASN A 107
GLU A 108
 None
 1.45A 2piwA-5xrwA:
undetectable		 2piwA-5xrwA:
17.53