SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5xs5 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 7 PHE B 214
MET B 197
ILE B 240
VAL B  85
 None
 1.06A 3p6hA-5xs5B:
undetectable		 3p6hA-5xs5B:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 5xs5 GENOME POLYPROTEIN
(Enterovirus
A) 		5 / 11 GLY B 215
ALA B 177
VAL B 217
PRO B 155
ILE B 132
 None
 0.96A 4j4vA-5xs5B:
undetectable		 4j4vA-5xs5B:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5xs5 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 5 THR B  68
THR B 231
HIS B 118
LEU B 224
 None
 1.40A 4lvcA-5xs5B:
undetectable		 4lvcA-5xs5B:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 5xs5 GENOME POLYPROTEIN
(Enterovirus
A) 		4 / 5 THR B  68
THR B 231
HIS B 118
LEU B 224
 None
 1.40A 6gbnD-5xs5B:
undetectable		 6gbnD-5xs5B:
18.67