SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xs9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_2
(PHOSPHOLIPASE A2)		 5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Mycolicibacteriu
m
smegmatis) 		4 / 6 VAL A 107
GLN A 114
GLY A 116
LEU A 185
 None
 1.11A 3bjwE-5xs9A:
undetectable		 3bjwE-5xs9A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Mycolicibacteriu
m
smegmatis) 		3 / 3 THR A 171
ASP A  84
GLU A  77
 None
 0.78A 3qowA-5xs9A:
2.0		 3qowA-5xs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  24
THR A  13
ILE A  58
GLY A  52
 None
 0.85A 4l39B-5xs9A:
undetectable		 4l39B-5xs9A:
9.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ALA A 101
GLY A 103
SER A 105
GLY A  52
 None
 0.91A 5e26C-5xs9A:
undetectable
5e26D-5xs9A:
undetectable		 5e26C-5xs9A:
undetectable
5e26D-5xs9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5xs9 TETR FAMILY
TRANSCRIPTIONAL
REGULATOR
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ARG A 150
PHE A 143
ARG A 168
 None
 1.19A 5y9yA-5xs9A:
undetectable		 5y9yA-5xs9A:
undetectable