SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xse'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		4 / 6 VAL A 176
GLY A 177
ALA A 164
LEU A 168
 None
 0.78A 1e7bB-5xseA:
undetectable		 1e7bB-5xseA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		5 / 11 VAL A  42
ILE A 192
ALA A  25
ALA A  62
ALA A  31
 None
 1.06A 3mdtB-5xseA:
undetectable		 3mdtB-5xseA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		4 / 8 GLY A 123
ASP A 121
GLY A 119
VAL A 151
 None
 0.84A 4c5nC-5xseA:
2.9		 4c5nC-5xseA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		5 / 10 GLY A  65
ALA A  62
VAL A  64
GLU A  84
VAL A  42
 None
 1.18A 4da7A-5xseA:
undetectable		 4da7A-5xseA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		5 / 12 ILE A   4
LEU A 120
PRO A 155
PRO A 108
LEU A 107
 None
 1.29A 5xxiA-5xseA:
undetectable		 5xxiA-5xseA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		4 / 4 LEU A  75
ASP A  76
GLN A  79
VAL A 151
 None
 1.23A 6bzoF-5xseA:
undetectable		 6bzoF-5xseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 5xse KHG/KDPG ALDOLASE
(Zymomonas
mobilis) 		4 / 4 LEU A  75
ASP A  76
GLN A 102
VAL A 151
 None
 1.40A 6bzoF-5xseA:
undetectable		 6bzoF-5xseA:
undetectable