SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xst'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 5 LEU A 323
SER A 286
LEU A 265
GLY A 289
 None
 1.09A 1a4lB-5xstA:
undetectable		 1a4lB-5xstA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 7 HIS A 201
GLY A 202
TYR A 235
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.46A 1dmaA-5xstA:
6.0		 1dmaA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 6 HIS A 201
GLY A 202
TYR A 235
ALA A 237
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.38A 1dmaB-5xstA:
6.1		 1dmaB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 TYR A 133
GLU A 179
ASP A 304
 None
 0.70A 3bxoA-5xstA:
undetectable		 3bxoA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 12 GLY A 210
ILE A 234
HIS A 201
LEU A 259
LEU A 338
 None
None
8E6  A 401 (-3.5A)
None
None
 1.20A 3cs8A-5xstA:
undetectable		 3cs8A-5xstA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
LYS A 242
SER A 243
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.9A)
 1.33A 3u9hA-5xstA:
19.1		 3u9hA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.83A 3u9hA-5xstA:
19.1		 3u9hA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
 0.93A 3u9hA-5xstA:
19.1		 3u9hA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
SER A 243
TYR A 246
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
 0.37A 3u9hA-5xstA:
19.1		 3u9hA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
LYS A 242
SER A 243
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.9A)
 1.33A 3u9hB-5xstA:
19.1		 3u9hB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.80A 3u9hB-5xstA:
19.1		 3u9hB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
 0.97A 3u9hB-5xstA:
19.1		 3u9hB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
SER A 243
TYR A 246
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
 0.42A 3u9hB-5xstA:
19.1		 3u9hB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 6 HIS A 201
GLY A 202
TYR A 235
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.57A 4ae1A-5xstA:
6.6		 4ae1A-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 5 HIS A 201
GLY A 202
TYR A 235
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.58A 4ae1B-5xstA:
6.1		 4ae1B-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
LYS A 242
SER A 243
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.9A)
 1.32A 4bjcA-5xstA:
18.4		 4bjcA-5xstA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
ALA A 237
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.77A 4bjcA-5xstA:
18.4		 4bjcA-5xstA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
 0.94A 4bjcA-5xstA:
18.4		 4bjcA-5xstA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		6 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
SER A 243
TYR A 246
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
 0.35A 4bjcA-5xstA:
18.4		 4bjcA-5xstA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 TYR A  28
HIS A 248
ARG A 204
 None
 1.10A 4htfA-5xstA:
undetectable		 4htfA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 7 HIS A 201
GLY A 202
TYR A 235
ALA A 237
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.58A 4hyfA-5xstA:
20.1		 4hyfA-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.9A)
 0.88A 4hyfB-5xstA:
20.3		 4hyfB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.59A 4hyfB-5xstA:
20.3		 4hyfB-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		8 / 8 HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.56A 4hyfC-5xstA:
20.3		 4hyfC-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 12 MET A 103
LEU A 107
LEU A 108
ILE A  30
HIS A  81
 None
 1.17A 4j24B-5xstA:
undetectable		 4j24B-5xstA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 10 TYR A  76
THR A  77
LEU A  71
ALA A  48
ILE A  79
 None
 1.28A 4pe5A-5xstA:
undetectable
4pe5B-5xstA:
undetectable		 4pe5A-5xstA:
7.46
4pe5B-5xstA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_C_QELC939_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 10 TYR A  76
THR A  77
LEU A  71
ALA A  48
ILE A  79
 None
 1.26A 4pe5C-5xstA:
undetectable
4pe5D-5xstA:
undetectable		 4pe5C-5xstA:
7.46
4pe5D-5xstA:
6.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		10 / 11 GLN A  98
GLU A 102
HIS A 201
GLY A 202
TYR A 228
TYR A 235
ALA A 237
LYS A 242
TYR A 246
GLU A 327
 8E6  A 401 ( 4.7A)
8E6  A 401 (-4.2A)
8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.7A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.74A 4rv6A-5xstA:
52.5		 4rv6A-5xstA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		10 / 11 GLN A  98
GLU A 102
HIS A 201
GLY A 202
TYR A 235
ALA A 237
LYS A 242
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 ( 4.7A)
8E6  A 401 (-4.2A)
8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.62A 4rv6A-5xstA:
52.5		 4rv6A-5xstA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		11 / 11 GLN A  98
GLU A 102
HIS A 201
GLY A 202
TYR A 228
TYR A 235
ALA A 237
LYS A 242
SER A 243
TYR A 246
GLU A 327
 8E6  A 401 ( 4.7A)
8E6  A 401 (-4.2A)
8E6  A 401 (-3.5A)
8E6  A 401 (-3.9A)
8E6  A 401 (-3.7A)
8E6  A 401 (-4.1A)
8E6  A 401 (-3.5A)
8E6  A 401 (-4.3A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
8E6  A 401 (-3.9A)
 0.72A 4rv6B-5xstA:
52.7		 4rv6B-5xstA:
98.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		8 / 9 GLU A 102
ASP A 109
HIS A 201
SER A 203
ASN A 207
ILE A 211
SER A 243
TYR A 246
 8E6  A 401 (-4.2A)
None
8E6  A 401 (-3.5A)
None
None
None
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
 0.80A 5ha9B-5xstA:
49.2		 5ha9B-5xstA:
98.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HA9_B_TP0B406_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		7 / 9 HIS A 201
SER A 203
ASN A 207
ILE A 211
TYR A 235
SER A 243
TYR A 246
 8E6  A 401 (-3.5A)
None
None
None
8E6  A 401 (-4.1A)
8E6  A 401 (-2.6A)
8E6  A 401 (-3.4A)
 0.51A 5ha9B-5xstA:
49.2		 5ha9B-5xstA:
98.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 11 ARG A 196
GLY A 261
ASN A 337
ASP A 332
VAL A 330
 None
 1.37A 5hjiA-5xstA:
undetectable		 5hjiA-5xstA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		5 / 10 VAL A 143
LEU A 170
ALA A 150
SER A 147
THR A 160
 None
 1.43A 5mm4B-5xstA:
undetectable		 5mm4B-5xstA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		3 / 3 GLY A 266
LEU A 193
HIS A 285
 None
 0.69A 5u63B-5xstA:
undetectable		 5u63B-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 4 GLY A 261
LEU A 338
VAL A 336
GLU A 183
 None
 1.47A 5yw0A-5xstA:
undetectable		 5yw0A-5xstA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5xst POLY [ADP-RIBOSE]
POLYMERASE 1
(Homo
sapiens) 		4 / 6 LEU A 136
VAL A 172
PHE A  16
GLY A 210
 None
 0.95A 6hd4B-5xstA:
undetectable		 6hd4B-5xstA:
22.73