SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xu5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		4 / 5 GLN B  71
PHE B  72
TRP B  62
GLY B  56
 None
 1.42A 2qmzA-5xu5B:
undetectable
2qmzB-5xu5B:
undetectable		 2qmzA-5xu5B:
17.26
2qmzB-5xu5B:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		4 / 4 LEU B  86
ILE B  94
GLY B  56
PHE B  58
 None
 1.04A 4dc3A-5xu5B:
undetectable		 4dc3A-5xu5B:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		5 / 12 GLY B 119
SER B 118
ASP B 127
ILE B 128
PHE B 110
 None
 1.20A 4dx5B-5xu5B:
undetectable		 4dx5B-5xu5B:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		3 / 3 ARG B  66
ASP B  51
TRP B  62
 None
 1.04A 4xdqA-5xu5B:
undetectable		 4xdqA-5xu5B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		4 / 5 PHE B  58
ILE B  57
GLN B  98
ARG B  97
 None
 1.39A 5jm4A-5xu5B:
undetectable		 5jm4A-5xu5B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		4 / 4 PHE B  58
ILE B  57
GLN B  98
ARG B  97
 None
 1.38A 5jm4B-5xu5B:
undetectable		 5jm4B-5xu5B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 5xu5 ENDO-1,4-BETA-MANNAN
ASE
(Rhizopus
microsporus) 		5 / 12 PHE B  63
LEU B 120
SER B 100
SER B  52
THR B  77
 None
 1.47A 5v1tA-5xu5B:
undetectable		 5v1tA-5xu5B:
undetectable