SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5xua METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Comamonas
testosteroni) 		5 / 10 ARG A 135
ILE A  68
PRO A 117
GLU A 116
ILE A 115
 None
 1.15A 2dm6A-5xuaA:
undetectable
2dm6B-5xuaA:
undetectable		 2dm6A-5xuaA:
14.11
2dm6B-5xuaA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5xua METHYL-ACCEPTING
CHEMOTAXIS SENSORY
TRANSDUCER
(Comamonas
testosteroni) 		4 / 5 THR A  82
THR A 108
LEU A 176
LEU A 173
 None
 1.08A 4lvcB-5xuaA:
undetectable		 4lvcB-5xuaA:
10.88