SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xum'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5xum HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Thermotoga
maritima) 		4 / 7 LEU A 123
PHE A 122
THR A 147
LEU A 148
 None
 1.05A 2eikA-5xumA:
undetectable
2eikJ-5xumA:
undetectable		 2eikA-5xumA:
undetectable
2eikJ-5xumA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 5xum HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Thermotoga
maritima) 		5 / 11 ALA A  51
GLY A  44
ILE A   7
LEU A 104
SER A  94
 None
 0.81A 3dcmX-5xumA:
undetectable		 3dcmX-5xumA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 5xum HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Thermotoga
maritima) 		5 / 9 ALA A  55
TYR A 162
ILE A 165
GLY A  86
VAL A  68
 None
 1.14A 4r1zA-5xumA:
undetectable		 4r1zA-5xumA:
10.71