SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 8 PHE A  20
VAL A 173
THR A 132
VAL A  27
 None
 1.06A 1dz9A-5xuyA:
undetectable		 1dz9A-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 8 PHE A  20
VAL A 173
THR A 132
VAL A  27
 None
 1.04A 1o76B-5xuyA:
undetectable		 1o76B-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 8 PHE A  20
VAL A 173
THR A 132
VAL A  27
 None
 1.18A 1uyuA-5xuyA:
undetectable		 1uyuA-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_B_SAMB206_0
(UPF0217 PROTEIN
MJ1640)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 5 SER A  85
LEU A 161
GLY A 163
GLU A  83
 None
 1.11A 3aiaA-5xuyA:
1.8
3aiaB-5xuyA:
undetectable		 3aiaA-5xuyA:
undetectable
3aiaB-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 6 ILE A  17
ASP A  14
ARG A  10
GLY A 181
 None
 1.00A 4oltA-5xuyA:
undetectable		 4oltA-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 6 ILE A  17
ASP A  14
ARG A  10
GLY A 181
 None
 1.05A 4oltB-5xuyA:
undetectable		 4oltB-5xuyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 5xuy AUTOPHAGY-RELATED
PROTEIN 13
(Homo
sapiens) 		4 / 8 ILE A  17
ASP A  14
ARG A  10
GLY A 181
 None
 1.02A 5hwaA-5xuyA:
undetectable		 5hwaA-5xuyA:
undetectable