SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 9 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.36A 1pw7B-5xv9A:
undetectable		 1pw7B-5xv9A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 11 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.29A 1vhwA-5xv9A:
undetectable
1vhwD-5xv9A:
undetectable		 1vhwA-5xv9A:
16.10
1vhwD-5xv9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 11 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.25A 1vhwC-5xv9A:
undetectable
1vhwE-5xv9A:
undetectable		 1vhwC-5xv9A:
16.10
1vhwE-5xv9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 11 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.27A 1vhwA-5xv9A:
undetectable
1vhwD-5xv9A:
undetectable		 1vhwA-5xv9A:
16.10
1vhwD-5xv9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 11 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.29A 1vhwC-5xv9A:
undetectable
1vhwE-5xv9A:
undetectable		 1vhwC-5xv9A:
16.10
1vhwE-5xv9A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5xv9 COLD-SHOCK
DNA-BINDING DOMAIN
FAMILY PROTEIN
(Colwellia
psychrerythraea) 		5 / 10 SER A   2
GLY A   4
VAL A  49
GLU A  50
ILE A  18
 None
 1.18A 5i3cB-5xv9A:
undetectable		 5i3cB-5xv9A:
13.27