SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xvs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDW_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		5 / 10 VAL A 110
LEU A  98
PHE A  86
MET A  93
GLU A  61
 None
 1.21A 1fdwA-5xvsA:
8.3		 1fdwA-5xvsA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		5 / 9 ASN A 288
LEU A 223
ALA A 226
LEU A 227
LEU A 333
 None
 1.30A 1hwiA-5xvsA:
undetectable		 1hwiA-5xvsA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_A_ACTA2001_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 5 TYR A 275
SER A 289
SER A 291
THR A 208
 UDP  A 402 (-4.0A)
UDP  A 402 (-3.7A)
UDP  A 402 (-3.3A)
UDP  A 402 ( 4.5A)
 1.43A 1yvpA-5xvsA:
4.7		 1yvpA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 5 LEU A 124
LEU A  16
MET A  21
THR A 111
 None
 1.14A 2oaxD-5xvsA:
undetectable		 2oaxD-5xvsA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_B_AG2B671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 8 ILE A 272
LEU A 178
LEU A  16
GLY A  15
 UDP  A 402 (-4.6A)
None
None
None
 0.93A 2qqdB-5xvsA:
undetectable
2qqdC-5xvsA:
undetectable		 2qqdB-5xvsA:
21.62
2qqdC-5xvsA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 6 VAL A 286
ILE A 230
ILE A 207
LEU A 206
 None
 0.74A 3hegA-5xvsA:
undetectable		 3hegA-5xvsA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 7 GLN A 310
GLU A 155
ARG A 315
PRO A 350
 UDP  A 402 (-4.0A)
None
None
None
 1.40A 3ql6A-5xvsA:
undetectable		 3ql6A-5xvsA:
8.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 5 GLY A 102
ASP A 103
ARG A 104
GLN A 112
 None
 0.97A 3qx3B-5xvsA:
undetectable		 3qx3B-5xvsA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		3 / 3 HIS A 180
SER A 294
GLU A 295
 None
None
UDP  A 402 (-3.1A)
 0.76A 3s8pA-5xvsA:
undetectable		 3s8pA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 7 PRO A 240
VAL A 250
ALA A 252
PHE A 224
 None
 1.04A 4lb2A-5xvsA:
undetectable		 4lb2A-5xvsA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		3 / 3 GLU A 128
ARG A 139
GLN A 310
 None
None
UDP  A 402 (-4.0A)
 0.94A 4rtbA-5xvsA:
undetectable		 4rtbA-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 6 SER A 290
GLY A 354
ASP A 179
GLY A 352
 UDP  A 402 (-2.4A)
None
None
None
 0.97A 5cdpA-5xvsA:
undetectable
5cdpB-5xvsA:
2.8		 5cdpA-5xvsA:
9.59
5cdpB-5xvsA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		3 / 3 VAL A   6
LYS A   2
MET A   1
 None
 0.97A 5nknA-5xvsA:
undetectable		 5nknA-5xvsA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 8 GLY A 102
GLU A 106
ILE A 138
ASP A 135
 None
 0.99A 5vlmD-5xvsA:
undetectable		 5vlmD-5xvsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		4 / 6 GLY A 126
TYR A 156
LEU A 163
VAL A 170
 None
 0.85A 5x80A-5xvsA:
undetectable
5x80B-5xvsA:
undetectable		 5x80A-5xvsA:
18.52
5x80B-5xvsA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 5xvs GDP/UDP-N,N'-DIACETY
LBACILLOSAMINE
2-EPIMERASE
(HYDROLYZING)
(Acinetobacter
baumannii) 		5 / 11 GLU A  64
GLY A   9
ALA A  38
ALA A  36
ILE A  52
 None
 1.04A 5yk2A-5xvsA:
undetectable		 5yk2A-5xvsA:
undetectable