SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xvu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 7 HIS A 313
LEU A 217
SER A 216
ASP A 214
 None
 1.24A 1ismB-5xvuA:
undetectable		 1ismB-5xvuA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 6 ILE A  49
VAL A  57
ILE A  98
ILE A 156
 ATP  A 403 (-4.9A)
ATP  A 403 (-3.9A)
None
None
 0.58A 1uwhA-5xvuA:
21.9		 1uwhA-5xvuA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 7 ILE A  49
LYS A  72
LEU A  89
ILE A  98
ILE A 156
 ATP  A 403 (-4.9A)
ATP  A 403 (-3.2A)
None
None
None
 0.70A 1uwjA-5xvuA:
6.2		 1uwjA-5xvuA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 8 ASP A  18
GLY A 155
ASP A 149
TYR A  16
 None
 0.90A 2aouA-5xvuA:
undetectable		 2aouA-5xvuA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_A_MIXA539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		7 / 12 GLY A  50
VAL A  57
ALA A  70
ASP A 160
LYS A 162
ASN A 165
MET A 167
 ATP  A 403 (-3.4A)
ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
None
None
ATP  A 403 ( 4.7A)
ATP  A 403 ( 3.7A)
 0.91A 2fumA-5xvuA:
24.0		 2fumA-5xvuA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_1
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		7 / 12 GLY A  50
GLY A  52
VAL A  57
ALA A  70
LYS A 162
ASN A 165
MET A 167
 ATP  A 403 (-3.4A)
ATP  A 403 ( 3.9A)
ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
None
ATP  A 403 ( 4.7A)
ATP  A 403 ( 3.7A)
 0.89A 2fumD-5xvuA:
22.6		 2fumD-5xvuA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 7 VAL A  77
LYS A  81
SER A  55
LYS A  72
 None
ATP  A 403 (-3.4A)
ATP  A 403 (-2.8A)
ATP  A 403 (-3.2A)
 1.46A 2j9cA-5xvuA:
0.0
2j9cB-5xvuA:
undetectable
2j9cC-5xvuA:
undetectable		 2j9cA-5xvuA:
17.16
2j9cB-5xvuA:
17.16
2j9cC-5xvuA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 8 ILE A 208
LEU A 246
TYR A 261
GLY A 203
 None
 0.94A 2vdbA-5xvuA:
undetectable		 2vdbA-5xvuA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_B_ROFB902_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 12 HIS A 158
LEU A  89
ILE A 178
MET A 167
PHE A 117
 None
None
ATP  A 403 ( 4.5A)
ATP  A 403 ( 3.7A)
None
 1.48A 3g4lB-5xvuA:
undetectable		 3g4lB-5xvuA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		6 / 12 VAL A  57
ALA A  70
GLU A  85
LEU A  89
ILE A  99
HIS A 158
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
None
None
ATP  A 403 (-4.9A)
None
 0.55A 3gp0A-5xvuA:
25.8		 3gp0A-5xvuA:
28.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 12 ALA A  70
LYS A  72
GLU A  85
LEU A  89
ILE A  99
 ATP  A 403 (-3.4A)
ATP  A 403 (-3.2A)
None
None
ATP  A 403 (-4.9A)
 0.66A 3hecA-5xvuA:
25.0		 3hecA-5xvuA:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 12 VAL A  57
ALA A  70
LYS A  72
LEU A  89
ILE A  99
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
ATP  A 403 (-3.2A)
None
ATP  A 403 (-4.9A)
 0.72A 3hegA-5xvuA:
25.2		 3hegA-5xvuA:
29.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LFA_A_1N1A361_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 8 ALA A  70
LYS A  72
GLU A  85
LEU A 115
 ATP  A 403 (-3.4A)
ATP  A 403 (-3.2A)
None
None
 0.28A 3lfaA-5xvuA:
24.7		 3lfaA-5xvuA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_1
(P38A)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		6 / 12 GLY A  50
VAL A  57
ALA A  70
LYS A  72
LEU A  89
ILE A  99
 ATP  A 403 (-3.4A)
ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
ATP  A 403 (-3.2A)
None
ATP  A 403 (-4.9A)
 0.68A 3ohtA-5xvuA:
6.1		 3ohtA-5xvuA:
28.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		8 / 12 VAL A  57
ALA A  70
GLU A  85
LEU A  89
ILE A  99
PHE A 117
TYR A 119
HIS A 158
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
None
None
ATP  A 403 (-4.9A)
None
None
None
 0.72A 3rgfA-5xvuA:
8.8		 3rgfA-5xvuA:
25.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WAR_A_NIOA401_1
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		6 / 8 VAL A  57
LYS A  72
ILE A  99
PHE A 117
MET A 167
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
ATP  A 403 (-4.9A)
None
ATP  A 403 ( 3.7A)
ATP  A 403 ( 4.5A)
 0.42A 3warA-5xvuA:
47.2		 3warA-5xvuA:
62.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		6 / 12 VAL A  57
ALA A  70
GLU A  85
ILE A  88
ILE A  99
TYR A 119
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
None
None
ATP  A 403 (-4.9A)
None
 0.76A 4bkjA-5xvuA:
19.9		 4bkjA-5xvuA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 5 LYS A  72
LEU A  92
TYR A 119
ARG A 159
 ATP  A 403 (-3.2A)
None
None
SO4  A 401 (-3.0A)
 1.35A 4bkjB-5xvuA:
20.0		 4bkjB-5xvuA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		7 / 12 VAL A  57
ALA A  70
ILE A  99
ASP A 160
LYS A 162
ASN A 165
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
ATP  A 403 (-4.9A)
None
None
ATP  A 403 ( 4.7A)
ATP  A 403 ( 4.5A)
 0.69A 4i41A-5xvuA:
24.6		 4i41A-5xvuA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 6 ASP A 214
GLU A 184
VAL A 196
ALA A 197
 None
 1.04A 4nkvC-5xvuA:
undetectable		 4nkvC-5xvuA:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CSH_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 5 ARG A  84
ARG A 159
LEU A 182
ASN A 193
VAL A 196
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
None
 0.34A 5cshB-5xvuA:
46.6		 5cshB-5xvuA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CU6_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 4 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.30A 5cu6A-5xvuA:
46.6		 5cu6A-5xvuA:
62.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CVF_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 4 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.26A 5cvfA-5xvuA:
40.6		 5cvfA-5xvuA:
62.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 7 GLY A  50
GLY A  52
VAL A  57
LYS A  72
LEU A  74
 ATP  A 403 (-3.4A)
ATP  A 403 ( 3.9A)
ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
None
 0.74A 5izjA-5xvuA:
24.7		 5izjA-5xvuA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_B_ADNB401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 9 ILE A  49
GLY A  50
VAL A  57
ALA A  70
ILE A  99
 ATP  A 403 (-4.9A)
ATP  A 403 (-3.4A)
ATP  A 403 (-3.9A)
ATP  A 403 (-3.4A)
ATP  A 403 (-4.9A)
 0.39A 5lw1B-5xvuA:
11.6		 5lw1B-5xvuA:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 10 PRO A 163
LEU A 222
PRO A 319
ALA A 322
PHE A 328
 None
 1.25A 5m0oA-5xvuA:
undetectable		 5m0oA-5xvuA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 4 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.28A 5os7A-5xvuA:
47.4		 5os7A-5xvuA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS7_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 5 ARG A  84
ARG A 159
LEU A 182
ASN A 193
VAL A 196
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
None
 0.34A 5os7B-5xvuA:
47.5		 5os7B-5xvuA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OS8_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 5 LYS A  81
ARG A  84
ARG A 159
LEU A 182
ASN A 193
 ATP  A 403 (-3.4A)
SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.49A 5os8A-5xvuA:
46.6		 5os8A-5xvuA:
62.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSP_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 4 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.34A 5ospA-5xvuA:
46.9		 5ospA-5xvuA:
61.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OSR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 5 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.29A 5osrA-5xvuA:
46.3		 5osrA-5xvuA:
61.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OTR_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 5 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.28A 5otrA-5xvuA:
45.9		 5otrA-5xvuA:
61.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 7 GLY A 189
TYR A 261
ASP A 214
TYR A 215
 None
 1.20A 5vlmG-5xvuA:
undetectable		 5vlmG-5xvuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 8 VAL A  57
LYS A  72
PHE A 117
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
None
ATP  A 403 ( 4.5A)
 0.25A 5y9mX-5xvuA:
45.9		 5y9mX-5xvuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_B_NIOB401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 7 VAL A  57
LYS A  72
PHE A 117
MET A 167
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
None
ATP  A 403 ( 3.7A)
ATP  A 403 ( 4.5A)
 0.87A 5yf9B-5xvuA:
45.5		 5yf9B-5xvuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF9_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		6 / 9 VAL A  57
LYS A  72
ILE A  99
PHE A 117
MET A 167
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
ATP  A 403 (-4.9A)
None
ATP  A 403 ( 3.7A)
ATP  A 403 ( 4.5A)
 0.77A 5yf9X-5xvuA:
45.4		 5yf9X-5xvuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YWM_X_NIOX403_0
(CASEIN KINASE II
SUBUNIT ALPHA')		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 7 VAL A  57
LYS A  72
ILE A  99
PHE A 117
ILE A 178
 ATP  A 403 (-3.9A)
ATP  A 403 (-3.2A)
ATP  A 403 (-4.9A)
None
ATP  A 403 ( 4.5A)
 0.30A 5ywmX-5xvuA:
45.1		 5ywmX-5xvuA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 12 ILE A 249
TYR A 201
LEU A 253
GLY A 228
ALA A 227
 None
 1.10A 5zwrA-5xvuA:
undetectable		 5zwrA-5xvuA:
20.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_A_ACTA401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		5 / 5 ARG A  84
ARG A 159
LEU A 182
ASN A 193
VAL A 196
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
None
 0.34A 6gmdA-5xvuA:
47.4		 6gmdA-5xvuA:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GMD_B_ACTB401_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5xvu CASEIN KINASE 2,
ALPHA SUBUNIT
(Plasmodium
falciparum) 		4 / 4 ARG A  84
ARG A 159
LEU A 182
ASN A 193
 SO4  A 401 (-2.8A)
SO4  A 401 (-3.0A)
None
SO4  A 401 (-3.7A)
 0.28A 6gmdB-5xvuA:
47.4		 6gmdB-5xvuA:
60.00