SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xwz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 7 MET A 160
PHE A 242
SER A 248
PHE A 222
 MLI  A 302 ( 4.3A)
None
None
None
 1.14A 1fxvA-5xwzA:
undetectable
1fxvB-5xwzA:
undetectable		 1fxvA-5xwzA:
undetectable
1fxvB-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 5 ILE A  16
PRO A  62
PHE A  59
ILE A  10
 None
 1.14A 2hjhA-5xwzA:
2.0		 2hjhA-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 7 GLY A  37
CYH A  39
PHE A  42
PHE A 253
 None
 1.22A 2qx4A-5xwzA:
undetectable
2qx4B-5xwzA:
undetectable		 2qx4A-5xwzA:
17.04
2qx4B-5xwzA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 6 PRO A 131
GLY A 103
GLY A 107
GLY A  35
 None
None
None
MLI  A 302 (-3.8A)
 0.46A 3bogA-5xwzA:
undetectable
3bogC-5xwzA:
undetectable		 3bogA-5xwzA:
undetectable
3bogC-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_A_DSFA319_1
(GLR4197 PROTEIN)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		5 / 9 PRO A 127
ILE A 236
ILE A 234
VAL A 213
ILE A 228
 None
 1.36A 3p4wA-5xwzA:
undetectable		 3p4wA-5xwzA:
11.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA503_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 6 SER A  67
TYR A  19
TRP A  18
PHE A  59
 None
 1.04A 4awuA-5xwzA:
undetectable		 4awuA-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		5 / 12 ALA A 108
SER A 109
VAL A 111
THR A 260
ILE A 209
 None
 1.27A 4c49A-5xwzA:
undetectable		 4c49A-5xwzA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 7 GLU A  21
THR A  58
LEU A 170
SER A  47
 None
 1.13A 4pfjA-5xwzA:
5.5		 4pfjA-5xwzA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		4 / 6 GLY A  80
THR A 110
SER A 109
GLY A 107
 None
 0.83A 5k4pA-5xwzA:
undetectable		 5k4pA-5xwzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		5 / 10 PRO A 127
ILE A 236
ILE A 234
VAL A 213
ILE A 228
 None
 1.38A 5mzrA-5xwzA:
undetectable		 5mzrA-5xwzA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		5 / 9 PRO A 127
ILE A 236
ILE A 234
VAL A 213
ILE A 228
 None
 1.37A 5mzrD-5xwzA:
undetectable		 5mzrD-5xwzA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 5xwz UNPLACED GENOMIC
SCAFFOLD
SUPERCONT1.36, WHOLE
GENOME SHOTGUN
SEQUENCE
(Cladophialophora
bantiana) 		5 / 12 ALA A 113
LEU A 204
VAL A 122
TYR A 264
ASP A 210
 None
None
NA  A 301 (-4.8A)
None
None
 0.90A 5vlmD-5xwzA:
undetectable		 5vlmD-5xwzA:
undetectable