SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xx9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 10 VAL A   7
VAL A  57
VAL A 119
ILE A 105
LEU A  11
 None
 1.27A 1fe2A-5xx9A:
undetectable		 1fe2A-5xx9A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 6 LEU A 138
PHE A  87
TYR A  43
VAL A  83
 None
 1.15A 1ibgH-5xx9A:
undetectable		 1ibgH-5xx9A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.84A 1p7lD-5xx9A:
undetectable		 1p7lD-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.86A 1p7lC-5xx9A:
undetectable		 1p7lC-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.85A 1rg9B-5xx9A:
undetectable		 1rg9B-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.84A 1rg9A-5xx9A:
undetectable		 1rg9A-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.85A 1rg9D-5xx9A:
undetectable		 1rg9D-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.86A 1rg9C-5xx9A:
undetectable		 1rg9C-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 11 GLU A  51
HIS A  54
GLU A  94
ILE A 123
GLU A 127
 FE2  A 201 (-2.0A)
FE2  A 201 (-3.4A)
FE2  A 201 ( 4.8A)
None
FE2  A 201 (-2.2A)
 0.88A 1rnrA-5xx9A:
9.8		 1rnrA-5xx9A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 12 GLU A  51
HIS A  54
GLU A  94
ILE A 123
GLU A 127
 FE2  A 201 (-2.0A)
FE2  A 201 (-3.4A)
FE2  A 201 ( 4.8A)
None
FE2  A 201 (-2.2A)
 0.87A 1rnrB-5xx9A:
9.8		 1rnrB-5xx9A:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 6 ALA A  17
GLU A  18
TYR A  25
ILE A  22
 None
FE2  A 201 (-2.0A)
None
FE2  A 203 ( 4.8A)
 0.94A 1xvaA-5xx9A:
undetectable
1xvaB-5xx9A:
undetectable		 1xvaA-5xx9A:
undetectable
1xvaB-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 12 LEU A  19
LEU A  58
ILE A   8
GLY A  67
LEU A  68
 None
 1.14A 2j7xA-5xx9A:
undetectable		 2j7xA-5xx9A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		3 / 3 TRP A  37
GLN A 158
THR A  38
 None
 1.02A 4m2xA-5xx9A:
undetectable		 4m2xA-5xx9A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.93A 4ndnB-5xx9A:
undetectable		 4ndnB-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.89A 4ndnD-5xx9A:
undetectable		 4ndnD-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 12 LEU A  19
LEU A  58
ILE A   8
GLY A  67
LEU A  68
 None
 1.11A 5gs4A-5xx9A:
undetectable		 5gs4A-5xx9A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 12 LEU A  19
LEU A  58
ILE A   8
GLY A  67
LEU A  68
 None
 1.08A 5gtrA-5xx9A:
undetectable		 5gtrA-5xx9A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		4 / 8 ALA A  97
GLU A 127
ASP A 132
ILE A 131
 None
FE2  A 201 (-2.2A)
None
None
 0.92A 5t8sA-5xx9A:
undetectable		 5t8sA-5xx9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 5xx9 BACTERIOFERRITIN
(Streptomyces
coelicolor) 		5 / 11 ASP A   4
ILE A   8
LEU A  11
ARG A  61
ILE A 114
 None
 1.31A 6fgcA-5xx9A:
undetectable		 6fgcA-5xx9A:
20.69