SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)		 5xxf PROTECTION OF
TELOMERES PROTEIN
POZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 ILE A  54
PHE A 235
TYR A 219
ILE A 106
GLU A 107
 None
 1.30A 1mrgA-5xxfA:
undetectable		 1mrgA-5xxfA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 5xxf PROTECTION OF
TELOMERES PROTEIN
POZ1
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP A  91
GLN A 159
TRP A 174
 None
 1.29A 2vqyA-5xxfA:
undetectable		 2vqyA-5xxfA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 5xxf PROTECTION OF
TELOMERES PROTEIN
POZ1
(Schizosaccharomy
ces
pombe) 		3 / 3 SER A  97
GLU A 104
ASP A 173
 None
 0.82A 2zthA-5xxfA:
undetectable		 2zthA-5xxfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5xxf PROTECTION OF
TELOMERES PROTEIN
POZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 ILE A  54
PHE A 235
TYR A 219
ILE A 106
GLU A 107
 None
 1.26A 4yp2B-5xxfA:
undetectable		 4yp2B-5xxfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 5xxf PROTECTION OF
TELOMERES PROTEIN
POZ1
(Schizosaccharomy
ces
pombe) 		5 / 9 ILE A  54
PHE A 235
TYR A 219
ILE A 106
GLU A 107
 None
 1.28A 5cf9B-5xxfA:
undetectable		 5cf9B-5xxfA:
undetectable