SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xyh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 8 TYR A 404
ILE A 405
ILE A 437
SER A 401
 None
 0.81A 1mrjA-5xyhA:
undetectable		 1mrjA-5xyhA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 8 TYR A 245
PHE A 314
ARG A 247
LEU A 232
 None
 1.10A 1x8vA-5xyhA:
undetectable		 1x8vA-5xyhA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_1
(RETINOIC ACID
RECEPTOR, BETA)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 12 LEU A 122
ILE A 173
ILE A 217
LEU A 105
LEU A  83
 None
 0.97A 1xdkB-5xyhA:
undetectable		 1xdkB-5xyhA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 8 LEU A  83
ASN A  48
HIS A 104
ALA A  88
 None
 0.95A 2bnnA-5xyhA:
undetectable
2bnnB-5xyhA:
undetectable		 2bnnA-5xyhA:
15.96
2bnnB-5xyhA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 10 GLU A 178
THR A 264
LEU A 232
LEU A 310
TYR A 306
 None
 1.34A 2ha6A-5xyhA:
undetectable		 2ha6A-5xyhA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_B_SCKB952_1
(ACETYLCHOLINESTERASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 10 GLU A 178
THR A 264
LEU A 232
LEU A 310
TYR A 306
 None
 1.34A 2ha6B-5xyhA:
undetectable		 2ha6B-5xyhA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 5 ASP A 131
SER A 137
LEU A 141
GLY A 129
 None
 1.08A 2j2pA-5xyhA:
undetectable
2j2pB-5xyhA:
undetectable		 2j2pA-5xyhA:
17.14
2j2pB-5xyhA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 12 SER A 200
ILE A 202
ALA A 197
ALA A 193
THR A 144
 None
 1.26A 2japB-5xyhA:
undetectable		 2japB-5xyhA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 12 SER A 200
ILE A 202
ALA A 197
ALA A 193
THR A 144
 None
 1.26A 2japC-5xyhA:
2.8		 2japC-5xyhA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1002_0
(ALDEHYDE
DEHYDROGENASE A)		 5xyh CBSA
(Xanthomonas
oryzae) 		3 / 3 GLY A 394
ARG A 331
TYR A  51
 None
 0.87A 2opxA-5xyhA:
undetectable		 2opxA-5xyhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		3 / 3 GLY A 345
TYR A 351
SER A 344
 None
 0.74A 2xatA-5xyhA:
undetectable		 2xatA-5xyhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 11 ILE A 457
ILE A 374
GLY A 375
PHE A 446
GLY A 394
 None
 1.00A 4ac9B-5xyhA:
3.0
4ac9C-5xyhA:
2.5		 4ac9B-5xyhA:
undetectable
4ac9C-5xyhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 7 TYR A 351
SER A 299
LEU A 277
PHE A 301
 None
 1.03A 4uymA-5xyhA:
undetectable		 4uymA-5xyhA:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 6 ARG A 339
ASP A 358
ARG A 360
GLY A 371
 None
 1.01A 5cdqA-5xyhA:
undetectable
5cdqC-5xyhA:
undetectable
5cdqD-5xyhA:
undetectable		 5cdqA-5xyhA:
11.49
5cdqC-5xyhA:
11.49
5cdqD-5xyhA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5xyh CBSA
(Xanthomonas
oryzae) 		4 / 5 LEU A 109
TYR A  46
LEU A 171
TYR A 168
 None
 1.45A 5ki6A-5xyhA:
undetectable		 5ki6A-5xyhA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5xyh CBSA
(Xanthomonas
oryzae) 		5 / 12 ASP A 131
LEU A 244
ALA A 197
PRO A 128
ARG A 130
 None
 1.12A 5syfB-5xyhA:
3.2		 5syfB-5xyhA:
10.93