SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xyi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 LEU C 149
TYR C 146
THR A 107
TYR A 109
None
None
G  21102 ( 3.2A)
U  21101 ( 3.9A)
1.32A 1afsA-5xyiC:
undetectable
1afsA-5xyiC:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 LEU C 149
TYR C 146
THR A 107
TYR A 109
None
None
G  21102 ( 3.2A)
U  21101 ( 3.9A)
1.32A 1afsB-5xyiC:
undetectable
1afsB-5xyiC:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 7 ASN E 127
THR E 146
GLY E 144
ASP E 143
None
G  2 112 ( 3.6A)
U  2 228 ( 4.7A)
None
0.99A 1bu5A-5xyiE:
undetectable
1bu5A-5xyiE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 8 ASN E 127
THR E 146
GLY E 144
ASP E 143
None
G  2 112 ( 3.6A)
U  2 228 ( 4.7A)
None
0.96A 1bu5B-5xyiE:
undetectable
1bu5B-5xyiE:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 11 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.89A 1c6yA-5xyiX:
undetectable
1c6yA-5xyiX:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 12 LEU V  78
ILE V  71
ALA V  72
VAL V  52
LEU A 183
None
1.05A 1cbsA-5xyiV:
undetectable
1cbsA-5xyiV:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_A_H4BA700_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 1d1vA-5xyic:
undetectable
1d1vB-5xyic:
undetectable
1d1vA-5xyic:
12.80
1d1vB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1V_B_H4BB701_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 1d1vA-5xyiF:
undetectable
1d1vB-5xyiF:
undetectable
1d1vA-5xyiF:
18.04
1d1vB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 1d1wA-5xyic:
undetectable
1d1wB-5xyic:
undetectable
1d1wA-5xyic:
12.80
1d1wB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1W_B_H4BB601_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 1d1wA-5xyiF:
undetectable
1d1wB-5xyiF:
undetectable
1d1wA-5xyiF:
18.04
1d1wB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_A_H4BA600_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 1d1xA-5xyic:
undetectable
1d1xB-5xyic:
undetectable
1d1xA-5xyic:
12.80
1d1xB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1X_B_H4BB601_1
(BOVINE ENDOTHELIAL
NITRIC OXIDE
SYNTHASE HEME DOMAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 1d1xA-5xyiF:
undetectable
1d1xB-5xyiF:
undetectable
1d1xA-5xyiF:
18.04
1d1xB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_A_H4BA1600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 1dm8A-5xyic:
undetectable
1dm8B-5xyic:
undetectable
1dm8A-5xyic:
12.80
1dm8B-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DM8_B_H4BB2600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.92A 1dm8A-5xyiF:
undetectable
1dm8B-5xyiF:
undetectable
1dm8A-5xyiF:
18.04
1dm8B-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 8 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.96A 1dmiA-5xyic:
undetectable
1dmiB-5xyic:
undetectable
1dmiA-5xyic:
12.80
1dmiB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_B_BHSB2610_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 1dmiA-5xyiF:
undetectable
1dmiB-5xyiF:
undetectable
1dmiA-5xyiF:
18.04
1dmiB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.96A 1fbyA-5xyiT:
undetectable
1fbyA-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.97A 1fbyB-5xyiT:
undetectable
1fbyB-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ASN A  95
SER C 259
GLY A  93
PHE A  88
VAL A  85
None
1.07A 1ffyA-5xyiA:
undetectable
1ffyA-5xyiA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.92A 1fm6A-5xyiT:
undetectable
1fm6A-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
LEU T 111
None
0.99A 1fm6A-5xyiT:
undetectable
1fm6A-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.96A 1fm9A-5xyiT:
undetectable
1fm9A-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.29A 1fohA-5xyiC:
undetectable
1fohA-5xyiC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.29A 1fohB-5xyiC:
undetectable
1fohB-5xyiC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.27A 1fohC-5xyiC:
undetectable
1fohC-5xyiC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_D_IPHD802_0
(PHENOL HYDROXYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.30A 1fohD-5xyiC:
undetectable
1fohD-5xyiC:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_B_H4BB2600_1
(NITRIC-OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.91A 1fopA-5xyiF:
undetectable
1fopB-5xyiF:
undetectable
1fopA-5xyiF:
18.04
1fopB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)
5xyi 40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
4 / 6 PHE A 101
GLU A 134
VAL A  72
MET A 120
None
A  21131 ( 3.1A)
None
None
1.06A 1hk1A-5xyiA:
undetectable
1hk1A-5xyiA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE C 225
ILE C 116
LYS C 201
ALA C 199
None
1.19A 1hk2A-5xyiC:
undetectable
1hk2A-5xyiC:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.92A 1hxbB-5xyiX:
undetectable
1hxbB-5xyiX:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
5 / 10 LEU F  61
LEU F 140
ILE F  28
PHE F   7
ILE F  98
None
1.35A 1i18A-5xyiF:
undetectable
1i18B-5xyiF:
undetectable
1i18A-5xyiF:
20.20
1i18B-5xyiF:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
5 / 10 PHE F   7
ILE F  98
LEU F  61
LEU F 140
ILE F  28
None
1.39A 1i18A-5xyiF:
undetectable
1i18B-5xyiF:
undetectable
1i18A-5xyiF:
20.20
1i18B-5xyiF:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.94A 1k74A-5xyiT:
undetectable
1k74A-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 1nseA-5xyic:
undetectable
1nseB-5xyic:
undetectable
1nseA-5xyic:
12.80
1nseB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NSE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 1nseA-5xyiF:
undetectable
1nseB-5xyiF:
undetectable
1nseA-5xyiF:
18.04
1nseB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 1p6lA-5xyic:
undetectable
1p6lB-5xyic:
undetectable
1p6lA-5xyic:
10.71
1p6lB-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6L_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 1p6lA-5xyiF:
undetectable
1p6lB-5xyiF:
undetectable
1p6lA-5xyiF:
18.78
1p6lB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 1p6mA-5xyiF:
undetectable
1p6mB-5xyiF:
undetectable
1p6mA-5xyiF:
18.78
1p6mB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6N_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 1p6nA-5xyiF:
undetectable
1p6nB-5xyiF:
undetectable
1p6nA-5xyiF:
18.78
1p6nB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)
5xyi RIBOSOMAL PROTEIN
S3, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU D  67
GLY D  36
GLY D  34
ILE D  89
LEU D  85
None
0.94A 1p91B-5xyiD:
undetectable
1p91B-5xyiD:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)
5xyi 40S RIBOSOMAL
PROTEIN S29,
PUTATIVE
RIBOSOMAL PROTEIN
S10P/S20E, PUTATIVE
RIBOSOMAL PROTEIN
S3, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU d  51
GLY D  16
ARG d  23
THR U  29
ILE U  88
None
1.45A 1p93A-5xyid:
undetectable
1p93A-5xyid:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)
5xyi 40S RIBOSOMAL
PROTEIN S29,
PUTATIVE

(Trichomonas
vaginalis)
3 / 3 CYH d  43
ARG d  47
CYH d  22
G  21242 ( 3.9A)
G  21242 ( 4.7A)
None
1.32A 1p9gA-5xyid:
undetectable
1p9gA-5xyid:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.27A 1pn0A-5xyiC:
undetectable
1pn0A-5xyiC:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.27A 1pn0B-5xyiC:
undetectable
1pn0B-5xyiC:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.31A 1pn0C-5xyiC:
undetectable
1pn0C-5xyiC:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 10 GLY C 124
MET C 233
VAL C 154
ILE C 126
GLY C 122
None
1.30A 1pn0D-5xyiC:
undetectable
1pn0D-5xyiC:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 1q2oA-5xyic:
undetectable
1q2oB-5xyic:
undetectable
1q2oA-5xyic:
10.71
1q2oB-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q2O_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 1q2oA-5xyiF:
undetectable
1q2oB-5xyiF:
undetectable
1q2oA-5xyiF:
18.78
1q2oB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))
5xyi RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 VAL Y  54
ILE Y  56
ILE Y  24
ILE Y   8
PHE Y  22
None
None
None
A  2 628 ( 4.5A)
None
0.98A 1qhsA-5xyiY:
undetectable
1qhsA-5xyiY:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ARG g  75
VAL g  49
TRP g  60
None
1.26A 1qw6A-5xyig:
undetectable
1qw6A-5xyig:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ARG g  75
VAL g  49
TRP g  60
None
1.20A 1qwcA-5xyig:
undetectable
1qwcA-5xyig:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 12 ALA O  69
ALA O  81
ALA O  85
VAL O  52
LEU O 127
None
1.09A 1rbpA-5xyiO:
undetectable
1rbpA-5xyiO:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 1rs8A-5xyic:
undetectable
1rs8B-5xyic:
undetectable
1rs8A-5xyic:
10.71
1rs8B-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS8_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 1rs8A-5xyiF:
undetectable
1rs8B-5xyiF:
undetectable
1rs8A-5xyiF:
18.78
1rs8B-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 1rs9A-5xyic:
undetectable
1rs9B-5xyic:
undetectable
1rs9A-5xyic:
10.71
1rs9B-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS9_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.04A 1rs9A-5xyiF:
undetectable
1rs9B-5xyiF:
undetectable
1rs9A-5xyiF:
18.78
1rs9B-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE
40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 8 LEU Q  41
TYR Q  76
GLY Q  70
LEU F  76
None
None
U  21414 ( 3.2A)
C  21334 ( 3.7A)
1.00A 1s1xA-5xyiQ:
undetectable
1s1xA-5xyiQ:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)
5xyi RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis)
4 / 5 LEU W  93
ALA W  91
LEU W  94
SER W  96
None
1.02A 1tt6B-5xyiW:
undetectable
1tt6B-5xyiW:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)
5xyi 40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
4 / 7 LYS A  14
LEU A 175
ALA A  18
SER A 168
None
0.90A 1tyrB-5xyiA:
undetectable
1tyrB-5xyiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)
5xyi 40S RIBOSOMAL
PROTEIN S8

(Trichomonas
vaginalis)
4 / 5 GLU I  40
THR I  36
LEU I  58
LEU I  60
None
None
C  21483 ( 4.3A)
None
1.10A 1u18B-5xyiI:
undetectable
1u18B-5xyiI:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ARG g  75
VAL g  49
TRP g  60
None
1.21A 1vagA-5xyig:
undetectable
1vagA-5xyig:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
LEU T  25
ALA T  26
LEU T 111
None
0.98A 1xdkA-5xyiT:
undetectable
1xdkA-5xyiT:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.97A 1xdkE-5xyiT:
undetectable
1xdkE-5xyiT:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
LEU T  25
ALA T  26
LEU T 111
None
0.98A 1xdkE-5xyiT:
undetectable
1xdkE-5xyiT:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.96A 1xiuA-5xyiT:
undetectable
1xiuA-5xyiT:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
LEU T  25
ALA T  26
LEU T 111
None
0.99A 1xiuA-5xyiT:
undetectable
1xiuA-5xyiT:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
4 / 5 ALA V  30
TYR A 137
ALA V  60
GLN A 130
None
G  21104 ( 4.6A)
G  2 891 ( 3.6A)
A  21131 ( 3.6A)
1.00A 1xl6A-5xyiV:
undetectable
1xl6B-5xyiV:
undetectable
1xl6A-5xyiV:
13.95
1xl6B-5xyiV:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
3 / 3 TRP J  41
ARG J  38
PHE J  10
None
C  2 404 ( 4.2A)
None
1.35A 1zeaH-5xyiJ:
undetectable
1zeaL-5xyiJ:
undetectable
1zeaH-5xyiJ:
21.21
1zeaL-5xyiJ:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN S13,
PUTATIVE

(Trichomonas
vaginalis)
4 / 5 TRP N  25
PRO N  23
GLY N  59
GLY N  61
None
None
None
U  2 779 ( 3.1A)
0.99A 1zlqA-5xyiN:
undetectable
1zlqA-5xyiN:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ARG g  75
VAL g  49
TRP g  60
None
1.20A 1zviA-5xyig:
undetectable
1zviA-5xyig:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.05A 1zzrA-5xyic:
undetectable
1zzrB-5xyic:
undetectable
1zzrA-5xyic:
11.41
1zzrB-5xyic:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 1zzsA-5xyiF:
undetectable
1zzsB-5xyiF:
undetectable
1zzsA-5xyiF:
18.78
1zzsB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.05A 1zzuA-5xyic:
undetectable
1zzuB-5xyic:
undetectable
1zzuA-5xyic:
11.41
1zzuB-5xyic:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.03A 1zzuA-5xyiF:
undetectable
1zzuB-5xyiF:
undetectable
1zzuA-5xyiF:
17.42
1zzuB-5xyiF:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 11 ALA O  86
ALA O  85
GLN O  87
LEU O  84
ALA O 126
None
0.99A 2aclE-5xyiO:
undetectable
2aclE-5xyiO:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 12 ALA O  86
ALA O  85
GLN O  87
LEU O  84
ALA O 126
None
0.95A 2aclG-5xyiO:
undetectable
2aclG-5xyiO:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.94A 2aclG-5xyiT:
undetectable
2aclG-5xyiT:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
4 / 5 LEU V  68
ASP A 156
GLY V  56
ALA V  67
None
0.70A 2aohA-5xyiV:
undetectable
2aohA-5xyiV:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
5 / 11 ARG E 100
ILE E 101
GLY E  91
PHE E  47
TYR E  82
None
1.19A 2azyA-5xyiE:
undetectable
2azyA-5xyiE:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 GLY F 146
ARG F 180
ASP F 164
CYH F 161
ALA F 150
None
1.03A 2bm9A-5xyiF:
undetectable
2bm9A-5xyiF:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE
GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 LYS g 230
ASP R  30
ASP g 124
None
1.05A 2br4A-5xyig:
undetectable
2br4A-5xyig:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)
5xyi RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 ASN Y  14
GLN Y  21
THR Y  84
PRO Y  86
None
1.36A 2ez7A-5xyiY:
undetectable
2ez7A-5xyiY:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 12 LEU V  78
ILE V  71
ALA V  72
VAL V  52
LEU A 183
None
1.10A 2fr3A-5xyiV:
undetectable
2fr3A-5xyiV:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G78_A_REAA200_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 12 LEU V  78
ILE V  71
ALA V  72
VAL V  52
LEU A 183
None
1.07A 2g78A-5xyiV:
undetectable
2g78A-5xyiV:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 2hx2A-5xyic:
undetectable
2hx2B-5xyic:
undetectable
2hx2A-5xyic:
10.71
2hx2B-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX2_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 2hx2A-5xyiF:
undetectable
2hx2B-5xyiF:
undetectable
2hx2A-5xyiF:
18.78
2hx2B-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ALA C 147
ALA C  80
ALA C 117
GLY C 120
GLY C 127
None
0.98A 2igtA-5xyiC:
undetectable
2igtA-5xyiC:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ALA C 147
ALA C  80
ALA C 117
GLY C 120
GLY C 127
None
0.97A 2igtB-5xyiC:
undetectable
2igtB-5xyiC:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 11 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.90A 2nnpB-5xyiX:
undetectable
2nnpB-5xyiX:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 2nseA-5xyic:
undetectable
2nseB-5xyic:
undetectable
2nseA-5xyic:
12.80
2nseB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)
5xyi 40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
3 / 3 LEU A 145
MET A 169
MET A  15
None
1.05A 2vavF-5xyiA:
undetectable
2vavF-5xyiA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_A_IBPA1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
4 / 7 ILE Q  26
LEU Q  25
GLY Q  22
GLY Q  58
None
0.61A 2wd9A-5xyiQ:
undetectable
2wd9A-5xyiQ:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
4 / 8 ILE Q  26
LEU Q  25
GLY Q  22
GLY Q  58
None
0.60A 2wd9B-5xyiQ:
undetectable
2wd9B-5xyiQ:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 11 THR C 219
SER C 215
GLY C 196
ALA C 198
ARG J  15
U  2   3 ( 4.1A)
U  2   3 ( 3.5A)
U  2   3 ( 3.9A)
U  2   4 ( 4.3A)
U  2   3 ( 2.9A)
1.33A 2xh9A-5xyiC:
undetectable
2xh9A-5xyiC:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE
GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
5 / 12 GLN R  23
GLY g 189
GLY g 211
ASP g 210
ASN g 144
None
1.08A 2zw9B-5xyiR:
undetectable
2zw9B-5xyiR:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
4 / 7 ALA Q  15
ALA Q  13
VAL Q  64
ILE Q  45
None
0.79A 3a2qA-5xyiQ:
undetectable
3a2qA-5xyiQ:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)
5xyi RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis)
5 / 12 VAL W  73
GLY W 127
ILE W 125
LYS W 124
PRO W  77
None
None
None
U  2 650 ( 3.3A)
G  2 911 ( 4.9A)
1.09A 3bjwF-5xyiW:
undetectable
3bjwF-5xyiW:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
3 / 3 PRO Q 123
PHE Q 126
LYS Q 124
C  21412 ( 4.3A)
None
A  21411 ( 2.8A)
1.23A 3bjwG-5xyiQ:
undetectable
3bjwG-5xyiQ:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
4 / 4 VAL O  50
ARG O 125
ILE O 137
THR O  48
None
0.89A 3cl9A-5xyiO:
undetectable
3cl9A-5xyiO:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 PHE B  96
CYH B 181
PHE B 184
None
1.10A 3cr5X-5xyiB:
undetectable
3cr5X-5xyiB:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
3 / 3 ARG E 245
VAL E 225
THR E 220
U  2 635 ( 4.7A)
None
A  2 601 ( 4.5A)
0.67A 3cyxA-5xyiE:
undetectable
3cyxA-5xyiE:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)
5xyi 40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 12 LEU A  92
ASP A  71
LEU A  73
LEU A 145
ALA A  59
None
1.08A 3dfrA-5xyiA:
undetectable
3dfrA-5xyiA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
RIBOSOMAL PROTEIN
S14
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 8 ARG O 129
GLN c   7
GLU F 186
GLU c  59
None
1.37A 3dh0A-5xyiO:
undetectable
3dh0A-5xyiO:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.09A 3dqrA-5xyic:
undetectable
3dqrB-5xyic:
undetectable
3dqrA-5xyic:
11.36
3dqrB-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 3dqsA-5xyic:
undetectable
3dqsB-5xyic:
undetectable
3dqsA-5xyic:
10.71
3dqsB-5xyic:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 3dqsA-5xyiF:
undetectable
3dqsB-5xyiF:
undetectable
3dqsA-5xyiF:
18.78
3dqsB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 3dqtA-5xyiF:
undetectable
3dqtB-5xyiF:
undetectable
3dqtA-5xyiF:
18.78
3dqtB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 10 LEU V  68
ASP A 156
ASP A 153
GLY V  56
ALA V  67
None
None
U  2 889 ( 2.7A)
None
None
0.92A 3ekpB-5xyiV:
undetectable
3ekpB-5xyiV:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S21
40S RIBOSOMAL
PROTEIN SA

(Trichomonas
vaginalis)
5 / 10 LEU V  68
ASP A 156
ASP A 153
GLY V  56
ALA V  67
None
None
U  2 889 ( 2.7A)
None
None
0.91A 3ekpC-5xyiV:
undetectable
3ekpC-5xyiV:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 10 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.95A 3el5A-5xyiX:
undetectable
3el5A-5xyiX:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5xyi RIBOSOMAL PROTEIN
S13P/S18E, PUTATIVE

(Trichomonas
vaginalis)
5 / 8 ILE S  35
PRO S  76
ASN S  75
HIS S  79
VAL S  46
None
0.94A 3em0B-5xyiS:
undetectable
3em0B-5xyiS:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 ASP g  42
ALA g  92
ASP g  91
LEU g  96
VAL g  59
None
1.20A 3em4B-5xyig:
undetectable
3em4B-5xyig:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_A_ADNA300_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ALA C 206
GLY C 127
VAL C 119
GLY C 120
VAL C 154
None
1.00A 3f8wA-5xyiC:
undetectable
3f8wA-5xyiC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ALA C 206
GLY C 127
VAL C 119
GLY C 120
VAL C 154
None
1.02A 3f8wC-5xyiC:
undetectable
3f8wC-5xyiC:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 10 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.89A 3falC-5xyiT:
undetectable
3falC-5xyiT:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 11 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.87A 3fc6A-5xyiT:
undetectable
3fc6A-5xyiT:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 10 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fhjA-5xyig:
undetectable
3fhjA-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 10 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.34A 3fhjB-5xyig:
undetectable
3fhjB-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 10 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fhjC-5xyig:
undetectable
3fhjC-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fhjD-5xyig:
undetectable
3fhjD-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 10 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fhjE-5xyig:
undetectable
3fhjE-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fhjF-5xyig:
undetectable
3fhjF-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.37A 3fi0A-5xyig:
undetectable
3fi0A-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.37A 3fi0C-5xyig:
undetectable
3fi0C-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.35A 3fi0D-5xyig:
undetectable
3fi0D-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.37A 3fi0F-5xyig:
undetectable
3fi0F-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.39A 3fi0J-5xyig:
undetectable
3fi0J-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.39A 3fi0L-5xyig:
undetectable
3fi0L-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.37A 3fi0M-5xyig:
undetectable
3fi0M-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 GLY g 127
VAL g 125
HIS g 121
ILE g 138
VAL g 184
None
1.37A 3fi0R-5xyig:
undetectable
3fi0R-5xyig:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN S7, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE H  24
VAL H   5
ILE H  69
GLU H  62
VAL H  42
None
1.16A 3fpjB-5xyiH:
undetectable
3fpjB-5xyiH:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 7 VAL F  53
ILE F 136
TYR F  27
ILE F  28
None
1.05A 3hgxA-5xyiF:
undetectable
3hgxA-5xyiF:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_B_SALB104_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
5 / 9 VAL F  53
VAL F 105
ILE F 136
TYR F  27
ILE F  28
None
1.38A 3hgxB-5xyiF:
undetectable
3hgxB-5xyiF:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 8 TYR F  10
PHE F   7
VAL F  38
ILE Z  77
None
0.74A 3hjoA-5xyiF:
undetectable
3hjoA-5xyiF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)
5xyi RIBOSOMAL PROTEIN
S3, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ILE D 183
SER D 151
SER D 149
None
0.59A 3iltH-5xyiD:
undetectable
3iltH-5xyiD:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 3jwxA-5xyiF:
undetectable
3jwxB-5xyiF:
undetectable
3jwxA-5xyiF:
18.04
3jwxB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 3jwyA-5xyic:
undetectable
3jwyB-5xyic:
undetectable
3jwyA-5xyic:
12.80
3jwyB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.01A 3jwyA-5xyiF:
undetectable
3jwyB-5xyiF:
undetectable
3jwyA-5xyiF:
18.04
3jwyB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 3jwzA-5xyic:
undetectable
3jwzB-5xyic:
undetectable
3jwzA-5xyic:
12.80
3jwzB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 3jwzA-5xyiF:
undetectable
3jwzB-5xyiF:
undetectable
3jwzA-5xyiF:
18.04
3jwzB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.05A 3jx2A-5xyic:
undetectable
3jx2B-5xyic:
undetectable
3jx2A-5xyic:
11.36
3jx2B-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.06A 3jx3A-5xyic:
undetectable
3jx3B-5xyic:
undetectable
3jx3A-5xyic:
11.36
3jx3B-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.10A 3jx6A-5xyic:
undetectable
3jx6B-5xyic:
undetectable
3jx6A-5xyic:
11.36
3jx6B-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.92A 3k4vC-5xyiX:
undetectable
3k4vC-5xyiX:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ALA X  12
ARG X  16
LYS X  20
None
None
C  2 242 ( 4.4A)
0.66A 3kp3B-5xyiX:
undetectable
3kp3B-5xyiX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ALA X  12
ARG X  16
LYS X  20
None
None
C  2 242 ( 4.4A)
0.87A 3kp5B-5xyiX:
undetectable
3kp5B-5xyiX:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 8 GLU B  24
LYS B  23
ASN B  46
ILE B  21
None
C  2 716 ( 2.7A)
None
None
1.13A 3kp6A-5xyiB:
undetectable
3kp6B-5xyiB:
undetectable
3kp6A-5xyiB:
20.49
3kp6B-5xyiB:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 7 ASN B 175
LEU B 180
ASP B 183
LYS B 182
None
1.34A 3lslA-5xyiB:
undetectable
3lslD-5xyiB:
undetectable
3lslA-5xyiB:
25.00
3lslD-5xyiB:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 ASN B 175
LEU B 180
ASP B 183
LYS B 182
None
1.38A 3lslG-5xyiB:
undetectable
3lslG-5xyiB:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 3n5rA-5xyic:
undetectable
3n5rB-5xyic:
undetectable
3n5rA-5xyic:
12.80
3n5rB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 3n5rA-5xyiF:
undetectable
3n5rB-5xyiF:
undetectable
3n5rA-5xyiF:
18.04
3n5rB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 3n5sA-5xyiF:
undetectable
3n5sB-5xyiF:
undetectable
3n5sA-5xyiF:
18.04
3n5sB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 3n5tA-5xyic:
undetectable
3n5tB-5xyic:
undetectable
3n5tA-5xyic:
12.80
3n5tB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 3n5tA-5xyiF:
undetectable
3n5tB-5xyiF:
undetectable
3n5tA-5xyiF:
18.04
3n5tB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 3n6eA-5xyiF:
undetectable
3n6eB-5xyiF:
undetectable
3n6eA-5xyiF:
18.04
3n6eB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_A_URFA521_1
(RNA DEPENDENT RNA
POLYMERASE)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 5 ASP E 143
ASP E  73
ASP E  88
ARG E 100
None
1.12A 3naiA-5xyiE:
undetectable
3naiA-5xyiE:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 3nlgA-5xyic:
undetectable
3nlgB-5xyic:
undetectable
3nlgA-5xyic:
12.80
3nlgB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 3nlgA-5xyiF:
undetectable
3nlgB-5xyiF:
undetectable
3nlgA-5xyiF:
18.04
3nlgB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.09A 3nljA-5xyic:
undetectable
3nljB-5xyic:
undetectable
3nljA-5xyic:
11.36
3nljB-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.10A 3nlrA-5xyic:
undetectable
3nlrB-5xyic:
undetectable
3nlrA-5xyic:
11.36
3nlrB-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 TYR Q  76
GLY Q   8
ALA Q  15
ASP Q 117
ALA Q 116
None
1.15A 3nmuA-5xyiQ:
undetectable
3nmuF-5xyiQ:
undetectable
3nmuA-5xyiQ:
16.36
3nmuF-5xyiQ:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NOS_A_H4BA511_1
(ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.06A 3nosA-5xyic:
undetectable
3nosB-5xyic:
undetectable
3nosA-5xyic:
10.28
3nosB-5xyic:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 9 ALA L 124
ILE L  36
ILE L 109
VAL L  62
ILE L  64
None
None
None
None
G  2 188 ( 4.9A)
1.08A 3nu4A-5xyiL:
undetectable
3nu4A-5xyiL:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 TYR Q  76
GLY Q   8
ALA Q  15
ASP Q 117
ALA Q 116
None
1.20A 3nvkF-5xyiQ:
undetectable
3nvkJ-5xyiQ:
undetectable
3nvkF-5xyiQ:
16.49
3nvkJ-5xyiQ:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.01A 3pnhA-5xyiF:
undetectable
3pnhB-5xyiF:
1.7
3pnhA-5xyiF:
18.78
3pnhB-5xyiF:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 8 VAL F  53
VAL F 105
TYR F  27
ILE F  28
None
1.05A 3remB-5xyiF:
undetectable
3remB-5xyiF:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE
40S RIBOSOMAL
PROTEIN S26

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 7 LEU B  74
ASP B  73
ALA B  68
TYR a  59
None
1.09A 3rodD-5xyiB:
undetectable
3rodD-5xyiB:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 3rqoA-5xyic:
undetectable
3rqoB-5xyic:
undetectable
3rqoA-5xyic:
12.84
3rqoB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.02A 3rqoA-5xyiF:
undetectable
3rqoB-5xyiF:
undetectable
3rqoA-5xyiF:
18.08
3rqoB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 GLY C 175
ALA C 232
VAL C 154
PRO C 186
ILE C 185
None
None
None
None
A  2   1 ( 4.5A)
0.82A 3s56A-5xyiC:
undetectable
3s56A-5xyiC:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.91A 3spkB-5xyiX:
undetectable
3spkB-5xyiX:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 11 THR C 172
VAL C 169
SER C 215
LEU C 203
VAL C 194
U  2 907 ( 3.7A)
None
U  2   3 ( 3.5A)
None
C  2   2 ( 4.7A)
1.34A 3tbgA-5xyiC:
undetectable
3tbgA-5xyiC:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
3 / 3 LYS O 104
VAL O  38
HIS O 102
None
1.09A 3tj7A-5xyiO:
undetectable
3tj7A-5xyiO:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_C_ACTC207_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)
5xyi 40S RIBOSOMAL
PROTEIN S26

(Trichomonas
vaginalis)
4 / 4 LYS a  66
PRO a  65
LEU a  64
ASN a  43
None
1.49A 3tpxC-5xyia:
undetectable
3tpxC-5xyia:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 7 ASN F 157
ALA F 159
ARG F 148
ALA F 151
U  21283 ( 3.6A)
None
U  21283 ( 4.9A)
U  21283 ( 4.2A)
1.10A 3twpA-5xyiF:
undetectable
3twpA-5xyiF:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TX2_A_BEZA251_0
(PROBABLE
6-PHOSPHOGLUCONOLACT
ONASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 7 ARG R  81
ALA A 212
TRP R  84
ALA A 209
None
1.19A 3tx2A-5xyiR:
undetectable
3tx2A-5xyiR:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)
5xyi RIBOSOMAL PROTEIN
S15A
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 8 THR J  59
ARG J  67
PRO J  61
GLY W  84
None
0.89A 3tzfB-5xyiJ:
undetectable
3tzfB-5xyiJ:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 7 LEU V  77
LEU V  78
ILE V  71
MET V  18
None
0.99A 3u5jA-5xyiV:
undetectable
3u5jA-5xyiV:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
5 / 10 GLU E  97
SER E  95
ILE E  64
ALA E  55
GLU E  60
None
1.40A 3u6tA-5xyiE:
undetectable
3u6tA-5xyiE:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 ALA C 198
LEU C 202
MET C 205
ALA C 118
ILE C 116
U  2   4 ( 4.3A)
None
None
None
None
1.13A 3ut5B-5xyiC:
undetectable
3ut5B-5xyiC:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5xyi RIBOSOMAL PROTEIN
S3, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 LYS D 201
ARG D  94
LEU D 191
None
1.29A 3v4tE-5xyiD:
undetectable
3v4tE-5xyiD:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 5 ASP E 143
GLU E  40
GLY E  85
ASP E  73
None
1.34A 3w9tD-5xyiE:
undetectable
3w9tD-5xyiE:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5xyi RIBOSOMAL PROTEIN
S3, PUTATIVE
PLECTIN/S10 DOMAIN
CONTAINING PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 8 TYR K  42
TYR K  65
ARG D  28
LEU D  25
None
None
A  21245 ( 3.9A)
None
1.08A 3wipG-5xyiK:
undetectable
3wipH-5xyiK:
undetectable
3wipG-5xyiK:
21.98
3wipH-5xyiK:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
5xyi RIBOSOMAL PROTEIN
S3, PUTATIVE
PLECTIN/S10 DOMAIN
CONTAINING PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 8 ARG D  28
LEU D  25
TYR K  42
TYR K  65
A  21245 ( 3.9A)
None
None
None
1.09A 3wipF-5xyiD:
undetectable
3wipJ-5xyiD:
undetectable
3wipF-5xyiD:
20.66
3wipJ-5xyiD:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 HIS g 255
SER g 215
GLU g  37
ASP g 124
None
1.29A 4blvA-5xyig:
undetectable
4blvA-5xyig:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 4c3aA-5xyic:
undetectable
4c3aB-5xyic:
undetectable
4c3aA-5xyic:
12.84
4c3aB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4c3aA-5xyiF:
undetectable
4c3aB-5xyiF:
undetectable
4c3aA-5xyiF:
18.08
4c3aB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 4carA-5xyic:
undetectable
4carB-5xyic:
undetectable
4carA-5xyic:
12.84
4carB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.01A 4carA-5xyiF:
undetectable
4carB-5xyiF:
undetectable
4carA-5xyiF:
18.08
4carB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 4cftA-5xyic:
undetectable
4cftB-5xyic:
undetectable
4cftA-5xyic:
12.84
4cftB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CFT_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4cftA-5xyiF:
undetectable
4cftB-5xyiF:
0.9
4cftA-5xyiF:
18.08
4cftB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 4ctyA-5xyic:
undetectable
4ctyB-5xyic:
undetectable
4ctyA-5xyic:
12.84
4ctyB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 4cu0A-5xyic:
undetectable
4cu0B-5xyic:
undetectable
4cu0A-5xyic:
12.84
4cu0B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4cu0A-5xyiF:
undetectable
4cu0B-5xyiF:
undetectable
4cu0A-5xyiF:
18.08
4cu0B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 4cu1A-5xyic:
undetectable
4cu1B-5xyic:
undetectable
4cu1A-5xyic:
12.84
4cu1B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU1_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4cu1A-5xyiF:
undetectable
4cu1B-5xyiF:
undetectable
4cu1A-5xyiF:
18.08
4cu1B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 4cwvA-5xyic:
undetectable
4cwvB-5xyic:
undetectable
4cwvA-5xyic:
12.84
4cwvB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWV_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 4cwvA-5xyiF:
undetectable
4cwvB-5xyiF:
undetectable
4cwvA-5xyiF:
18.08
4cwvB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 4cwwA-5xyic:
undetectable
4cwwB-5xyic:
undetectable
4cwwA-5xyic:
12.84
4cwwB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 4cwwA-5xyiF:
undetectable
4cwwB-5xyiF:
undetectable
4cwwA-5xyiF:
18.08
4cwwB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4cwxA-5xyiF:
undetectable
4cwxB-5xyiF:
undetectable
4cwxA-5xyiF:
18.08
4cwxB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4cwyA-5xyiF:
undetectable
4cwyB-5xyiF:
undetectable
4cwyA-5xyiF:
18.08
4cwyB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 4cwzA-5xyic:
undetectable
4cwzB-5xyic:
undetectable
4cwzA-5xyic:
12.84
4cwzB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 4cx0A-5xyic:
undetectable
4cx0B-5xyic:
undetectable
4cx0A-5xyic:
12.84
4cx0B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.01A 4cx0A-5xyiF:
undetectable
4cx0B-5xyiF:
undetectable
4cx0A-5xyiF:
18.08
4cx0B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 4cx3A-5xyic:
undetectable
4cx3B-5xyic:
undetectable
4cx3A-5xyic:
11.36
4cx3B-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.05A 4cx4A-5xyic:
undetectable
4cx4B-5xyic:
undetectable
4cx4A-5xyic:
11.36
4cx4B-5xyic:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_A_H4BA1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 4d1oA-5xyic:
undetectable
4d1oB-5xyic:
undetectable
4d1oA-5xyic:
10.11
4d1oB-5xyic:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1O_B_H4BB1481_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 4d1oA-5xyiF:
undetectable
4d1oB-5xyiF:
undetectable
4d1oA-5xyiF:
18.69
4d1oB-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 4d1pA-5xyiF:
undetectable
4d1pB-5xyiF:
undetectable
4d1pA-5xyiF:
18.69
4d1pB-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.95A 4d34A-5xyic:
undetectable
4d34B-5xyic:
undetectable
4d34A-5xyic:
12.84
4d34B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D34_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 4d34A-5xyiF:
undetectable
4d34B-5xyiF:
undetectable
4d34A-5xyiF:
18.08
4d34B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D35_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4d35A-5xyiF:
undetectable
4d35B-5xyiF:
undetectable
4d35A-5xyiF:
18.08
4d35B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4d36A-5xyiF:
undetectable
4d36B-5xyiF:
undetectable
4d36A-5xyiF:
18.08
4d36B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4d37A-5xyiF:
undetectable
4d37B-5xyiF:
undetectable
4d37A-5xyiF:
18.08
4d37B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 4d38A-5xyic:
undetectable
4d38B-5xyic:
undetectable
4d38A-5xyic:
12.84
4d38B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D38_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4d38A-5xyiF:
undetectable
4d38B-5xyiF:
undetectable
4d38A-5xyiF:
18.08
4d38B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 4d39A-5xyiF:
undetectable
4d39B-5xyiF:
undetectable
4d39A-5xyiF:
18.08
4d39B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 4d3aA-5xyic:
undetectable
4d3aB-5xyic:
undetectable
4d3aA-5xyic:
12.84
4d3aB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 4d3aA-5xyiF:
undetectable
4d3aB-5xyiF:
undetectable
4d3aA-5xyiF:
18.08
4d3aB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
3 / 3 TYR L  88
THR L 103
GLU L  99
G  2 239 ( 4.4A)
U  2 238 ( 2.8A)
None
0.66A 4df3A-5xyiL:
undetectable
4df3A-5xyiL:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
3 / 3 TYR L  88
THR L 103
GLU L  99
G  2 239 ( 4.4A)
U  2 238 ( 2.8A)
None
0.66A 4df3B-5xyiL:
undetectable
4df3B-5xyiL:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 7 ALA E 119
GLY E  74
GLY E  91
ILE E  90
None
0.55A 4eatA-5xyiE:
undetectable
4eatA-5xyiE:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 7 LEU V  61
TYR V  57
ARG V  22
THR V  20
U  2 890 ( 4.3A)
None
None
None
0.89A 4eq4A-5xyiV:
undetectable
4eq4A-5xyiV:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 7 LEU V  61
TYR V  57
ARG V  22
THR V  20
U  2 890 ( 4.3A)
None
None
None
0.86A 4eqlA-5xyiV:
undetectable
4eqlA-5xyiV:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 7 LEU V  61
TYR V  57
ARG V  22
THR V  20
U  2 890 ( 4.3A)
None
None
None
0.91A 4eqlB-5xyiV:
undetectable
4eqlB-5xyiV:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
4 / 7 ILE T 107
LEU T 111
LYS T 125
GLY T 126
None
None
G  21177 ( 4.2A)
G  21306 ( 4.3A)
0.94A 4hbfA-5xyiT:
undetectable
4hbfA-5xyiT:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA501_1
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
5 / 12 ILE E 228
THR E 220
VAL E 208
ASP E 179
ILE E 195
None
A  2 601 ( 4.5A)
None
None
None
1.36A 4i41A-5xyiE:
undetectable
4i41A-5xyiE:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 ILE L 105
THR L 103
VAL L 137
ASP L 119
None
U  2 238 ( 2.8A)
None
None
1.13A 4iaqA-5xyiL:
undetectable
4iaqA-5xyiL:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 4imxA-5xyic:
undetectable
4imxB-5xyic:
undetectable
4imxA-5xyic:
12.87
4imxB-5xyic:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 4imxA-5xyiF:
undetectable
4imxB-5xyiF:
undetectable
4imxA-5xyiF:
18.12
4imxB-5xyiF:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.18A 4jksA-5xyiJ:
undetectable
4jksA-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.18A 4jksB-5xyiJ:
undetectable
4jksB-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.18A 4jkuA-5xyiJ:
undetectable
4jkuA-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 4jslA-5xyic:
undetectable
4jslB-5xyic:
undetectable
4jslA-5xyic:
12.84
4jslB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.95A 4jsmA-5xyic:
undetectable
4jsmB-5xyic:
undetectable
4jsmA-5xyic:
12.84
4jsmB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSM_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 4jsmA-5xyiF:
undetectable
4jsmB-5xyiF:
undetectable
4jsmA-5xyiF:
18.08
4jsmB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 5 LYS A  57
LEU A  58
GLU A  54
LEU V  78
None
1.12A 4k4yA-5xyiA:
undetectable
4k4yA-5xyiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 4 LYS A  57
LEU A  58
GLU A  54
LEU V  78
None
1.14A 4k4yE-5xyiA:
undetectable
4k4yE-5xyiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 5 LYS A  57
LEU A  58
GLU A  54
LEU V  78
None
1.14A 4k4yI-5xyiA:
undetectable
4k4yI-5xyiA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 4k5hA-5xyic:
undetectable
4k5hB-5xyic:
undetectable
4k5hA-5xyic:
12.84
4k5hB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5H_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 4k5hA-5xyiF:
undetectable
4k5hB-5xyiF:
undetectable
4k5hA-5xyiF:
18.08
4k5hB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 4k5iA-5xyic:
undetectable
4k5iB-5xyic:
undetectable
4k5iA-5xyic:
12.84
4k5iB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 4k5iA-5xyiF:
undetectable
4k5iB-5xyiF:
undetectable
4k5iA-5xyiF:
18.08
4k5iB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 4k5jA-5xyic:
undetectable
4k5jB-5xyic:
undetectable
4k5jA-5xyic:
12.84
4k5jB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 4k5jA-5xyiF:
undetectable
4k5jB-5xyiF:
undetectable
4k5jA-5xyiF:
18.08
4k5jB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 4k5kA-5xyic:
undetectable
4k5kB-5xyic:
undetectable
4k5kA-5xyic:
12.84
4k5kB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.20A 4k8kB-5xyiJ:
undetectable
4k8kB-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.17A 4kalA-5xyiJ:
undetectable
4kalA-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.18A 4kalB-5xyiJ:
undetectable
4kalB-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4kcpA-5xyiF:
undetectable
4kcpB-5xyiF:
undetectable
4kcpA-5xyiF:
18.08
4kcpB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4kcqA-5xyiF:
undetectable
4kcqB-5xyiF:
undetectable
4kcqA-5xyiF:
18.08
4kcqB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 4kcrA-5xyiF:
undetectable
4kcrB-5xyiF:
undetectable
4kcrA-5xyiF:
18.08
4kcrB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.00A 4kcsA-5xyiF:
undetectable
4kcsB-5xyiF:
undetectable
4kcsA-5xyiF:
18.08
4kcsB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 6 LEU V  61
TYR V  57
ARG V  22
THR V  20
U  2 890 ( 4.3A)
None
None
None
0.87A 4l39A-5xyiV:
undetectable
4l39A-5xyiV:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)
5xyi 40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis)
4 / 7 LEU V  61
TYR V  57
ARG V  22
THR V  20
U  2 890 ( 4.3A)
None
None
None
0.89A 4l39B-5xyiV:
undetectable
4l39B-5xyiV:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 SER J  96
LEU J  75
TYR J  93
PRO C 188
None
1.20A 4lcaA-5xyiJ:
undetectable
4lcaA-5xyiJ:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_1
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
5 / 12 LEU J  97
LEU J 102
ILE J  50
GLY J  82
LEU J  84
None
0.98A 4lmnA-5xyiJ:
undetectable
4lmnA-5xyiJ:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)
5xyi UNCHARACTERIZED
PROTEIN
RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 ASP W 112
TRP C 245
SER W  43
None
0.97A 4lrhB-5xyiW:
undetectable
4lrhB-5xyiW:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)
5xyi UNCHARACTERIZED
PROTEIN
RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 ASP W 112
TRP C 245
SER W  43
None
0.98A 4lrhF-5xyiW:
undetectable
4lrhF-5xyiW:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 4luwA-5xyic:
undetectable
4luwB-5xyic:
undetectable
4luwA-5xyic:
12.87
4luwB-5xyic:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 4luwA-5xyiF:
undetectable
4luwB-5xyiF:
undetectable
4luwA-5xyiF:
18.12
4luwB-5xyiF:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB304_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 4 GLY B  89
SER B  90
ARG B  26
PRO B  54
None
1.23A 4m93B-5xyiB:
0.0
4m93C-5xyiB:
0.0
4m93B-5xyiB:
22.71
4m93C-5xyiB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)
5xyi 40S RIBOSOMAL
PROTEIN S7, PUTATIVE

(Trichomonas
vaginalis)
4 / 8 ILE H  71
LEU H  58
LEU H  61
GLU H  62
None
0.83A 4mwzB-5xyiH:
undetectable
4mwzB-5xyiH:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.91A 4njuA-5xyiX:
undetectable
4njuA-5xyiX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.92A 4njuC-5xyiX:
undetectable
4njuC-5xyiX:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 11 ILE T  68
ALA T  64
LEU T  25
ALA T  26
LEU T 111
None
1.08A 4nqaA-5xyiT:
undetectable
4nqaA-5xyiT:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)
5xyi RIBOSOMAL PROTEIN
S15A
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 8 LEU C 240
ASN W  70
LEU W  66
ILE W  14
None
0.96A 4ok1A-5xyiC:
undetectable
4ok1A-5xyiC:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_A_SAMA301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)
5xyi 40S RIBOSOMAL
PROTEIN SA
UNCHARACTERIZED
PROTEIN
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis;
Trichomonas
vaginalis)
5 / 12 ALA C  74
GLY V  56
ALA V  60
ALA V  30
TYR A 154
None
None
G  2 891 ( 3.6A)
None
None
1.20A 4pclA-5xyiC:
undetectable
4pclA-5xyiC:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN
40S RIBOSOMAL
PROTEIN S21

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 ARG V  15
GLU C 252
TYR C  72
None
0.97A 4r29D-5xyiV:
undetectable
4r29D-5xyiV:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ILE F  89
PRO F  97
HIS F  35
VAL F 105
None
1.27A 4s0vA-5xyiF:
undetectable
4s0vA-5xyiF:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.01A 4uh7A-5xyiF:
0.8
4uh7B-5xyiF:
undetectable
4uh7A-5xyiF:
18.08
4uh7B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4uh8A-5xyiF:
undetectable
4uh8B-5xyiF:
undetectable
4uh8A-5xyiF:
18.08
4uh8B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 4uhaA-5xyiF:
undetectable
4uhaB-5xyiF:
undetectable
4uhaA-5xyiF:
18.08
4uhaB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 4upqA-5xyic:
undetectable
4upqB-5xyic:
undetectable
4upqA-5xyic:
12.84
4upqB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 4upqA-5xyiF:
undetectable
4upqB-5xyiF:
undetectable
4upqA-5xyiF:
18.08
4upqB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 CYH B 197
ILE B 200
GLN B 159
ILE B 117
None
1.15A 4w5qA-5xyiB:
undetectable
4w5qA-5xyiB:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 CYH B 197
ILE B 200
GLN B 159
ILE B 117
None
1.14A 4w5tA-5xyiB:
undetectable
4w5tA-5xyiB:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)
5xyi RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis)
5 / 12 LEU W  11
LEU W  69
LEU W  38
VAL W  25
ILE W  61
None
1.06A 4x1yD-5xyiW:
undetectable
4x1yD-5xyiW:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)
5xyi RIBOSOMAL PROTEIN
S13P/S18E, PUTATIVE

(Trichomonas
vaginalis)
5 / 9 LEU S 105
GLY S 106
ILE S  35
SER S  19
LEU S  18
None
1.21A 4x3mB-5xyiS:
undetectable
4x3mB-5xyiS:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 4 GLY B 205
VAL B 136
PHE B 184
ILE B 208
None
1.14A 4xv2B-5xyiB:
undetectable
4xv2B-5xyiB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 VAL T  35
TYR T  61
ALA T  64
None
0.44A 4ybnA-5xyiT:
undetectable
4ybnA-5xyiT:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 CYH B 197
ILE B 200
GLN B 159
ILE B 117
None
1.05A 4z4cA-5xyiB:
undetectable
4z4cA-5xyiB:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 ASP g 324
ALA g  35
THR g 307
TYR g 322
None
1.35A 4z4cA-5xyig:
undetectable
4z4cA-5xyig:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)
5xyi RIBOSOMAL PROTEIN
S3AE, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 CYH B 197
ILE B 200
GLN B 159
ILE B 117
None
1.15A 4z4dA-5xyiB:
undetectable
4z4dA-5xyiB:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 ASP g 324
ALA g  35
THR g 307
TYR g 322
None
1.31A 4z4fA-5xyig:
undetectable
4z4fA-5xyig:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ASP g 324
ALA g  35
THR g 307
TYR g 322
None
1.36A 4z4gA-5xyig:
undetectable
4z4gA-5xyig:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ASP g 324
ALA g  35
THR g 307
TYR g 322
None
1.36A 4z4hA-5xyig:
undetectable
4z4hA-5xyig:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 6 ASP g 324
ALA g  35
THR g 307
TYR g 322
None
1.31A 4z4iA-5xyig:
undetectable
4z4iA-5xyig:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ALA T  47
ARG T  63
HIS T  99
ALA T  88
None
G  21289 ( 4.0A)
A  21331 ( 4.2A)
A  21332 ( 4.9A)
1.18A 5a06C-5xyiT:
undetectable
5a06D-5xyiT:
undetectable
5a06C-5xyiT:
18.08
5a06D-5xyiT:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.96A 5adjA-5xyic:
undetectable
5adjB-5xyic:
undetectable
5adjA-5xyic:
12.84
5adjB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADJ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 5adjA-5xyiF:
undetectable
5adjB-5xyiF:
undetectable
5adjA-5xyiF:
18.08
5adjB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.99A 5adkA-5xyic:
undetectable
5adkB-5xyic:
undetectable
5adkA-5xyic:
12.84
5adkB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADK_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 5adkA-5xyiF:
undetectable
5adkB-5xyiF:
undetectable
5adkA-5xyiF:
18.08
5adkB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 5adlA-5xyiF:
undetectable
5adlB-5xyiF:
undetectable
5adlA-5xyiF:
18.08
5adlB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 5admA-5xyic:
undetectable
5admB-5xyic:
undetectable
5admA-5xyic:
12.84
5admB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 5admA-5xyiF:
undetectable
5admB-5xyiF:
undetectable
5admA-5xyiF:
18.08
5admB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 5adnA-5xyic:
undetectable
5adnB-5xyic:
undetectable
5adnA-5xyic:
12.84
5adnB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADN_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 5adnA-5xyiF:
undetectable
5adnB-5xyiF:
undetectable
5adnA-5xyiF:
18.08
5adnB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8I_C_FK5C201_2
(CALCINEURIN SUBUNIT
B, VARIANT
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 4 LEU Z  67
MET Z  34
VAL Z  38
ASN Z  41
None
1.36A 5b8iB-5xyiZ:
undetectable
5b8iB-5xyiZ:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)
5xyi 40S RIBOSOMAL
PROTEIN S16,
PUTATIVE
RIBOSOMAL PROTEIN
S10P/S20E, PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ARG Q 135
GLY Q 128
THR U  78
GLU U  79
U  21275 ( 3.5A)
None
U  21090 ( 3.6A)
C  21005 ( 3.5A)
1.09A 5btiC-5xyiQ:
undetectable
5btiD-5xyiQ:
undetectable
5btiC-5xyiQ:
15.50
5btiD-5xyiQ:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 5 PHE F  86
HIS F  35
LEU F  57
PRO F  97
None
1.42A 5csyB-5xyiF:
undetectable
5csyB-5xyiF:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 8 ILE R  17
VAL R  54
GLN R  23
CYH R  35
None
1.19A 5dqyA-5xyiR:
undetectable
5dqyA-5xyiR:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5xyi 40S RIBOSOMAL
PROTEIN S4

(Trichomonas
vaginalis)
4 / 6 PHE E 162
SER E 171
LEU E 123
LEU E 124
None
1.33A 5dzke-5xyiE:
undetectable
5dzks-5xyiE:
undetectable
5dzke-5xyiE:
21.40
5dzks-5xyiE:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
5xyi 40S RIBOSOMAL
PROTEIN S8

(Trichomonas
vaginalis)
5 / 12 ILE I 166
GLY I  63
THR I  76
ASN I  94
THR I  82
None
1.46A 5fhzA-5xyiI:
undetectable
5fhzA-5xyiI:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 5fj2A-5xyic:
undetectable
5fj2B-5xyic:
undetectable
5fj2A-5xyic:
12.84
5fj2B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 5fj2A-5xyiF:
undetectable
5fj2B-5xyiF:
undetectable
5fj2A-5xyiF:
18.08
5fj2B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 5fj3A-5xyic:
undetectable
5fj3B-5xyic:
undetectable
5fj3A-5xyic:
12.84
5fj3B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 5fj3A-5xyiF:
undetectable
5fj3B-5xyiF:
undetectable
5fj3A-5xyiF:
18.08
5fj3B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 ARG g  75
VAL g  49
TRP g  60
None
1.16A 5fvoA-5xyig:
undetectable
5fvoA-5xyig:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 5fvyA-5xyic:
undetectable
5fvyB-5xyic:
undetectable
5fvyA-5xyic:
12.84
5fvyB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.92A 5fvyA-5xyiF:
undetectable
5fvyB-5xyiF:
undetectable
5fvyA-5xyiF:
18.08
5fvyB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)
5xyi 40S RIBOSOMAL
PROTEIN S17-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 8 THR R  55
LEU R  57
ILE R  17
LEU R  61
C  21198 ( 3.9A)
None
None
None
0.93A 5g48A-5xyiR:
undetectable
5g48A-5xyiR:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ASP g  54
ALA g  34
GLY g 321
SER g 320
SER g  52
G  21218 ( 4.9A)
None
None
None
None
1.27A 5hfjE-5xyig:
undetectable
5hfjE-5xyig:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
3 / 3 VAL g 184
GLN g 145
CYH g 161
None
0.84A 5icxC-5xyig:
undetectable
5icxF-5xyig:
undetectable
5icxC-5xyig:
19.94
5icxF-5xyig:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGI_A_ZITA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
5xyi 40S RIBOSOMAL
PROTEIN S13,
PUTATIVE

(Trichomonas
vaginalis)
4 / 6 HIS N  90
GLU N  87
ALA N  81
LEU N  75
G  2 689 ( 3.5A)
G  2 687 ( 3.9A)
U  2 658 ( 3.7A)
None
1.02A 5igiA-5xyiN:
2.3
5igiA-5xyiN:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5INZ_D_DVAD15_0
(THETA DEFENSIN-2,
D-PEPTIDE
THETA DEFENSIN-2,
L-PEPTIDE)
5xyi 40S RIBOSOMAL
PROTEIN S27

(Trichomonas
vaginalis)
3 / 3 GLY b  43
CYH b  41
CYH b  38
None
0.95A 5inzB-5xyib:
undetectable
5inzB-5xyib:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
5xyi RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis)
4 / 5 ILE Y  56
ILE Y   8
HIS Y   7
VAL Y   6
None
A  2 628 ( 4.5A)
C  2 626 ( 4.1A)
None
0.97A 5jmnA-5xyiY:
undetectable
5jmnA-5xyiY:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
3 / 3 VAL O 140
HIS O 102
VAL O  38
None
0.58A 5jmnC-5xyiO:
undetectable
5jmnC-5xyiO:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 12 THR O  60
GLY O  26
PRO O  27
VAL O  28
LEU O  96
None
1.05A 5jo9A-5xyiO:
undetectable
5jo9A-5xyiO:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 10 ALA O 126
ALA O 120
GLY O 119
ALA O  82
THR O  48
None
1.09A 5lf3H-5xyiO:
undetectable
5lf3I-5xyiO:
undetectable
5lf3H-5xyiO:
24.78
5lf3I-5xyiO:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 10 ALA O 126
ALA O 120
GLY O 119
ALA O  82
THR O  48
None
1.09A 5lf3V-5xyiO:
undetectable
5lf3W-5xyiO:
undetectable
5lf3V-5xyiO:
24.78
5lf3W-5xyiO:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 11 ALA O 126
ALA O 120
GLY O 119
ALA O  82
THR O  48
None
1.08A 5lf7H-5xyiO:
undetectable
5lf7I-5xyiO:
undetectable
5lf7H-5xyiO:
24.78
5lf7I-5xyiO:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
5 / 11 ALA O 126
ALA O 120
GLY O 119
ALA O  82
THR O  48
None
1.06A 5lf7V-5xyiO:
undetectable
5lf7W-5xyiO:
undetectable
5lf7V-5xyiO:
24.78
5lf7W-5xyiO:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
3 / 3 HIS X  19
ASN X  22
ALA X  25
G  2 532 ( 3.9A)
G  2 917 ( 3.6A)
G  2 917 ( 3.1A)
0.80A 5n4tB-5xyiX:
undetectable
5n4tB-5xyiX:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 8 ASN J  63
ARG J  67
ILE J  68
GLY J  71
None
0.92A 5nzxA-5xyiJ:
undetectable
5nzxA-5xyiJ:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.91A 5uanA-5xyiT:
undetectable
5uanA-5xyiT:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
LEU T  25
ALA T  26
LEU T 111
None
0.91A 5uanA-5xyiT:
undetectable
5uanA-5xyiT:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.05A 5uo8C-5xyiF:
undetectable
5uo8D-5xyiF:
undetectable
5uo8C-5xyiF:
18.69
5uo8D-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.02A 5uo9A-5xyic:
undetectable
5uo9B-5xyic:
undetectable
5uo9A-5xyic:
10.11
5uo9B-5xyic:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 5uo9A-5xyiF:
undetectable
5uo9B-5xyiF:
undetectable
5uo9A-5xyiF:
18.69
5uo9B-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 5uo9C-5xyic:
undetectable
5uo9D-5xyic:
undetectable
5uo9C-5xyic:
10.11
5uo9D-5xyic:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.03A 5uodA-5xyic:
undetectable
5uodB-5xyic:
undetectable
5uodA-5xyic:
12.84
5uodB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.03A 5uodA-5xyiF:
undetectable
5uodB-5xyiF:
undetectable
5uodA-5xyiF:
18.08
5uodB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 5vv6A-5xyiF:
undetectable
5vv6B-5xyiF:
undetectable
5vv6A-5xyiF:
18.08
5vv6B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.02A 5vv7A-5xyiF:
undetectable
5vv7B-5xyiF:
undetectable
5vv7A-5xyiF:
18.08
5vv7B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 5vv8A-5xyiF:
undetectable
5vv8B-5xyiF:
undetectable
5vv8A-5xyiF:
18.08
5vv8B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 5vv9A-5xyic:
undetectable
5vv9B-5xyic:
undetectable
5vv9A-5xyic:
12.84
5vv9B-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV9_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 5vv9A-5xyiF:
undetectable
5vv9B-5xyiF:
1.7
5vv9A-5xyiF:
18.08
5vv9B-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.93A 5vvaA-5xyic:
undetectable
5vvaB-5xyic:
undetectable
5vvaA-5xyic:
12.84
5vvaB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVA_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.02A 5vvaA-5xyiF:
undetectable
5vvaB-5xyiF:
undetectable
5vvaA-5xyiF:
18.08
5vvaB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.04A 5vvbC-5xyiF:
undetectable
5vvbD-5xyiF:
0.0
5vvbC-5xyiF:
18.69
5vvbD-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 5vvdA-5xyiF:
undetectable
5vvdB-5xyiF:
undetectable
5vvdA-5xyiF:
18.69
5vvdB-5xyiF:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.00A 5vvgA-5xyic:
undetectable
5vvgB-5xyic:
undetectable
5vvgA-5xyic:
12.84
5vvgB-5xyic:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 5vvgA-5xyiF:
undetectable
5vvgB-5xyiF:
undetectable
5vvgA-5xyiF:
18.08
5vvgB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 5vvnA-5xyiF:
undetectable
5vvnB-5xyiF:
undetectable
5vvnA-5xyiF:
18.08
5vvnB-5xyiF:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)
5xyi UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 ARG J  51
PHE C 212
ARG J  55
None
A  2   1 ( 3.3A)
None
0.81A 5y9yA-5xyiJ:
undetectable
5y9yA-5xyiJ:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.98A 5z12B-5xyiT:
undetectable
5z12B-5xyiT:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.99A 5z12C-5xyiT:
undetectable
5z12C-5xyiT:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
LEU T  25
ALA T  26
LEU T 111
None
1.03A 5z12C-5xyiT:
undetectable
5z12C-5xyiT:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)
5xyi 40S RIBOSOMAL
PROTEIN SA
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 8 ARG A 118
GLU A 116
PRO C  76
ILE C  82
None
1.13A 6a4iA-5xyiA:
undetectable
6a4iA-5xyiA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)
5xyi RIBOSOMAL PROTEIN
S19E, PUTATIVE

(Trichomonas
vaginalis)
5 / 12 ILE T  68
ALA T  65
ALA T  64
LEU T  25
ALA T  26
None
0.98A 6a5yD-5xyiT:
undetectable
6a5yD-5xyiT:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE

(Trichomonas
vaginalis)
4 / 6 LYS F 182
ARG F 187
GLU F 186
ALA F 189
None
1.04A 6an0A-5xyiF:
undetectable
6an0A-5xyiF:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.97A 6av6A-5xyic:
undetectable
6av6B-5xyic:
undetectable
6av6A-5xyic:
22.47
6av6B-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.92A 6av6C-5xyic:
undetectable
6av6D-5xyic:
undetectable
6av6C-5xyic:
22.47
6av6D-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 7 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.96A 6av7A-5xyic:
undetectable
6av7B-5xyic:
undetectable
6av7A-5xyic:
22.47
6av7B-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.98A 6av7A-5xyiF:
undetectable
6av7B-5xyiF:
undetectable
6av7A-5xyiF:
16.32
6av7B-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.92A 6av7C-5xyic:
undetectable
6av7D-5xyic:
undetectable
6av7C-5xyic:
22.47
6av7D-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.03A 6av7C-5xyiF:
undetectable
6av7D-5xyiF:
undetectable
6av7C-5xyiF:
16.32
6av7D-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')
5xyi 40S RIBOSOMAL
PROTEIN S4
RIBOSOMAL PROTEIN
S24E, PUTATIVE

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
3 / 3 ARG E  51
LYS E  53
ARG Y  89
None
1.25A 6c06D-5xyiE:
undetectable
6c06D-5xyiE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)
5xyi 40S RIBOSOMAL
PROTEIN S7, PUTATIVE
40S RIBOSOMAL
PROTEIN S13,
PUTATIVE
RIBOSOMAL PROTEIN
S15A

(Trichomonas
vaginalis;
Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 8 HIS W  56
LEU H 106
ILE H 115
ARG N  20
None
0.94A 6cb4A-5xyiW:
undetectable
6cb4A-5xyiW:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.98A 6cieA-5xyic:
undetectable
6cieB-5xyic:
undetectable
6cieA-5xyic:
22.47
6cieB-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 7 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.97A 6cieA-5xyiF:
undetectable
6cieB-5xyiF:
undetectable
6cieA-5xyiF:
16.32
6cieB-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_C_H4BC502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.93A 6cieC-5xyic:
undetectable
6cieD-5xyic:
undetectable
6cieC-5xyic:
22.47
6cieD-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.02A 6cieC-5xyiF:
undetectable
6cieD-5xyiF:
undetectable
6cieC-5xyiF:
16.32
6cieD-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_A_H4BA502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
0.90A 6cifA-5xyic:
undetectable
6cifB-5xyic:
undetectable
6cifA-5xyic:
22.47
6cifB-5xyic:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
1.02A 6cifA-5xyiF:
undetectable
6cifB-5xyiF:
undetectable
6cifA-5xyiF:
16.32
6cifB-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_D_H4BD502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis;
Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.96A 6cifC-5xyiF:
undetectable
6cifD-5xyiF:
undetectable
6cifC-5xyiF:
16.32
6cifD-5xyiF:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 7 TYR g 322
TRP g 330
CYH g 267
LEU g 318
None
1.35A 6cnjA-5xyig:
undetectable
6cnjB-5xyig:
undetectable
6cnjA-5xyig:
15.36
6cnjB-5xyig:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNK_B_NCTB402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)
5xyi GUANINE
NUCLEOTIDE-BINDING
PROTEIN BETA
SUBUNIT, PUTATIVE

(Trichomonas
vaginalis)
4 / 7 TYR g 322
TRP g 330
CYH g 267
LEU g 318
None
1.31A 6cnkB-5xyig:
undetectable
6cnkC-5xyig:
undetectable
6cnkB-5xyig:
15.36
6cnkC-5xyig:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.97A 6dh0A-5xyiX:
undetectable
6dh0A-5xyiX:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis)
5 / 12 LEU X  75
ALA X  84
VAL X  52
ILE X  95
ILE X 124
None
None
None
None
C  2  27 ( 4.6A)
0.91A 6dilA-5xyiX:
undetectable
6dilA-5xyiX:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)
5xyi 40S RIBOSOMAL
PROTEIN S21
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 5 LEU V  23
LEU V  12
THR C 236
PRO C 166
None
1.07A 6ew0F-5xyiV:
undetectable
6ew0F-5xyiV:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
6 / 10 ARG J  51
VAL J  94
ALA J  54
LEU J  97
LEU J  47
LEU J  78
None
1.40A 6f6nA-5xyiJ:
undetectable
6f6nB-5xyiJ:
undetectable
6f6nA-5xyiJ:
18.87
6f6nB-5xyiJ:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FI4_B_DVAB8_0
(14-3-3 PROTEIN SIGMA
PRO-SEP-LEU-PRO-DVA)
5xyi UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 5 SER L  63
VAL L  62
ASN L 136
PRO L 128
A  2 104 ( 2.6A)
None
None
U  2 265 ( 3.4A)
1.26A 6fi4A-5xyiL:
undetectable
6fi4B-5xyiL:
undetectable
6fi4A-5xyiL:
21.79
6fi4B-5xyiL:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)
5xyi RIBOSOMAL PROTEIN
S14

(Trichomonas
vaginalis)
4 / 7 SER O 122
ALA O  86
ILE O  68
ALA O  69
None
0.96A 6ma7A-5xyiO:
undetectable
6ma7A-5xyiO:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5xyi PLECTIN/S10 DOMAIN
CONTAINING PROTEIN

(Trichomonas
vaginalis)
3 / 3 ARG K   8
LEU K  12
PHE K  16
U  21065 ( 4.1A)
None
None
0.59A 6nknP-5xyiK:
undetectable
6nknP-5xyiK:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 VAL c  16
ARG F  49
PHE F  50
GLU c  51
None
C  21421 ( 4.4A)
None
None
1.01A 8nseA-5xyic:
undetectable
8nseB-5xyic:
undetectable
8nseA-5xyic:
12.80
8nseB-5xyic:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
8NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.95A 8nseA-5xyiF:
undetectable
8nseB-5xyiF:
undetectable
8nseA-5xyiF:
18.04
8nseB-5xyiF:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
9NSE_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis)
4 / 6 PHE F  50
GLU c  51
VAL c  16
ARG F  49
None
None
None
C  21421 ( 4.4A)
0.99A 9nseA-5xyiF:
undetectable
9nseB-5xyiF:
undetectable
9nseA-5xyiF:
18.04
9nseB-5xyiF:
18.04