SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xyu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6O_B_SAMB500_0 (HYPOTHETICAL PROTEIN)	5xyu	30S RIBOSOMAL PROTEIN S6 (Mycolicibacteriu m smegmatis)	4 / 6	ASP F 58 VAL F 34 PRO F 6 THR F 7	None	1.38A	2q6oB-5xyuF: undetectable	2q6oB-5xyuF: 16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K36_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	5xyu	30S RIBOSOMAL PROTEIN S7 (Mycolicibacteriu m smegmatis)	5 / 12	ASN G 106 SER G 108 LEU G 120 ILE G 42 LEU G 38	C A 922 ( 4.9A) None None U A1221 ( 3.6A) G A1222 ( 4.1A)	1.34A	4k36A-5xyuG: undetectable	4k36A-5xyuG: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K37_B_SAMB504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	5xyu	30S RIBOSOMAL PROTEIN S7 (Mycolicibacteriu m smegmatis)	5 / 11	ASN G 106 SER G 108 LEU G 120 ILE G 42 LEU G 38	C A 922 ( 4.9A) None None U A1221 ( 3.6A) G A1222 ( 4.1A)	1.24A	4k37B-5xyuG: undetectable	4k37B-5xyuG: 18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K39_A_SAMA504_0 (ANAEROBIC SULFATASE-MATURATING ENZYME)	5xyu	30S RIBOSOMAL PROTEIN S7 (Mycolicibacteriu m smegmatis)	5 / 12	ASN G 106 SER G 108 LEU G 120 ILE G 42 LEU G 38	C A 922 ( 4.9A) None None U A1221 ( 3.6A) G A1222 ( 4.1A)	1.26A	4k39A-5xyuG: undetectable	4k39A-5xyuG: 18.23

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2Q6O_B_SAMB500_0","HYPOTHETICAL PROTEIN","5xyu","30S RIBOSOMAL PROTEIN S6","Mycolicibacterium smegmatis",4,"ASP F  58;VAL F  34;PRO F   6;THR F   7","None","1.38A","2q6oB-5xyuF:undetectable","2q6oB-5xyuF:16.25"],["4K36_A_SAMA504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","5xyu","30S RIBOSOMAL PROTEIN S7","Mycolicibacterium smegmatis",5,"ASN G 106;SER G 108;LEU G 120;ILE G  42;LEU G  38","  C A 922 ( 4.9A);None;None;  U A1221 ( 3.6A);  G A1222 ( 4.1A)","1.34A","4k36A-5xyuG:undetectable","4k36A-5xyuG:17.42"],["4K37_B_SAMB504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","5xyu","30S RIBOSOMAL PROTEIN S7","Mycolicibacterium smegmatis",5,"ASN G 106;SER G 108;LEU G 120;ILE G  42;LEU G  38","  C A 922 ( 4.9A);None;None;  U A1221 ( 3.6A);  G A1222 ( 4.1A)","1.24A","4k37B-5xyuG:undetectable","4k37B-5xyuG:18.23"],["4K39_A_SAMA504_0","ANAEROBIC SULFATASE-MATURATING ENZYME","5xyu","30S RIBOSOMAL PROTEIN S7","Mycolicibacterium smegmatis",5,"ASN G 106;SER G 108;LEU G 120;ILE G  42;LEU G  38","  C A 922 ( 4.9A);None;None;  U A1221 ( 3.6A);  G A1222 ( 4.1A)","1.26A","4k39A-5xyuG:undetectable","4k39A-5xyuG:18.23"]]