SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xyw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5xyw RHINO
(Drosophila
simulans) 		5 / 11 PRO A 475
ILE A 479
VAL A 463
PHE A 462
VAL A 450
 None
 1.36A 3rf4B-5xywA:
undetectable
3rf4C-5xywA:
undetectable		 3rf4B-5xywA:
15.65
3rf4C-5xywA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5xyw RHINO
GD21652
(Drosophila
simulans;
Drosophila
simulans) 		5 / 12 THR C  21
THR C  22
ILE A 479
VAL A 463
ASP A 472
 None
 0.95A 6emuC-5xywC:
undetectable		 6emuC-5xywC:
undetectable