SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xz3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		3 / 4 LYS A  22
ALA A  21
MET A  62
 None
 1.07A 1hk3A-5xz3A:
undetectable		 1hk3A-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		5 / 12 ILE A  76
LEU A  75
HIS A  37
GLY A 109
ILE A  57
 None
 0.98A 1kyvB-5xz3A:
undetectable
1kyvC-5xz3A:
undetectable		 1kyvB-5xz3A:
undetectable
1kyvC-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		5 / 12 ILE A  76
LEU A  75
HIS A  37
GLY A 109
ILE A  57
 None
 0.99A 1kyvD-5xz3A:
undetectable
1kyvE-5xz3A:
undetectable		 1kyvD-5xz3A:
undetectable
1kyvE-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		4 / 5 ILE A  76
TYR A  72
ILE A  36
HIS A 125
 None
 1.08A 3eteB-5xz3A:
undetectable
3eteC-5xz3A:
undetectable		 3eteB-5xz3A:
undetectable
3eteC-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		4 / 7 TYR A  72
ILE A  70
GLY A  87
TYR A  26
 None
 0.90A 4iqqB-5xz3A:
undetectable		 4iqqB-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URN_A_NOVA2000_1
(DNA TOPOISOMERASE
IV, B SUBUNIT)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		5 / 11 ASN A  53
SER A  52
GLU A  55
ARG A  58
ARG A  13
 None
 1.42A 4urnA-5xz3A:
undetectable		 4urnA-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		5 / 12 ASN A  53
SER A  52
GLU A  55
ARG A  58
ARG A  13
 None
 1.35A 4uroA-5xz3A:
undetectable		 4uroA-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		4 / 7 TYR A  33
ILE A 144
ILE A  35
ILE A 150
 None
 0.65A 5murB-5xz3A:
undetectable		 5murB-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		4 / 7 TYR A  72
ILE A  70
GLY A  87
TYR A  26
 None
 0.87A 5nooA-5xz3A:
undetectable		 5nooA-5xz3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5xz3 PEPTIDOGLYCAN-RECOGN
ITION PROTEIN
(Apis
mellifera) 		4 / 7 TYR A  72
ILE A  70
GLY A  87
TYR A  26
 None
 0.87A 5nooB-5xz3A:
undetectable		 5nooB-5xz3A:
undetectable