SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xzq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5xzq HYDROXYNITRILE LYASE
(Passiflora
edulis) 		5 / 10 PHE A  77
PHE A  86
ALA A  87
ILE A  97
VAL A  99
 None
 1.00A 3me6A-5xzqA:
undetectable		 3me6A-5xzqA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5xzq HYDROXYNITRILE LYASE
(Passiflora
edulis) 		3 / 3 TYR A  14
TYR A  64
GLU A  89
 None
 0.93A 3pfgA-5xzqA:
undetectable		 3pfgA-5xzqA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5xzq HYDROXYNITRILE LYASE
(Passiflora
edulis) 		5 / 12 PHE A  68
SER A  66
PHE A  91
VAL A  99
ALA A  83
 None
 1.17A 3u9fG-5xzqA:
undetectable
3u9fH-5xzqA:
undetectable		 3u9fG-5xzqA:
18.10
3u9fH-5xzqA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5xzq HYDROXYNITRILE LYASE
(Passiflora
edulis) 		4 / 5 ILE A  26
PHE A  90
TYR A  64
THR A  47
 None
 1.24A 5z84N-5xzqA:
undetectable
5z84W-5xzqA:
undetectable		 5z84N-5xzqA:
13.23
5z84W-5xzqA:
18.71