SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5xzu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 11 ASP A 132
ARG A  83
VAL A 201
ILE A 200
PHE A 164
 None
 1.20A 1fkfA-5xzuA:
undetectable		 1fkfA-5xzuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 GLN A  69
THR A  56
TRP A 131
 None
 0.95A 2rctA-5xzuA:
undetectable		 2rctA-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 VAL A 252
TRP A 289
TRP A 297
 None
CBI  A 404 (-4.0A)
CBI  A 404 (-4.2A)
 1.40A 2xdcA-5xzuA:
undetectable
2xdcB-5xzuA:
undetectable		 2xdcA-5xzuA:
undetectable
2xdcB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 TRP A 297
VAL A 252
TRP A 289
 CBI  A 404 (-4.2A)
None
CBI  A 404 (-4.0A)
 1.42A 2xdcA-5xzuA:
undetectable
2xdcB-5xzuA:
undetectable		 2xdcA-5xzuA:
undetectable
2xdcB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 11 SER A 145
TYR A 182
ALA A 196
GLY A 144
ALA A 143
 None
 1.34A 2xh9A-5xzuA:
undetectable		 2xh9A-5xzuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 10 SER A 145
TYR A 182
ALA A 196
GLY A 144
ALA A 143
 None
 1.36A 2xh9B-5xzuA:
undetectable		 2xh9B-5xzuA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 VAL A 252
TRP A 289
TRP A 297
 None
CBI  A 404 (-4.0A)
CBI  A 404 (-4.2A)
 1.41A 2y5mA-5xzuA:
undetectable
2y5mB-5xzuA:
undetectable		 2y5mA-5xzuA:
undetectable
2y5mB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 4 VAL A 288
TRP A 297
VAL A 252
TRP A 289
 None
CBI  A 404 (-4.2A)
None
CBI  A 404 (-4.0A)
 1.41A 2y5mA-5xzuA:
undetectable
2y5mB-5xzuA:
undetectable		 2y5mA-5xzuA:
undetectable
2y5mB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 VAL A 252
TRP A 289
TRP A 297
 None
CBI  A 404 (-4.0A)
CBI  A 404 (-4.2A)
 1.41A 2y6nA-5xzuA:
undetectable
2y6nB-5xzuA:
undetectable		 2y6nA-5xzuA:
undetectable
2y6nB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 TRP A 297
VAL A 252
TRP A 289
 CBI  A 404 (-4.2A)
None
CBI  A 404 (-4.0A)
 1.41A 2y6nA-5xzuA:
undetectable
2y6nB-5xzuA:
undetectable		 2y6nA-5xzuA:
undetectable
2y6nB-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 6 GLU A 249
ASP A 290
ASN A  49
GLU A  92
 CBI  A 404 (-2.7A)
None
CBI  A 404 (-3.2A)
CBI  A 404 (-3.8A)
 1.08A 3vywA-5xzuA:
undetectable		 3vywA-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 GLU A 249
ASP A 290
ASN A  49
GLU A  92
 CBI  A 404 (-2.7A)
None
CBI  A 404 (-3.2A)
CBI  A 404 (-3.8A)
 1.08A 3vywD-5xzuA:
1.5		 3vywD-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 292
GLY A 316
TYR A 295
ASP A  29
 None
 1.08A 3w9tB-5xzuA:
undetectable		 3w9tB-5xzuA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 292
GLY A 316
TYR A 295
ASP A  29
 None
 1.07A 3w9tC-5xzuA:
undetectable		 3w9tC-5xzuA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 292
GLY A 316
TYR A 295
ASP A  29
 None
 1.06A 3w9tD-5xzuA:
undetectable		 3w9tD-5xzuA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 292
GLY A 316
TYR A 295
ASP A  29
 None
 1.07A 3w9tE-5xzuA:
undetectable		 3w9tE-5xzuA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 292
GLY A 316
TYR A 295
ASP A  29
 None
 1.07A 3w9tG-5xzuA:
undetectable		 3w9tG-5xzuA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 VAL A 252
TRP A 289
TRP A 297
 None
CBI  A 404 (-4.0A)
CBI  A 404 (-4.2A)
 1.38A 3zq8A-5xzuA:
undetectable
3zq8B-5xzuA:
undetectable		 3zq8A-5xzuA:
undetectable
3zq8B-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 TRP A 297
VAL A 288
TRP A 289
 CBI  A 404 (-4.2A)
None
CBI  A 404 (-4.0A)
 0.96A 3zq8C-5xzuA:
undetectable
3zq8D-5xzuA:
undetectable		 3zq8C-5xzuA:
undetectable
3zq8D-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 10 ASP A 132
ARG A  83
VAL A 201
ILE A 200
PHE A 164
 None
 1.23A 4dz3B-5xzuA:
undetectable		 4dz3B-5xzuA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 10 ASP A 184
VAL A 201
TYR A 182
PHE A 238
GLY A 213
 None
 1.39A 4mm7A-5xzuA:
undetectable		 4mm7A-5xzuA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 4 ALA A 272
ALA A 275
ALA A 276
ALA A 279
 None
 0.12A 4oadA-5xzuA:
undetectable		 4oadA-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 4 ALA A 272
ALA A 275
ALA A 276
ALA A 279
 None
 0.12A 4oaeA-5xzuA:
undetectable		 4oaeA-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 SER A 296
ASP A 293
GLN A 266
 None
 0.86A 4oltA-5xzuA:
undetectable
4oltB-5xzuA:
undetectable		 4oltA-5xzuA:
16.19
4oltB-5xzuA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 GLN A 266
SER A 296
ASP A 293
 None
 0.82A 4qwpA-5xzuA:
undetectable
4qwpB-5xzuA:
undetectable		 4qwpA-5xzuA:
16.19
4qwpB-5xzuA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 12 ILE A 286
LEU A  14
VAL A 245
LEU A 250
MET A 235
 None
 1.20A 5bykA-5xzuA:
undetectable		 5bykA-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 8 ILE A 221
GLN A 266
TYR A 270
VAL A 298
 None
 1.17A 5vlmF-5xzuA:
1.0		 5vlmF-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		4 / 5 ASP A 290
ILE A  50
ASN A  38
TYR A  32
 None
 0.91A 6a93B-5xzuA:
undetectable		 6a93B-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B52_A_OAQA302_0
(SULFOTRANSFERASE)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 12 ILE A 286
LEU A  14
VAL A 245
LEU A 250
MET A 235
 None
 1.23A 6b52A-5xzuA:
undetectable		 6b52A-5xzuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		5 / 12 PHE A 238
ASN A 234
ASP A 184
GLY A 215
ILE A 200
 None
 1.10A 6dwnA-5xzuA:
undetectable		 6dwnA-5xzuA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5xzu BETA-XYLANASE
(Bispora
sp.
MEY-1) 		3 / 3 LYS A 193
SER A 145
SER A 139
 None
 1.14A 6gbfA-5xzuA:
undetectable		 6gbfA-5xzuA:
undetectable