SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y00'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		5 / 10 TYR A 115
THR A 100
ASP A 183
VAL A 186
HIS A  74
 CRQ  A  70 ( 4.4A)
None
None
None
CRQ  A  70 ( 4.1A)
 1.30A 1ivvA-5y00A:
undetectable		 1ivvA-5y00A:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		5 / 10 TYR A 115
THR A 100
ASP A 183
VAL A 186
HIS A  74
 CRQ  A  70 ( 4.4A)
None
None
None
CRQ  A  70 ( 4.1A)
 1.28A 1ivvB-5y00A:
undetectable		 1ivvB-5y00A:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		4 / 7 GLY A  37
PHE A  87
PHE A  73
PHE A  47
 None
None
CRQ  A  70 ( 3.8A)
CRQ  A  70 ( 4.7A)
 1.04A 3ko0L-5y00A:
undetectable
3ko0N-5y00A:
undetectable		 3ko0L-5y00A:
21.90
3ko0N-5y00A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		5 / 10 VAL A  35
ALA A  66
TYR A  52
ILE A 219
ILE A  22
 None
 1.17A 3retA-5y00A:
undetectable
3retB-5y00A:
undetectable		 3retA-5y00A:
17.65
3retB-5y00A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		4 / 5 LEU A  69
LEU A  24
MET A  60
THR A 111
 CRQ  A  70 ( 4.3A)
None
None
None
 1.42A 4do3A-5y00A:
undetectable		 4do3A-5y00A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		4 / 5 GLY A  45
ALA A 225
PHE A  76
GLU A 223
 None
None
None
CRQ  A  70 ( 2.7A)
 1.04A 4m93B-5y00A:
undetectable
4m93C-5y00A:
undetectable		 4m93B-5y00A:
undetectable
4m93C-5y00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		3 / 3 ASP A 214
HIS A  50
LYS A 210
 None
 0.95A 4qzuD-5y00A:
undetectable		 4qzuD-5y00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		4 / 5 TYR A 238
HIS A 157
LEU A 164
PRO A 197
 GOL  A 302 ( 4.4A)
None
None
None
 1.39A 5csyB-5y00A:
undetectable		 5csyB-5y00A:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 5y00 GREEN FLUORESCENT
PROTEIN
(Olindias) 		3 / 3 VAL A 186
GLN A  88
CYH A  90
 None
 0.92A 5icxC-5y00A:
undetectable
5icxF-5y00A:
undetectable		 5icxC-5y00A:
16.59
5icxF-5y00A:
13.64