SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5y1z DREBRIN
(Homo
sapiens) 		5 / 9 TRP A  29
PHE A  58
ALA A  44
LEU A  31
GLY A  66
 None
 1.33A 2wscA-5y1zA:
undetectable		 2wscA-5y1zA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5y1z DREBRIN
(Homo
sapiens) 		5 / 9 TRP A  29
PHE A  58
ALA A  44
LEU A  31
GLY A  66
 None
 1.33A 2wseA-5y1zA:
undetectable		 2wseA-5y1zA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5y1z DREBRIN
(Homo
sapiens) 		5 / 9 TRP A  29
PHE A  58
ALA A  44
LEU A  31
GLY A  66
 None
 1.34A 2wsfA-5y1zA:
undetectable		 2wsfA-5y1zA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5y1z DREBRIN
(Homo
sapiens) 		5 / 9 TRP A  29
PHE A  58
ALA A  44
LEU A  31
GLY A  66
 None
 1.38A 3lw5A-5y1zA:
undetectable		 3lw5A-5y1zA:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5y1z PROTEIN KINASE
C-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 ILE C 242
ALA C 217
HIS C  95
ARG C 108
 None
 1.36A 4ac9B-5y1zC:
undetectable
4ac9C-5y1zC:
undetectable		 4ac9B-5y1zC:
19.41
4ac9C-5y1zC:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 5y1z PROTEIN KINASE
C-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 6 LEU C 158
LEU C 157
ILE C 252
MET C 249
 None
 0.98A 4ww7A-5y1zC:
undetectable		 4ww7A-5y1zC:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5y1z DREBRIN
PROTEIN KINASE
C-BINDING PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		4 / 7 ALA A   2
LYS C 243
GLU C 246
HIS C 247
 None
 1.01A 5ecnA-5y1zA:
undetectable		 5ecnA-5y1zA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 5y1z PROTEIN KINASE
C-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 5 VAL C 100
HIS C  95
LEU C 115
ASP C  88
 None
 1.44A 5vcvA-5y1zC:
undetectable		 5vcvA-5y1zC:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5y1z PROTEIN KINASE
C-BINDING PROTEIN 1
(Homo
sapiens) 		4 / 8 VAL C 177
CYH C 224
TYR C 227
ASN C 228
 None
 0.53A 5y1yA-5y1zC:
10.9		 5y1yA-5y1zC:
16.46