SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y2a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 9 TYR A2063
PHE A2094
GLY A2137
ASP A2178
MET A2248
TYR A2250
ASP A2251
TRP A2398
 None
 0.75A 1e9lA-5y2aA:
52.7		 1e9lA-5y2aA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 MET A2390
LEU A2392
GLY A2394
VAL A2060
LEU A2247
 None
 1.02A 1nhzA-5y2aA:
undetectable		 1nhzA-5y2aA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		3 / 3 LEU A2217
HIS A2089
LYS A2130
 None
 1.06A 1y7iA-5y2aA:
2.2		 1y7iA-5y2aA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 PHE A2094
GLY A2137
ASP A2178
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.78A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A2063
PHE A2094
GLY A2137
GLU A2180
ASP A2251
TYR A2303
TRP A2398
 None
 0.81A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A2063
PHE A2094
GLY A2137
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.56A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A2063
PHE A2094
GLY A2137
TRP A2138
GLU A2180
ASP A2251
TRP A2398
 None
 0.82A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A2063
PHE A2094
GLY A2137
TRP A2138
GLU A2180
MET A2248
TYR A2250
ASP A2251
 None
 0.66A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A2138
GLU A2180
TYR A2181
 None
 0.47A 2a3aA-5y2aA:
11.9		 2a3aA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 9 PHE A2094
GLY A2137
GLU A2180
ASP A2251
TYR A2303
TRP A2398
 None
 0.75A 2a3aB-5y2aA:
43.4		 2a3aB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 9 PHE A2094
GLY A2137
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.49A 2a3aB-5y2aA:
43.4		 2a3aB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A2063
PHE A2094
GLY A2137
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.60A 2a3bA-5y2aA:
43.2		 2a3bA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 10 PHE A2094
GLY A2137
ASP A2178
GLU A2180
MET A2248
TYR A2250
 None
 1.05A 2a3bB-5y2aA:
43.3		 2a3bB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 10 PHE A2094
GLY A2137
ASP A2178
MET A2248
TYR A2250
TYR A2303
 None
 0.88A 2a3bB-5y2aA:
43.3		 2a3bB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 10 PHE A2094
GLY A2137
ASP A2178
TYR A2303
TRP A2398
 None
 1.04A 2a3bB-5y2aA:
43.3		 2a3bB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 10 PHE A2094
GLY A2137
ASP A2251
TYR A2303
TRP A2398
 None
 0.74A 2a3bB-5y2aA:
43.3		 2a3bB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 10 PHE A2094
GLY A2137
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.39A 2a3bB-5y2aA:
43.3		 2a3bB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TRP A2398
 None
 1.31A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TYR A2250
 None
 1.20A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
ASP A2178
TYR A2250
TYR A2303
 None
 1.03A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
ASP A2178
TYR A2303
TRP A2398
 None
 1.16A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
ASP A2251
TYR A2303
TRP A2398
 None
 0.85A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
GLU A2180
MET A2248
TYR A2250
 None
 0.98A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 12 TYR A2063
TRP A2067
PHE A2094
GLY A2137
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.65A 2a3cA-5y2aA:
12.0		 2a3cA-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TRP A2067
PHE A2094
GLY A2137
ASP A2178
GLU A2180
MET A2248
TYR A2250
 None
 1.07A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 12 TRP A2067
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TRP A2398
 None
 1.24A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TRP A2067
PHE A2094
GLY A2137
ASP A2178
MET A2248
TYR A2250
TYR A2303
 None
 0.89A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 12 TRP A2067
PHE A2094
GLY A2137
ASP A2178
TYR A2303
TRP A2398
 None
 1.07A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 12 TRP A2067
PHE A2094
GLY A2137
ASP A2251
TYR A2303
TRP A2398
 None
 0.73A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 12 TRP A2067
PHE A2094
GLY A2137
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.47A 2a3cB-5y2aA:
43.4		 2a3cB-5y2aA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_B_SCKB951_1
(ACETYLCHOLINESTERASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 8 TYR A2092
ASP A2112
TYR A2064
TYR A2070
 None
 1.49A 2ha2B-5y2aA:
2.5		 2ha2B-5y2aA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TRP A2398
 None
 0.57A 2uy4A-5y2aA:
19.5		 2uy4A-5y2aA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 9 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TYR A2250
 None
 0.52A 2uy4A-5y2aA:
19.5		 2uy4A-5y2aA:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 ALA A2221
PHE A2094
ALA A2093
THR A2065
GLN A2305
 None
 1.27A 2ve3B-5y2aA:
undetectable		 2ve3B-5y2aA:
11.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TRP A2398
 None
 0.68A 2xtkA-5y2aA:
20.7		 2xtkA-5y2aA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 11 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TYR A2250
 None
 0.79A 2xtkA-5y2aA:
20.7		 2xtkA-5y2aA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TRP A2398
 None
 0.58A 2xtkB-5y2aA:
20.7		 2xtkB-5y2aA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		6 / 10 TYR A2063
PHE A2094
GLY A2137
ASP A2178
GLU A2180
TYR A2250
 None
 0.66A 2xtkB-5y2aA:
20.7		 2xtkB-5y2aA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 PHE A2094
GLY A2137
TRP A2138
GLU A2180
ASP A2251
TYR A2303
TRP A2398
 None
 0.83A 3g6mA-5y2aA:
43.4		 3g6mA-5y2aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 11 PHE A2094
GLY A2137
TRP A2138
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.66A 3g6mA-5y2aA:
43.4		 3g6mA-5y2aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A2063
PHE A2094
GLY A2137
GLU A2180
ASP A2251
TYR A2303
TRP A2398
 None
 0.87A 3g6mA-5y2aA:
43.4		 3g6mA-5y2aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A2063
PHE A2094
GLY A2137
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
 None
 0.65A 3g6mA-5y2aA:
43.4		 3g6mA-5y2aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A2138
TYR A2181
MET A2248
ASP A2251
TRP A2256
 None
 0.80A 3g6mA-5y2aA:
43.4		 3g6mA-5y2aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_H_BCZH1001_0
(NEURAMINIDASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A2337
ARG A2332
GLU A2341
GLU A2330
TYR A2340
 None
 1.45A 3k39H-5y2aA:
undetectable		 3k39H-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 6 ILE A2082
TYR A2077
ASP A2404
THR A2331
 None
 1.02A 3q70A-5y2aA:
undetectable		 3q70A-5y2aA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A2094
GLY A2137
TRP A2138
ASP A2178
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
TRP A2398
 None
 0.54A 3wqvA-5y2aA:
55.3		 3wqvA-5y2aA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		10 / 11 PHE A2094
GLY A2137
TRP A2138
ASP A2178
GLU A2180
MET A2248
TYR A2250
ASP A2251
TYR A2303
TRP A2398
 None
 0.56A 3wqwA-5y2aA:
55.4		 3wqwA-5y2aA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 TRP A2067
GLY A2137
TRP A2138
PHE A2336
 None
 0.71A 3wqwA-5y2aA:
55.4		 3wqwA-5y2aA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 6 GLY A2304
ARG A2355
ILE A2342
LEU A2402
 None
 0.91A 4ac9C-5y2aA:
undetectable		 4ac9C-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 6 GLY A2304
ARG A2355
ILE A2342
LEU A2402
 None
 0.92A 4acaC-5y2aA:
undetectable		 4acaC-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ARG A2148
TRP A2185
GLY A2143
 None
 1.01A 4e7cA-5y2aA:
undetectable		 4e7cA-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A2166
LEU A2175
GLY A2174
PHE A2172
ALA A2220
 None
 1.27A 4eb4A-5y2aA:
undetectable		 4eb4A-5y2aA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A2166
LEU A2175
GLY A2174
PHE A2172
ALA A2220
 None
 1.28A 4eb4B-5y2aA:
undetectable		 4eb4B-5y2aA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		3 / 3 PHE A2117
TYR A2077
TYR A2064
 None
 1.02A 4ffwA-5y2aA:
undetectable		 4ffwA-5y2aA:
7.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 HIS A2262
GLN A2305
GLY A2304
SER A2373
 None
 1.31A 4fu8A-5y2aA:
undetectable		 4fu8A-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA302_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 TYR A2303
GLN A2305
GLY A2304
SER A2373
 None
 1.18A 4fu8A-5y2aA:
undetectable		 4fu8A-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG1_A_ACTA504_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 SER A2225
LYS A2226
ARG A2227
ASP A2274
 None
 1.50A 4ig1A-5y2aA:
undetectable		 4ig1A-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NSB_A_AINA402_1
(CHITINASE-3-LIKE
PROTEIN 1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 7 THR A2065
TRP A2067
ARG A2071
TRP A2398
LEU A2402
 None
 0.72A 4nsbA-5y2aA:
51.2		 4nsbA-5y2aA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 PHE A2374
TYR A2250
ALA A2264
ALA A2380
ALA A2397
 None
 1.06A 4oaeA-5y2aA:
undetectable		 4oaeA-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A2299
ILE A2245
SER A2246
MET A2396
ALA A2224
 None
 1.11A 4qtuB-5y2aA:
undetectable		 4qtuB-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA406_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 SER A2225
LYS A2226
ARG A2227
ASP A2274
 None
 1.21A 4xdtA-5y2aA:
undetectable		 4xdtA-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A2138
GLU A2180
ASP A2251
 None
 0.22A 5gqbA-5y2aA:
43.1		 5gqbA-5y2aA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		7 / 8 PHE A2094
GLY A2137
TRP A2138
GLU A2180
TYR A2250
ASP A2251
TRP A2398
 None
 0.55A 5gqbA-5y2aA:
43.1		 5gqbA-5y2aA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 6 PHE A2378
ARG A2355
ASP A2356
GLY A2358
 None
 1.26A 5mraA-5y2aA:
undetectable
5mraB-5y2aA:
undetectable		 5mraA-5y2aA:
16.67
5mraB-5y2aA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		5 / 12 LEU A2177
LEU A2135
GLY A2136
GLY A2137
LEU A2149
 None
 1.16A 5uc1A-5y2aA:
undetectable		 5uc1A-5y2aA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 ARG A2332
GLY A2075
ASN A2074
ASP A2073
 None
 1.36A 6dwjB-5y2aA:
undetectable
6dwjD-5y2aA:
undetectable		 6dwjB-5y2aA:
undetectable
6dwjD-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HXI_B_ACTB706_0
(SUCCINYL-COA LIGASE
(ADP-FORMING)
SUBUNIT ALPHA)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 5 HIS A2437
VAL A2346
ARG A2355
PHE A2374
 None
 1.18A 6hxiB-5y2aA:
undetectable		 6hxiB-5y2aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 5y2a INSECT GROUP II
CHITINASE
(Ostrinia
furnacalis) 		4 / 7 ILE A2090
GLU A2085
HIS A2127
VAL A2129
 None
 1.16A 6j20A-5y2aA:
undetectable		 6j20A-5y2aA:
undetectable