SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		3 / 3 PHE A 299
TRP A 293
GLU A 291
 None
 1.11A 1mogA-5y31A:
undetectable		 1mogA-5y31A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NCW_H_BEZH601_0
(IMMUNOGLOBULIN IGG2A)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.34A 1ncwH-5y31A:
undetectable
1ncwL-5y31A:
undetectable		 1ncwH-5y31A:
undetectable
1ncwL-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 7 PHE A 414
ALA A 375
TYR A 422
ILE A 241
 None
 1.08A 1oniA-5y31A:
undetectable
1oniB-5y31A:
undetectable		 1oniA-5y31A:
undetectable
1oniB-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 7 TYR A 422
ILE A 241
PHE A 414
ALA A 375
 None
 1.10A 1oniG-5y31A:
undetectable
1oniI-5y31A:
undetectable		 1oniG-5y31A:
undetectable
1oniI-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 7 THR B 134
PHE B 135
SER B  83
LEU B 151
 None
 1.03A 1qcaA-5y31B:
undetectable		 1qcaA-5y31B:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.41A 1ru9H-5y31A:
undetectable
1ru9L-5y31A:
undetectable		 1ru9H-5y31A:
undetectable
1ru9L-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 10 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.38A 1ruaH-5y31A:
undetectable
1ruaL-5y31A:
undetectable		 1ruaH-5y31A:
undetectable
1ruaL-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.37A 1rulH-5y31A:
undetectable
1rulL-5y31A:
undetectable		 1rulH-5y31A:
undetectable
1rulL-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUM_H_BEZH1601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.33A 1rumH-5y31A:
undetectable
1rumL-5y31A:
undetectable		 1rumH-5y31A:
undetectable
1rumL-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 574
LEU A 604
GLY A 637
GLY A 649
TYR A 650
 None
 1.33A 1rupH-5y31A:
undetectable
1rupL-5y31A:
undetectable		 1rupH-5y31A:
undetectable
1rupL-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 7 MET A 366
ALA A 266
PHE A 360
ARG A 256
 None
 1.26A 1t9wA-5y31A:
undetectable		 1t9wA-5y31A:
5.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 5 VAL A 693
GLY A 692
VAL A 701
TRP A 706
 None
 1.07A 1tkqB-5y31A:
undetectable		 1tkqB-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP B 240
GLU B 383
TYR B 433
 None
 0.84A 1wsvA-5y31B:
undetectable		 1wsvA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 7 PHE A 360
ASN A 247
HIS A 255
VAL A 269
 None
 1.00A 1wu8A-5y31A:
3.5
1wu8C-5y31A:
3.4		 1wu8A-5y31A:
13.39
1wu8C-5y31A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 12 LEU A 434
LEU A 426
GLY A 346
SER A 428
ALA A 343
 None
 1.18A 2bm9D-5y31A:
undetectable		 2bm9D-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		5 / 9 LEU B  96
ILE B  82
PHE B 135
THR B 134
LEU B 120
 None
 1.10A 2m9qA-5y31B:
undetectable		 2m9qA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		5 / 9 LEU B  96
ILE B 122
PHE B 135
THR B 134
LEU B 120
 None
 1.15A 2m9qA-5y31B:
undetectable		 2m9qA-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE B  61
PHE B  98
ILE B 122
PHE B 111
 None
 0.95A 2q6hA-5y31B:
undetectable		 2q6hA-5y31B:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 7 ILE B  61
PHE B  98
ILE B 122
PHE B 111
 None
 0.95A 2qb4A-5y31B:
undetectable		 2qb4A-5y31B:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 7 THR B 545
GLN B 230
ILE B 547
SER B 236
 None
 1.14A 2xytI-5y31B:
undetectable		 2xytI-5y31B:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 8 ILE A 707
ASN A 712
SER A 689
SER A 709
 None
 0.92A 2zw9B-5y31A:
undetectable		 2zw9B-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		5 / 11 PHE B  87
SER B  86
ILE B 106
PHE B 111
PHE B  98
 None
 1.39A 3a9eB-5y31B:
undetectable		 3a9eB-5y31B:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 10 PHE A 330
VAL A 270
ILE A 285
TYR A 277
ILE A 378
 None
 1.22A 3ihzA-5y31A:
undetectable		 3ihzA-5y31A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE B 278
GLY B 280
PHE B 318
ALA B 300
VAL B 299
 None
 0.96A 3jb2A-5y31B:
undetectable		 3jb2A-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		3 / 3 LEU B 385
TRP B 460
GLY B 461
 None
 0.78A 3l35A-5y31B:
undetectable
3l35H-5y31B:
undetectable		 3l35A-5y31B:
undetectable
3l35H-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 12 GLY A 341
ILE A 241
GLY A 355
ALA A 343
ALA A 375
 None
 0.92A 3sudB-5y31A:
undetectable		 3sudB-5y31A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 12 GLY A 341
ILE A 241
GLY A 356
ALA A 343
ALA A 375
 None
 1.10A 3sudB-5y31A:
undetectable		 3sudB-5y31A:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 11 PHE A 330
VAL A 270
ILE A 285
TYR A 277
ILE A 378
 None
 1.23A 3vawA-5y31A:
undetectable		 3vawA-5y31A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZTV_A_ADNA1600_1
(NAD NUCLEOTIDASE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 377
GLY A 347
GLY A 346
PHE A 425
GLY A 354
 None
 1.26A 3ztvA-5y31A:
undetectable		 3ztvA-5y31A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 7 ASN B 531
GLU B 248
ILE B 530
ASN B 534
 None
 1.11A 4d39B-5y31B:
undetectable		 4d39B-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 5 PHE B  98
PHE B 111
ILE B  82
THR B 134
 None
 0.75A 4ejjC-5y31B:
undetectable		 4ejjC-5y31B:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 6 GLY A 430
GLY A 431
ASN A 526
ILE A 378
 None
None
CA  A 803 (-3.2A)
None
 0.99A 4fglD-5y31A:
undetectable		 4fglD-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 377
GLY A 347
GLY A 346
PHE A 425
GLY A 354
 None
 1.34A 4h2fA-5y31A:
undetectable		 4h2fA-5y31A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 9 ASN A 377
GLY A 347
GLY A 346
PHE A 425
GLY A 354
 None
 1.32A 4h2gA-5y31A:
undetectable		 4h2gA-5y31A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		3 / 3 LEU A 604
ARG A 550
MET A 661
 None
 0.86A 4m11C-5y31A:
undetectable		 4m11C-5y31A:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTS_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 12 GLY A 448
ASP A 459
ILE A 452
SER A 439
PRO A 445
 None
CA  A 802 (-3.3A)
None
None
None
 1.14A 4rtsA-5y31A:
undetectable		 4rtsA-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		4 / 5 TYR A 344
PHE A 335
HIS A 328
LEU A 329
 None
 1.27A 5csyB-5y31A:
undetectable		 5csyB-5y31A:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_B_K1SB304_0
(ADP-SUGAR
PYROPHOSPHATASE)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 5 TRP B 187
VAL B 185
LEU B 170
TRP B 183
 None
 1.49A 5qjqA-5y31B:
undetectable
5qjqB-5y31B:
2.4		 5qjqA-5y31B:
undetectable
5qjqB-5y31B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE B 272
SER B 229
ILE B 547
ARG B 533
GLU B 269
 None
 1.12A 5vceA-5y31B:
undetectable		 5vceA-5y31B:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 5y31 DISINTEGRIN AND
METALLOPROTEINASE
DOMAIN-CONTAINING
PROTEIN 22
(Homo
sapiens) 		5 / 12 ILE A 345
LEU A 642
GLY A 341
ALA A 342
LEU A 306
 None
 1.22A 5zwrA-5y31A:
undetectable		 5zwrA-5y31A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5y31 LEUCINE-RICH
GLIOMA-INACTIVATED
PROTEIN 1
(Homo
sapiens) 		4 / 6 ALA B 110
LEU B 146
SER B 131
ASN B 125
 None
 0.94A 6f88B-5y31B:
undetectable		 6f88B-5y31B:
22.50