SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_A_ACHA1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5y39	RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR5 (Homo sapiens; Homo sapiens)	4 / 7	CYH E 148 GLN A 130 ILE A 124 SER A 133	None	1.30A	2xz5A-5y39E: undetectable 2xz5B-5y39E: undetectable	2xz5A-5y39E: undetectable 2xz5B-5y39E: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_E_ACHE1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5y39	RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR5 (Homo sapiens; Homo sapiens)	4 / 7	GLN A 130 ILE A 124 SER A 133 CYH E 148	None	1.31A	2xz5D-5y39A: undetectable 2xz5E-5y39A: undetectable	2xz5D-5y39A: undetectable 2xz5E-5y39A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HU9_S_PCFS603_0 (CYTOCHROME B-C1 COMPLEX SUBUNIT 8 CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL)	5y39	RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR5 (Homo sapiens; Homo sapiens)	4 / 7	GLY E 163 HIS E 161 VAL E 166 SER A 144	None	0.97A	6hu9S-5y39E: undetectable 6hu9q-5y39E: undetectable	6hu9S-5y39E: undetectable 6hu9q-5y39E: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XZ5_A_ACHA1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","5y39","RAGULATOR COMPLEX PROTEIN LAMTOR1;RAGULATOR COMPLEX PROTEIN LAMTOR5","Homo sapiens;Homo sapiens",4,"CYH E 148;GLN A 130;ILE A 124;SER A 133","None","1.30A","2xz5A-5y39E:undetectable;2xz5B-5y39E:undetectable","2xz5A-5y39E:undetectable;2xz5B-5y39E:undetectable"],["2XZ5_E_ACHE1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","5y39","RAGULATOR COMPLEX PROTEIN LAMTOR1;RAGULATOR COMPLEX PROTEIN LAMTOR5","Homo sapiens;Homo sapiens",4,"GLN A 130;ILE A 124;SER A 133;CYH E 148","None","1.31A","2xz5D-5y39A:undetectable;2xz5E-5y39A:undetectable","2xz5D-5y39A:undetectable;2xz5E-5y39A:undetectable"],["6HU9_S_PCFS603_0","CYTOCHROME B-C1 COMPLEX SUBUNIT 8;CYTOCHROME C OXIDASE POLYPEPTIDE 5A, MITOCHONDRIAL","5y39","RAGULATOR COMPLEX PROTEIN LAMTOR1;RAGULATOR COMPLEX PROTEIN LAMTOR5","Homo sapiens;Homo sapiens",4,"GLY E 163;HIS E 161;VAL E 166;SER A 144","None","0.97A","6hu9S-5y39E:undetectable;6hu9q-5y39E:undetectable","6hu9S-5y39E:undetectable;6hu9q-5y39E:undetectable"]]