SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 11 LEU A 580
HIS A 584
ALA A 583
PHE A 605
GLY A 607
 None
 1.31A 1cmaA-5y3jA:
undetectable
1cmaB-5y3jA:
undetectable		 1cmaA-5y3jA:
undetectable
1cmaB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
LEU A 196
VAL A 190
 None
 1.03A 1hrkA-5y3jA:
undetectable		 1hrkA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 SER A 162
LEU A 172
MET A 174
ILE A 155
LEU A 158
 None
 1.23A 1lhuA-5y3jA:
undetectable		 1lhuA-5y3jA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 8 TYR A 229
VAL A 290
HIS A 231
ASP A 250
 None
 1.22A 1s3zA-5y3jA:
undetectable
1s3zB-5y3jA:
undetectable		 1s3zA-5y3jA:
undetectable
1s3zB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 11 LEU A 703
ASN A 735
ILE A 713
LEU A 692
PHE A 721
 None
 1.35A 1tw4A-5y3jA:
undetectable		 1tw4A-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 11 LEU A 703
ASN A 735
LEU A 692
VAL A 740
PHE A 721
 None
 1.16A 1tw4A-5y3jA:
undetectable		 1tw4A-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 5 LEU A 384
LEU A 393
LEU A 363
LEU A 396
 None
 1.05A 1yajD-5y3jA:
undetectable		 1yajD-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 LYS A 207
ASP A 314
ASP A 370
 None
 0.93A 2br4A-5y3jA:
undetectable		 2br4A-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 11 LEU A 211
LEU A 206
SER A 162
LEU A 158
LEU A 188
 None
 0.90A 2ceoA-5y3jA:
undetectable		 2ceoA-5y3jA:
12.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA701_0
(FERROCHELATASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
LEU A 196
VAL A 190
 None
 1.04A 2hrcA-5y3jA:
undetectable		 2hrcA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
LEU A 196
VAL A 190
 None
 1.09A 2hrcB-5y3jA:
undetectable		 2hrcB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 5 PHE A 721
PHE A 745
PHE A 773
VAL A 716
 None
 1.11A 2lh6A-5y3jA:
undetectable		 2lh6A-5y3jA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
LEU A 196
VAL A 190
 None
 0.96A 2po5A-5y3jA:
undetectable		 2po5A-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
LEU A 196
VAL A 190
 None
 0.95A 2po7A-5y3jA:
undetectable		 2po7A-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 ARG A 497
LEU A 479
LEU A 501
ILE A 420
ARG A 546
 None
 1.18A 2v0mC-5y3jA:
undetectable		 2v0mC-5y3jA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 679
LEU A 675
GLY A 649
TRP A 614
LEU A 684
 None
 1.21A 2w8yA-5y3jA:
undetectable		 2w8yA-5y3jA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 6 SER A 758
ARG A 787
PRO A 785
GLY A 783
 None
 1.37A 2y7pA-5y3jA:
undetectable		 2y7pA-5y3jA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 356
THR A 355
MET A 371
ILE A 410
SER A 380
 None
 1.47A 2ydoA-5y3jA:
undetectable		 2ydoA-5y3jA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 356
THR A 355
MET A 371
LEU A 379
ILE A 410
 None
 1.17A 2ydoA-5y3jA:
undetectable		 2ydoA-5y3jA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_D_VD3D2001_1
(VITAMIN D
HYDROXYLASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 ILE A 410
LEU A 379
LEU A 369
ALA A 388
LEU A 417
 None
 1.09A 3a50D-5y3jA:
undetectable		 3a50D-5y3jA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 THR A 118
LEU A 128
LEU A  94
LEU A  92
 None
 0.84A 3bgdB-5y3jA:
undetectable		 3bgdB-5y3jA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 THR A 647
LEU A 635
LEU A 640
LEU A 610
 None
 0.92A 3bgdB-5y3jA:
undetectable		 3bgdB-5y3jA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 398
LEU A 477
PHE A 376
ILE A 403
ALA A 406
 None
 1.12A 3n8xB-5y3jA:
undetectable		 3n8xB-5y3jA:
9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 LEU A 333
ALA A 329
SER A 359
THR A 327
 None
 0.92A 3ozkB-5y3jA:
undetectable		 3ozkB-5y3jA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 ASP A 314
GLU A 368
SER A 228
 None
 0.62A 3p2kA-5y3jA:
undetectable		 3p2kA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 ASP A 683
GLU A 729
SER A 606
 None
 0.75A 3p2kA-5y3jA:
undetectable		 3p2kA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 LEU A 600
ARG A 659
ASN A 608
 None
 0.69A 3qxvD-5y3jA:
undetectable		 3qxvD-5y3jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 ILE A 403
PHE A 376
LEU A 369
MET A 371
LEU A 384
 None
 1.21A 3s79A-5y3jA:
undetectable		 3s79A-5y3jA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 535
LEU A 595
PHE A 541
LEU A 550
ALA A 602
 None
 1.17A 3vw7A-5y3jA:
undetectable		 3vw7A-5y3jA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 225
LEU A 222
ILE A 232
SER A 221
VAL A 190
 None
 1.33A 3w1wA-5y3jA:
undetectable		 3w1wA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 ASN A 318
THR A 327
LEU A 313
PHE A 304
 None
 0.84A 4ejjD-5y3jA:
undetectable		 4ejjD-5y3jA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 8 TYR A 173
LEU A 226
LEU A 201
LEU A 222
 None
 0.84A 4l1xA-5y3jA:
undetectable		 4l1xA-5y3jA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 LEU A 660
ARG A 659
MET A 467
 None
 0.81A 4m11C-5y3jA:
undetectable		 4m11C-5y3jA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 ARG A 738
ILE A 801
PHE A 770
LEU A 806
 None
 1.06A 4mmcA-5y3jA:
undetectable		 4mmcA-5y3jA:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 5 ASN A 531
LEU A 533
SER A 553
LEU A 550
 None
 1.18A 4n09C-5y3jA:
undetectable		 4n09C-5y3jA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 5 TYR A 554
HIS A 530
ASP A 604
ASP A 465
 None
 1.34A 4qdjA-5y3jA:
undetectable		 4qdjA-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 PHE A 517
ILE A 508
LEU A 484
LEU A 498
LEU A 501
 None
 1.13A 4qynB-5y3jA:
undetectable		 4qynB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 PHE A 720
ILE A 713
LEU A 689
LEU A 703
LEU A 706
 None
 1.19A 4qynB-5y3jA:
undetectable		 4qynB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		3 / 3 ASN A 662
SER A 636
SER A 606
 None
 0.78A 5gsnA-5y3jA:
undetectable		 5gsnA-5y3jA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 333
LEU A 296
PHE A 304
PHE A 280
LEU A 235
 None
 1.22A 5iepA-5y3jA:
undetectable		 5iepA-5y3jA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 SER A 131
ASN A 129
ASP A 175
TYR A 132
SER A  72
 None
 1.07A 5iqbA-5y3jA:
undetectable		 5iqbA-5y3jA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_D_KAND600_1
(BIFUNCTIONAL AAC/APH)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 SER A 131
ASN A 129
ASP A 175
TYR A 132
SER A  72
 None
 1.06A 5iqbD-5y3jA:
undetectable		 5iqbD-5y3jA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_C_NMYC600_1
(BIFUNCTIONAL AAC/APH)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 SER A 131
ASN A 129
ASP A 175
TYR A 132
SER A  72
 None
 1.03A 5iqeC-5y3jA:
undetectable		 5iqeC-5y3jA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQE_D_NMYD600_1
(BIFUNCTIONAL AAC/APH)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 SER A 131
ASN A 129
ASP A 175
TYR A 132
SER A  72
 None
 1.05A 5iqeD-5y3jA:
undetectable		 5iqeD-5y3jA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 7 LEU A 682
GLU A 729
ASN A 711
ILE A 713
 None
 0.99A 5jh7C-5y3jA:
undetectable		 5jh7C-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 ILE A 403
PHE A 376
LEU A 369
MET A 371
LEU A 384
 None
 1.19A 5jkvA-5y3jA:
undetectable		 5jkvA-5y3jA:
10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 4 ASN A 318
LEU A 320
SER A 342
LEU A 339
 None
 1.26A 5kb5A-5y3jA:
undetectable		 5kb5A-5y3jA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 4 ASN A 531
LEU A 533
SER A 553
LEU A 550
 None
 1.14A 5kb5A-5y3jA:
undetectable		 5kb5A-5y3jA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 8 LEU A 356
MET A 371
LEU A 379
ILE A 410
 None
 0.89A 5mzjA-5y3jA:
undetectable		 5mzjA-5y3jA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 6 ILE A 427
LEU A 379
PHE A 376
PHE A 492
 None
 0.96A 5vkqA-5y3jA:
undetectable
5vkqB-5y3jA:
undetectable		 5vkqA-5y3jA:
undetectable
5vkqB-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 6 PHE A 492
ILE A 427
LEU A 379
PHE A 376
 None
 0.96A 5vkqA-5y3jA:
undetectable
5vkqD-5y3jA:
undetectable		 5vkqA-5y3jA:
undetectable
5vkqD-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		4 / 4 PHE A  83
LEU A  42
LEU A  70
VAL A  65
 None
 1.26A 5xxiA-5y3jA:
undetectable		 5xxiA-5y3jA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 LEU A 640
SER A 589
HIS A 588
VAL A 591
ALA A 615
 None
MG  A1011 (-2.7A)
None
None
None
 1.09A 6djzC-5y3jA:
undetectable		 6djzC-5y3jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5y3j TOLL-LIKE RECEPTOR 9
(Equus
caballus) 		5 / 12 VAL A 190
LEU A 195
GLU A 189
LEU A 204
LEU A 218
 None
 0.96A 6f6iA-5y3jA:
undetectable
6f6iB-5y3jA:
undetectable		 6f6iA-5y3jA:
17.24
6f6iB-5y3jA:
22.09