SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y4j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PJ7_A_FFOA2887_1
(N,N-DIMETHYLGLYCINE
OXIDASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		3 / 3 ASP A  57
THR A  90
GLU A 181
 None
XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
 0.79A 1pj7A-5y4jA:
undetectable		 1pj7A-5y4jA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 4 VAL A 272
ALA A 268
LEU A 383
PHE A 269
 None
 1.13A 1q97B-5y4jA:
undetectable		 1q97B-5y4jA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 GLY A  14
GLU A 217
HIS A 285
PHE A  13
VAL A  51
 None
MG  A 401 ( 2.8A)
None
None
None
 1.34A 1qu3A-5y4jA:
undetectable		 1qu3A-5y4jA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 10 GLY A 282
HIS A 243
THR A  12
HIS A 285
THR A 133
 None
 1.28A 1utdQ-5y4jA:
undetectable
1utdR-5y4jA:
undetectable		 1utdQ-5y4jA:
16.30
1utdR-5y4jA:
16.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		10 / 10 TRP A  16
HIS A  54
PHE A  94
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
ASP A 287
LYS A 289
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.9A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
None
 0.24A 1xidA-5y4jA:
60.5		 1xidA-5y4jA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 10 TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.28A 1xidA-5y4jA:
60.5		 1xidA-5y4jA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.33A 1xihA-5y4jA:
60.5		 1xihA-5y4jA:
99.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIH_A_SORA389_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
THR A  90
PHE A  94
VAL A 135
TRP A 137
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 ( 4.9A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.17A 1xihA-5y4jA:
60.5		 1xihA-5y4jA:
99.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 GLY A 225
ALA A 224
GLY A 219
VAL A 218
PRO A 182
 None
 1.11A 2avsB-5y4jA:
undetectable		 2avsB-5y4jA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 ALA A 262
GLY A 263
ASN A 250
ALA A 267
GLN A 222
GLY A 251
 None
 1.47A 2pkmA-5y4jA:
undetectable		 2pkmA-5y4jA:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 ILE A 244
HIS A 243
LEU A 241
GLY A 282
 None
 0.70A 2vdbA-5y4jA:
undetectable		 2vdbA-5y4jA:
21.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.24A 2xinA-5y4jA:
57.1		 2xinA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
None
 1.37A 2xinA-5y4jA:
57.1		 2xinA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.51A 2xinA-5y4jA:
57.1		 2xinA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
None
 1.37A 2xinB-5y4jA:
57.0		 2xinB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.22A 2xinB-5y4jA:
57.0		 2xinB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.49A 2xinB-5y4jA:
57.0		 2xinB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
None
 1.39A 2xinC-5y4jA:
57.1		 2xinC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.21A 2xinC-5y4jA:
57.1		 2xinC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.53A 2xinC-5y4jA:
57.1		 2xinC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
None
 1.36A 2xinD-5y4jA:
52.2		 2xinD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.50A 2xinD-5y4jA:
52.2		 2xinD-5y4jA:
66.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 5 ILE A 176
THR A 119
PHE A 104
PHE A 162
 None
 1.39A 3em0A-5y4jA:
undetectable		 3em0A-5y4jA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 HIS A  54
ASN A 215
GLY A  14
HIS A 285
MET A  88
 XYL  A 402 (-3.8A)
None
None
None
None
 1.40A 3g1uA-5y4jA:
undetectable		 3g1uA-5y4jA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		3 / 3 GLU A 217
GLU A 181
TRP A  16
 MG  A 401 ( 2.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.1A)
 1.30A 3hrdA-5y4jA:
undetectable
3hrdE-5y4jA:
undetectable
3hrdF-5y4jA:
undetectable		 3hrdA-5y4jA:
23.25
3hrdE-5y4jA:
23.25
3hrdF-5y4jA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 GLY A  62
ARG A  68
PRO A  36
ASP A  56
LEU A  15
 None
 1.10A 3m6vA-5y4jA:
2.2		 3m6vA-5y4jA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 GLY A  62
ARG A  68
PRO A  36
ASP A  56
LEU A  15
 None
 1.10A 3m6vB-5y4jA:
undetectable		 3m6vB-5y4jA:
25.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
MET A  88
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.31A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
TRP A 137
HIS A 220
ASP A 287
ASP A 255
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.33A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.13A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.70A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.21A 3ximA-5y4jA:
57.2		 3ximA-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 HIS A  54
THR A  90
GLU A 217
ASP A 257
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
MG  A 401 ( 2.8A)
None
MG  A 401 ( 3.0A)
 1.50A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.33A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.14A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.26A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
HIS A 220
ASP A 287
ASP A 255
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.28A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.20A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		9 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.62A 3ximB-5y4jA:
57.2		 3ximB-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 None
XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.30A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
GLU A 181
HIS A 220
ASP A 287
ASP A 255
 None
XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.41A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
None
MG  A 401 ( 3.0A)
 1.32A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.26A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 ( 4.1A)
None
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.09A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.22A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		9 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-4.1A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.73A 3ximC-5y4jA:
56.8		 3ximC-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
None
MG  A 401 ( 3.0A)
 1.49A 3ximD-5y4jA:
57.3		 3ximD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.23A 3ximD-5y4jA:
57.3		 3ximD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.10A 3ximD-5y4jA:
57.3		 3ximD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.20A 3ximD-5y4jA:
57.3		 3ximD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
LYS A 183
ASP A 255
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
XYL  A 402 ( 4.9A)
 0.75A 3ximD-5y4jA:
57.3		 3ximD-5y4jA:
66.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
VAL A 135
ASN A 215
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
None
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.20A 4dvoA-5y4jA:
60.5		 4dvoA-5y4jA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 287
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.39A 4dvoA-5y4jA:
60.5		 4dvoA-5y4jA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
TRP A 137
HIS A 220
ASP A 287
ASP A 255
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.45A 4dvoA-5y4jA:
60.5		 4dvoA-5y4jA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
ASN A 215
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
None
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 0.22A 4dvoA-5y4jA:
60.5		 4dvoA-5y4jA:
99.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DVO_A_SORA404_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		10 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
ASN A 215
HIS A 220
ASP A 255
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
None
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.68A 4dvoA-5y4jA:
60.5		 4dvoA-5y4jA:
99.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 CYH A 306
GLY A 261
ILE A 312
PHE A  11
ARG A 284
 None
 1.49A 4kosA-5y4jA:
undetectable		 4kosA-5y4jA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 PHE A 162
THR A 119
LEU A  93
ILE A 180
 None
 0.99A 4l4cB-5y4jA:
undetectable		 4l4cB-5y4jA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		3 / 3 ASN A  92
ASP A  57
ASP A 287
 None
None
XYL  A 402 ( 2.9A)
 0.88A 4obwD-5y4jA:
undetectable		 4obwD-5y4jA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 6 ARG A 321
ALA A 379
ASP A 273
SER A 333
 None
 0.96A 4ot2A-5y4jA:
undetectable		 4ot2A-5y4jA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_C_HQEC503_1
(CATALASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 ILE A 120
PHE A 104
LEU A  93
PHE A  99
 None
 0.85A 4qopC-5y4jA:
undetectable		 4qopC-5y4jA:
24.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.30A 4xiaA-5y4jA:
57.1		 4xiaA-5y4jA:
65.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 287
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.41A 4xiaA-5y4jA:
57.1		 4xiaA-5y4jA:
65.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_A_SORA400_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.19A 4xiaA-5y4jA:
57.1		 4xiaA-5y4jA:
65.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
MET A  88
THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.24A 4xiaB-5y4jA:
57.0		 4xiaB-5y4jA:
65.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		12 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.17A 4xiaB-5y4jA:
57.0		 4xiaB-5y4jA:
65.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 LEU A 241
GLY A 231
VAL A 214
PRO A 216
GLY A 248
 None
 1.30A 5f9zA-5y4jA:
undetectable		 5f9zA-5y4jA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 TRP A 137
GLU A 181
ASP A 257
TRP A  16
 XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
None
XYL  A 402 (-4.1A)
 1.07A 5kgpA-5y4jA:
0.9		 5kgpA-5y4jA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 TRP A 137
GLU A 181
ASP A 257
TRP A  16
 XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
None
XYL  A 402 (-4.1A)
 1.09A 5kgpB-5y4jA:
undetectable		 5kgpB-5y4jA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 6 HIS A 243
ASP A 245
HIS A 285
MET A  88
 None
MG  A 401 ( 3.0A)
None
None
 1.38A 5m45A-5y4jA:
0.0		 5m45A-5y4jA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 6 HIS A 243
ASP A 245
HIS A 285
MET A  88
 None
MG  A 401 ( 3.0A)
None
None
 1.37A 5m45D-5y4jA:
undetectable		 5m45D-5y4jA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 6 HIS A 243
ASP A 245
HIS A 285
MET A  88
 None
MG  A 401 ( 3.0A)
None
None
 1.37A 5m45G-5y4jA:
undetectable		 5m45G-5y4jA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 6 HIS A 243
ASP A 245
HIS A 285
MET A  88
 None
MG  A 401 ( 3.0A)
None
None
 1.37A 5m45J-5y4jA:
0.0		 5m45J-5y4jA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.34A 5nhaA-5y4jA:
40.0		 5nhaA-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_A_SORA503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.28A 5nhaA-5y4jA:
40.0		 5nhaA-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.34A 5nhaB-5y4jA:
40.0		 5nhaB-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_B_SORB503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.28A 5nhaB-5y4jA:
40.0		 5nhaB-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.34A 5nhaC-5y4jA:
39.8		 5nhaC-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_C_SORC503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.28A 5nhaC-5y4jA:
39.8		 5nhaC-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 9 HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.34A 5nhaD-5y4jA:
40.0		 5nhaD-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NHA_D_SORD503_0
(XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 9 TRP A  16
HIS A  54
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.28A 5nhaD-5y4jA:
40.0		 5nhaD-5y4jA:
29.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 PHE A 228
LEU A 226
GLY A 197
VAL A 196
THR A 195
 None
 1.33A 5o4yD-5y4jA:
undetectable
5o4yE-5y4jA:
undetectable		 5o4yD-5y4jA:
2.66
5o4yE-5y4jA:
15.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 HIS A  54
THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 245
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
MG  A 401 ( 3.0A)
None
 1.14A 5ximA-5y4jA:
57.3		 5ximA-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.30A 5ximA-5y4jA:
57.3		 5ximA-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
HIS A 220
ASP A 287
ASP A 255
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.32A 5ximA-5y4jA:
57.3		 5ximA-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.21A 5ximA-5y4jA:
57.3		 5ximA-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		9 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.68A 5ximA-5y4jA:
57.3		 5ximA-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 245
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
 1.31A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 217
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
None
 1.38A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
TRP A 137
GLU A 217
HIS A 220
ASP A 287
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.34A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 MET A  88
THR A  90
TRP A 137
HIS A 220
ASP A 287
ASP A 255
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.42A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.20A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		10 / 12 TRP A  16
HIS A  54
MET A  88
THR A  90
VAL A 135
TRP A 137
LYS A 183
HIS A 220
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.59A 5ximB-5y4jA:
57.3		 5ximB-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		8 / 12 HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 257
 XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
None
 1.28A 5ximC-5y4jA:
57.2		 5ximC-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.27A 5ximC-5y4jA:
57.2		 5ximC-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		6 / 12 THR A  90
TRP A 137
GLU A 181
HIS A 220
ASP A 287
ASP A 255
 XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.33A 5ximC-5y4jA:
57.2		 5ximC-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.17A 5ximC-5y4jA:
57.2		 5ximC-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		10 / 12 TRP A  16
HIS A  54
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
HIS A 220
ASP A 255
ASP A 287
 XYL  A 402 (-4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
XYL  A 402 ( 2.9A)
 0.58A 5ximC-5y4jA:
57.2		 5ximC-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 MET A  88
THR A  90
TRP A 137
GLU A 181
GLU A 217
HIS A 220
ASP A 287
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
 1.28A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		7 / 12 MET A  88
THR A  90
TRP A 137
GLU A 181
HIS A 220
ASP A 287
ASP A 255
 None
XYL  A 402 ( 4.1A)
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 2.9A)
XYL  A 402 ( 4.9A)
 1.37A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 THR A  90
GLU A 181
GLU A 217
ASP A 257
ASP A 245
 XYL  A 402 ( 4.1A)
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
None
MG  A 401 ( 3.0A)
 1.30A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		5 / 12 THR A  90
VAL A 135
GLU A 181
GLU A 217
ASP A 257
 XYL  A 402 ( 4.1A)
None
XYL  A 402 ( 2.4A)
MG  A 401 ( 2.8A)
None
 1.11A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		11 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
GLU A 217
HIS A 220
ASP A 245
ASP A 287
 XYL  A 402 (-4.1A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
MG  A 401 ( 2.8A)
XYL  A 402 (-4.2A)
MG  A 401 ( 3.0A)
XYL  A 402 ( 2.9A)
 0.19A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		9 / 12 TRP A  16
MET A  88
THR A  90
VAL A 135
TRP A 137
GLU A 181
LYS A 183
HIS A 220
ASP A 255
 XYL  A 402 (-4.1A)
None
XYL  A 402 ( 4.1A)
None
XYL  A 402 (-3.8A)
XYL  A 402 ( 2.4A)
XYL  A 402 (-2.8A)
XYL  A 402 (-4.2A)
XYL  A 402 ( 4.9A)
 0.65A 5ximD-5y4jA:
57.3		 5ximD-5y4jA:
66.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		3 / 3 HIS A  54
ASN A  92
LEU A  93
 XYL  A 402 (-3.8A)
None
None
 0.88A 6f7lB-5y4jA:
undetectable		 6f7lB-5y4jA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 TRP A  20
ASP A  57
ASP A 287
GLU A 181
 None
None
XYL  A 402 ( 2.9A)
XYL  A 402 ( 2.4A)
 1.23A 6mn4B-5y4jA:
undetectable		 6mn4B-5y4jA:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5y4j XYLOSE ISOMERASE
(Streptomyces
rubiginosus) 		4 / 8 TRP A  20
ASP A  57
ASP A 287
GLU A 181
 None
None
XYL  A 402 ( 2.9A)
XYL  A 402 ( 2.4A)
 1.03A 6mn4C-5y4jA:
undetectable		 6mn4C-5y4jA:
24.74