SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y4m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W0F_A_STRA1499_1 (CYTOCHROME P450 3A4)	5y4m	- (-)	4 / 4	PHE A 48 ASP A 88 PHE A 89 VAL A 40	None	0.91A	1w0fA-5y4mA: undetectable	1w0fA-5y4mA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_B_ACHB1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	5y4m	- (-)	4 / 8	TYR A 58 SER A 53 GLN A 83 ILE A 172	None	1.09A	2xz5B-5y4mA: undetectable 2xz5E-5y4mA: undetectable	2xz5B-5y4mA: undetectable 2xz5E-5y4mA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A1R_A_STRA600_1 (CYTOCHROME P450 3A4)	5y4m	- (-)	4 / 5	PHE A 48 ASP A 88 PHE A 89 VAL A 40	None	0.82A	5a1rA-5y4mA: undetectable	5a1rA-5y4mA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_A_SUEA1202_0 (NS3 PROTEASE)	5y4m	- (-)	5 / 12	GLY A 56 ARG A 160 ILE A 172 LEU A 174 GLY A 73	None EDO A 203 (-3.1A) None None None	1.00A	6c2mA-5y4mA: undetectable	6c2mA-5y4mA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_A_GLYA715_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	5y4m	- (-)	4 / 6	GLY A 170 ASN A 167 ASP A 108 SER A 106	None	0.98A	6dwdA-5y4mA: undetectable 6dwdC-5y4mA: undetectable	6dwdA-5y4mA: undetectable 6dwdC-5y4mA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1W0F_A_STRA1499_1","CYTOCHROME P450 3A4","5y4m","-","-",4,"PHE A  48;ASP A  88;PHE A  89;VAL A  40","None","0.91A","1w0fA-5y4mA:undetectable","1w0fA-5y4mA:undetectable"],["2XZ5_B_ACHB1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","5y4m","-","-",4,"TYR A  58;SER A  53;GLN A  83;ILE A 172","None","1.09A","2xz5B-5y4mA:undetectable;2xz5E-5y4mA:undetectable","2xz5B-5y4mA:undetectable;2xz5E-5y4mA:undetectable"],["5A1R_A_STRA600_1","CYTOCHROME P450 3A4","5y4m","-","-",4,"PHE A  48;ASP A  88;PHE A  89;VAL A  40","None","0.82A","5a1rA-5y4mA:undetectable","5a1rA-5y4mA:undetectable"],["6C2M_A_SUEA1202_0","NS3 PROTEASE","5y4m","-","-",5,"GLY A  56;ARG A 160;ILE A 172;LEU A 174;GLY A  73","None;EDO A 203 (-3.1A);None;None;None","1.00A","6c2mA-5y4mA:undetectable","6c2mA-5y4mA:undetectable"],["6DWD_A_GLYA715_0","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","5y4m","-","-",4,"GLY A 170;ASN A 167;ASP A 108;SER A 106","None","0.98A","6dwdA-5y4mA:undetectable;6dwdC-5y4mA:undetectable","6dwdA-5y4mA:undetectable;6dwdC-5y4mA:undetectable"]]