SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y4u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5y4u -
(-) 		4 / 7 LEU A 220
GLN A 219
LEU A 186
PHE A 193
 None
 1.03A 1v55C-5y4uA:
undetectable
1v55J-5y4uA:
undetectable		 1v55C-5y4uA:
undetectable
1v55J-5y4uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y4u -
(-) 		4 / 7 LEU A 220
GLN A 219
LEU A 186
PHE A 193
 None
 1.01A 2eijC-5y4uA:
undetectable
2eijJ-5y4uA:
undetectable		 2eijC-5y4uA:
undetectable
2eijJ-5y4uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y4u -
(-) 		4 / 7 LEU A 220
GLN A 219
LEU A 186
PHE A 193
 None
 1.01A 2eimC-5y4uA:
undetectable
2eimJ-5y4uA:
undetectable		 2eimC-5y4uA:
undetectable
2eimJ-5y4uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5y4u -
(-) 		4 / 5 PRO A 171
LEU A 248
TYR A 221
PHE A 226
 None
 1.17A 5igjA-5y4uA:
undetectable		 5igjA-5y4uA:
undetectable