SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y51'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 5y51 -
(-) 		4 / 7 GLY A  47
HIS A  41
TYR A  57
PRO A 178
 None
 1.18A 1th6A-5y51A:
undetectable		 1th6A-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5y51 -
(-) 		4 / 7 GLY A  47
HIS A  41
TYR A  57
PRO A 178
 None
 1.18A 2armA-5y51A:
undetectable		 2armA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5y51 -
(-) 		5 / 12 PHE A 247
TYR A 100
PRO A 251
ALA A  88
ALA A 189
 None
 1.28A 2x2nA-5y51A:
undetectable		 2x2nA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5y51 -
(-) 		5 / 12 PHE A 247
TYR A 100
PRO A 251
ALA A  88
ALA A 189
 None
 1.33A 2x2nC-5y51A:
undetectable		 2x2nC-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 5 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.48A 2yldA-5y51A:
undetectable		 2yldA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 5 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.48A 2ylgA-5y51A:
undetectable		 2ylgA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5y51 -
(-) 		5 / 12 ILE A 192
GLY A  97
VAL A  95
ILE A   6
LEU A 195
 None
 1.00A 3fpjA-5y51A:
undetectable		 3fpjA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 5y51 -
(-) 		4 / 8 ILE A 192
ALA A  96
LEU A  74
ALA A 248
 None
 0.93A 3hrdA-5y51A:
undetectable
3hrdB-5y51A:
undetectable		 3hrdA-5y51A:
undetectable
3hrdB-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 5 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.48A 3zwiA-5y51A:
undetectable		 3zwiA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 4 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.47A 4cipA-5y51A:
undetectable		 4cipA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 5 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.45A 5jliA-5y51A:
undetectable		 5jliA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 4 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.46A 5jslA-5y51A:
undetectable		 5jslA-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5y51 -
(-) 		4 / 5 ALA A  21
GLY A  16
CYH A  18
HIS A 169
 None
 1.47A 5jt4A-5y51A:
undetectable		 5jt4A-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5y51 -
(-) 		3 / 3 THR A  39
PRO A  60
ASP A  63
 None
 0.91A 5l8dB-5y51A:
undetectable		 5l8dB-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5y51 -
(-) 		3 / 3 THR A  39
PRO A  60
ASP A  63
 None
 0.91A 5mwuB-5y51A:
undetectable		 5mwuB-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5y51 -
(-) 		3 / 3 HIS A  34
ARG A  67
ILE A  64
 None
 0.71A 6fgdA-5y51A:
2.7		 6fgdA-5y51A:
undetectable