SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y5s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 5y5s PHOTOSYNTHETIC
REACTION CENTER H
SUBUNIT
(Thermochromatium
tepidum) 		4 / 6 VAL H 239
VAL H 184
ILE H 214
ARG H 180
 None
 1.14A 3mssC-5y5sH:
undetectable		 3mssC-5y5sH:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 5y5s PHOTOSYNTHETIC
REACTION CENTER H
SUBUNIT
(Thermochromatium
tepidum) 		5 / 12 VAL H 184
VAL H 193
MET H 107
GLY H 246
GLY H 198
 None
 1.03A 6brdC-5y5sH:
undetectable		 6brdC-5y5sH:
19.51