SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5y5w SPINDLIN-1
(Homo
sapiens) 		4 / 5 VAL A  54
GLY A  55
VAL A  76
TRP A 165
 None
 1.24A 1tkqB-5y5wA:
undetectable		 1tkqB-5y5wA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 LEU A 190
TRP A 151
TYR A 179
 None
 0.84A 3aicB-5y5wA:
undetectable		 3aicB-5y5wA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 LEU A 190
TRP A 151
TYR A 179
 None
 0.84A 3aicE-5y5wA:
undetectable		 3aicE-5y5wA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 LEU A 190
TRP A 151
TYR A 179
 None
 0.82A 3aicG-5y5wA:
undetectable		 3aicG-5y5wA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 LEU A 190
TRP A 151
TYR A 179
 None
 0.81A 3aicH-5y5wA:
undetectable		 3aicH-5y5wA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 PHE A 251
CYH A  96
HIS A 252
 None
 1.18A 3u9fF-5y5wA:
undetectable		 3u9fF-5y5wA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 PHE A 251
CYH A  96
HIS A 252
 None
 1.19A 3u9fG-5y5wA:
undetectable		 3u9fG-5y5wA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 PHE A 251
CYH A  96
HIS A 252
 None
 1.13A 3u9fS-5y5wA:
undetectable		 3u9fS-5y5wA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5y5w SPINDLIN-1
(Homo
sapiens) 		3 / 3 LYS A 246
ARG A 107
LEU A 100
 None
 0.87A 3v4tE-5y5wA:
undetectable		 3v4tE-5y5wA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_D_ECND403_1
(FLAVOHEMOGLOBIN)		 5y5w SPINDLIN-1
(Homo
sapiens) 		5 / 12 ILE A 123
THR A 131
LEU A 182
TYR A 185
ILE A 192
 None
 1.14A 4g1bD-5y5wA:
undetectable		 4g1bD-5y5wA:
20.73