SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y63'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 5y63 ALKYL HYDROPEROXIDE
REDUCTASE, C SUBUNIT
(Enterococcus
faecalis) 		3 / 3 TYR A  39
TYR A  94
ILE A  92
 None
 0.85A 3eteA-5y63A:
undetectable
3eteB-5y63A:
undetectable		 3eteA-5y63A:
9.54
3eteB-5y63A:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5y63 ALKYL HYDROPEROXIDE
REDUCTASE, C SUBUNIT
(Enterococcus
faecalis) 		4 / 7 HIS A  79
ILE A  92
ILE A  89
ALA A  83
 None
 0.85A 4lv9B-5y63A:
undetectable		 4lv9B-5y63A:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5y63 ALKYL HYDROPEROXIDE
REDUCTASE, C SUBUNIT
(Enterococcus
faecalis) 		4 / 5 GLY A  31
LEU A  30
SER A  34
TYR A  69
 None
 1.17A 6ji6A-5y63A:
undetectable		 6ji6A-5y63A:
undetectable