SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5y6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5y6f FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 6 LEU A 163
GLN A 164
LEU A 139
PHE A 141
 None
 1.07A 2einP-5y6fA:
undetectable
2einW-5y6fA:
undetectable		 2einP-5y6fA:
undetectable
2einW-5y6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 5y6f FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		3 / 3 GLN A  90
LYS A  67
VAL A  65
 None
 0.74A 2jfaB-5y6fA:
undetectable		 2jfaB-5y6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5y6f FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		5 / 11 LEU A 209
LEU A 139
MET A 176
VAL A 174
ILE A 172
 None
 1.20A 2uxoB-5y6fA:
undetectable		 2uxoB-5y6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5y6f FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		5 / 9 ALA A 153
GLY A 150
LEU A 209
ILE A 189
LEU A 188
 None
C2E  A 302 (-2.7A)
None
C2E  A 303 ( 4.1A)
None
 0.95A 2z0yB-5y6fA:
undetectable		 2z0yB-5y6fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5y6f FLAGELLAR BRAKE
PROTEIN YCGR
(Escherichia
coli) 		4 / 8 LEU A  32
ASN A  62
VAL A  65
GLY A  37
 None
 0.75A 3dcjB-5y6fA:
undetectable		 3dcjB-5y6fA:
undetectable